PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa003509

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

bZIP

Protein Properties

Length: 273aa MW: 29706.1 Da PI: 6.234

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-17816	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	32.1	2.4e-10	90	137	4	51
XCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 4 lkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkelee 51 k +r + NReA r++R++Kka+ + Le++v L a N++L k++++ Lsa003509 90 KKGKKRPIGNREAVRKYREKKKARAASLEDEVVRLRALNQQLMKRIQS 137 577899999***********************************9985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.20.5.170	1.6E-14	84	155	No hit	No description
SMART	SM00338	6.2E-12	87	154	IPR004827	Basic-leucine zipper domain
Pfam	PF07716	5.2E-14	89	137	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	9.059	89	136	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	8.73E-8	92	138	No hit	No description
CDD	cd14686	6.68E-13	93	146	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 273 aa Download sequence Send to blast
MEDGELDFST QEMFPPPNIG DIPSNDSMDS FFDDIFKDTH ACTHTHTCNP PGPDSSHTHT 60 CYHVHTKIVP AISGDDDKTP TDDTAESAEK KGKKRPIGNR EAVRKYREKK KARAASLEDE 120 VVRLRALNQQ LMKRIQSQAG LEGEVARLKC LLVDIRGRIE GEIGSFPYQK QNLVGNNVGS 180 VNLGGGYVMN PCNMQCGDQV YCLHPDGKSA EDASIHDPGV NGCEFENLQC LGNQNSLLNG 240 LPGCGNEDGF PVANPNPPGG RTKRKGSRTA VSK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the response to zinc ion deficiency. Binds to the consensus sequence 5'-[AG]TGTCGACA[CT]-3' also called zinc deficiency response element (ZDRE). The ZDRE sequence is conserved in the plant kingdom and present in the promoters of genes that constitute the primary response to zinc deficiency, comprising additional ZIP metal transporter genes (PubMed:20479230, PubMed:26306426). Required for zinc accumulation in roots. Mediates the expression of the zinc transporters ZIP3, ZIP4, ZIP5 and ZIP9 during growth in zinc-deficient conditions. ZIP9 transporter is involved in zinc uptake in roots (PubMed:26306426). {ECO:0000269\|PubMed:20479230, ECO:0000269\|PubMed:26306426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by zinc deficiency. {ECO:0000269\|PubMed:20479230}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023770671.1	0.0	basic leucine zipper 23-like
Swissprot	Q8VY76	1e-102	BZP19_ARATH; Basic leucine zipper 19
TrEMBL	A0A2J6KYT9	0.0	A0A2J6KYT9_LACSA; Uncharacterized protein
STRING	XP_009797256.1	1e-130	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G35040.1	6e-89	bZIP family protein

Publications ? help Back to Top
Azevedo H, et al. Transcriptomic profiling of Arabidopsis gene expression in response to varying micronutrient zinc supply. Genom Data, 2016. 7: p. 256-8 [PMID:26981422] Castro PH, et al. Phylogenetic analysis of F-bZIP transcription factors indicates conservation of the zinc deficiency response across land plants. Sci Rep, 2017. 7(1): p. 3806 [PMID:28630437] Henriques AR,Farias DDR,Costa de Oliveira A Identification and characterization of the bZIP transcription factor involved in zinc homeostasis in cereals. Genet. Mol. Res., 2017. [PMID:28671251] Nazri AZ,Griffin JHC,Peaston KA,Alexander-Webber DGA,Williams LE F-group bZIPs in barley-a role in Zn deficiency. Plant Cell Environ., 2017. 40(11): p. 2754-2770 [PMID:28763829] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]