PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa004258
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family HSF
Protein Properties Length: 310aa    MW: 35474.1 Da    PI: 5.5419
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58679375PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind107.88.6e-34101012102
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   F+ k+y++++d++l+ +i+w   +nsf+v+++ +f++++Lp yFkh+nf+SFvRQLn+YgF+kv+ ++         weF++++F +g+++ll++i+
     Lsa004258  10 FILKTYQMVNDASLDGFIRWGIANNSFIVVEPLDFSQRLLPAYFKHNNFSSFVRQLNTYGFRKVDPDK---------WEFANEWFLRGQTQLLKNIE 97 
                   9********************888*****************************************999.........******************** PP

                   XXXX CS
  HSF_DNA-bind  99 rkks 102
                   rk++
     Lsa004258  98 RKRQ 101
                   *986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004151.5E-48699IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF467855.58E-31799IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.106.1E-35899IPR011991Winged helix-turn-helix DNA-binding domain
PRINTSPR000562.1E-161033IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004471.5E-281099IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.1E-164860IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043404973IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.1E-166173IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 310 aa     Download sequence    Send to blast
MDSNDIIAPF ILKTYQMVND ASLDGFIRWG IANNSFIVVE PLDFSQRLLP AYFKHNNFSS  60
FVRQLNTYGF RKVDPDKWEF ANEWFLRGQT QLLKNIERKR QIHNRNFMRG EEDEEDEMAM  120
EIARLKQEQK ALEQELVGMN KRLEATERRP EQMMALLHKV AEDPEILPRM MLEKDQRSKR  180
LLKKKRQRNL IPPPPPSSSS RVKFEEEECQ IIEGWTTSSP EAYYGNEPFW QSSSSPNTPS  240
MAWPMSKVGS GGGGAAVNME YAPMNGINRY VNFTDGIGGG YDINYSGGPS PEPDVRPSPA  300
YPFSLLGGGF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B2e-2279926129Heat shock factor protein 1
5d5v_B2e-2279926129Heat shock factor protein 1
5d5v_D2e-2279926129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1182187KKKRQR
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023760271.10.0heat stress transcription factor C-1-like
SwissprotQ9LV522e-79HSFC1_ARATH; Heat stress transcription factor C-1
TrEMBLA0A2J6LLF00.0A0A2J6LLF0_LACSA; Uncharacterized protein
STRINGXP_009588171.11e-103(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G24520.12e-77heat shock transcription factor C1
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Guan Q,Yue X,Zeng H,Zhu J
    The protein phosphatase RCF2 and its interacting partner NAC019 are critical for heat stress-responsive gene regulation and thermotolerance in Arabidopsis.
    Plant Cell, 2014. 26(1): p. 438-53
    [PMID:24415771]