PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa004953

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

ERF

Protein Properties

Length: 214aa MW: 24243.5 Da PI: 5.4469

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-26341	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	47.4	4.8e-15	59	109	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpse.ngkrkrfslgkfgtaeeAakaaiaarkkleg 55 + y+GVr + + +Wv+e +++ n+ + r++lg++ tae+Aa+a++ a+ +++g Lsa004953 59 PVYRGVRMRD-NDKWVCE---VRWpNK-KLRVWLGTHPTAEMAARAHDVAAYAFRG 109 68****99.8**...777554.8*********************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	1.3E-10	59	109	IPR001471	AP2/ERF domain
SMART	SM00380	4.2E-24	60	123	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.55E-19	60	119	IPR016177	DNA-binding domain
PROSITE profile	PS51032	20.455	60	117	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.4E-28	60	119	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.4E-6	61	72	IPR001471	AP2/ERF domain
CDD	cd00018	5.50E-27	61	119	No hit	No description
PRINTS	PR00367	2.4E-6	83	99	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 214 aa Download sequence Send to blast
MDALIEPYSP FIAVVSSKNA LISNCTTVVN TAVEAEVKLA SRNPKKRAGR KKFRETRHPV 60 YRGVRMRDND KWVCEVRWPN KKLRVWLGTH PTAEMAARAH DVAAYAFRGR SACLNFADSV 120 WRLPIPKSNN LQDIQEAAAE AAEAFRETED VVEIVETKEL PETKFKVDEE DVIEMQRYYC 180 GMAEGLMVAP PPTEGYGSYG DSVEFCADDF LWSF

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates abscisic acid- and dehydration-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation. {ECO:0000269\|PubMed:11798174, ECO:0000269\|PubMed:12376631}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By high-salt stress, drought stress and abscisic acid (ABA) treatment. {ECO:0000269\|PubMed:11798174, ECO:0000269\|PubMed:12376631}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023733189.1	1e-159	dehydration-responsive element-binding protein 1D-like
Swissprot	Q9FJ93	6e-61	DRE1D_ARATH; Dehydration-responsive element-binding protein 1D
TrEMBL	A0A2J6KGZ0	1e-158	A0A2J6KGZ0_LACSA; Uncharacterized protein
STRING	Migut.F01149.1.p	4e-72	(Erythranthe guttata)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G25470.1	1e-57	C-repeat/DRE binding factor 2

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guttikonda SK, et al. Overexpression of AtDREB1D transcription factor improves drought tolerance in soybean. Mol. Biol. Rep., 2014. 41(12): p. 7995-8008 [PMID:25192890] Zhang T, et al. Overexpression of a NF-YB3 transcription factor from Picea wilsonii confers tolerance to salinity and drought stress in transformed Arabidopsis thaliana. Plant Physiol. Biochem., 2015. 94: p. 153-64 [PMID:26093308] Carlow CE, et al. Nuclear localization and transactivation by Vitis CBF transcription factors are regulated by combinations of conserved amino acid domains. Plant Physiol. Biochem., 2017. 118: p. 306-319 [PMID:28675818] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470]