PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa003778

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

bZIP

Protein Properties

Length: 337aa MW: 36585 Da PI: 6.798

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58688436	PU_ref	Unigene	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	75.8	5.7e-24	243	305	1	63
XXXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 1 ekelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 e+elkr++rkq+NRe+ArrsR+RK+ae+eeL+ +v++L++eN++L++el +l++e+ +l+se+ Lsa003778 243 ERELKRQKRKQSNRESARRSRLRKQAECEELQARVEALSNENHSLRDELRRLSEECGNLTSEN 305 89***********************************************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF07777	1.5E-19	1	85	IPR012900	G-box binding protein, multifunctional mosaic region
Gene3D	G3DSA:1.20.5.170	9.9E-21	237	302	No hit	No description
SMART	SM00338	1.1E-23	243	307	IPR004827	Basic-leucine zipper domain
Pfam	PF00170	2.3E-21	243	305	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	13.208	245	308	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	4.31E-12	246	302	No hit	No description
CDD	cd14702	4.53E-25	248	298	No hit	No description
PROSITE pattern	PS00036	0	250	265	IPR004827	Basic-leucine zipper domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 337 aa Download sequence Send to blast
MGAEEQSSPA KHSKPTSTHE TTPPPYPDWS QACYSSGFAP PFFASSPAPP YMWGGQHPMM 60 PPYGTPVPYP TMYPPPGIYS HPSMPRTPGQ TNLELEVKAS NGKDRAPNKK PKGNSGNSNA 120 GGGRAASSSG NDGATQSAES GNDVSSDGTD EDDQQEYSGS KKGSFHQMLA DANARNNNSG 180 SNIQTPVPGN PVASMPPTDL NMGIDLWNPS TGTGSMKLQK NHSGVHQTPA PPPMMSDHWV 240 QDERELKRQK RKQSNRESAR RSRLRKQAEC EELQARVEAL SNENHSLRDE LRRLSEECGN 300 LTSENNSIKD ELTRFLGPEA VSKLDTQLQS QTRKGDS

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	259	265	RRSRLRK
2	259	266	RRSRLRKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Binds to the G-box motif (5'-CCACGTGG-3') of the rbcS-1A gene promoter (PubMed:1373374). G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control. Binds to the G-box motif 5'-CACGTG-3' of LHCB2.4 (At3g27690) promoter. May act as transcriptional activator in light-regulated expression of LHCB2.4. Probably binds DNA as monomer. DNA-binding activity is redox-dependent (PubMed:22718771). {ECO:0000269\|PubMed:1373374, ECO:0000269\|PubMed:22718771}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023753476.1	0.0	G-box-binding factor 1-like isoform X1
Swissprot	P42774	3e-96	GBF1_ARATH; G-box-binding factor 1
TrEMBL	A0A2J6M194	0.0	A0A2J6M194_LACSA; Uncharacterized protein
STRING	EOX91157	1e-129	(Theobroma cacao)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36730.1	1e-64	G-box binding factor 1

Publications ? help Back to Top
Gangappa SN,Srivastava AK,Maurya JP,Ram H,Chattopadhyay S Z-box binding transcription factors (ZBFs): a new class of transcription factors in Arabidopsis seedling development. Mol Plant, 2013. 6(6): p. 1758-68 [PMID:24157607] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Karumuri S,Bandopadhyay R In silico analysis of the structure and interaction of COP1 protein of Arabidopsis thaliana. Indian J. Biochem. Biophys., 2014. 51(5): p. 343-9 [PMID:25630103] Smykowski A,Zimmermann P,Zentgraf U CORRECTION. G-Box Binding Factor1 Reduces CATALASE2 Expression and Regulates the Onset of Leaf Senescence in Arabidopsis. Plant Physiol., 2016. 170(2): p. 1164-7 [PMID:26826725] Smykowski A,Fischer SM,Zentgraf U Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor GBF1. Plants (Basel), 2015. 4(3): p. 691-709 [PMID:27135347] Giri MK, et al. GBF1 differentially regulates CAT2 and PAD4 transcription to promote pathogen defense in Arabidopsis thaliana. Plant J., 2017. 91(5): p. 802-815 [PMID:28622438]