PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa002056
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family ARF
Protein Properties Length: 655aa    MW: 73583 Da    PI: 6.1405
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58694658PU_refUnigeneView CDS
PUT-187a-Lactuca_sativa-51455PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B371.21.3e-22127227198
                EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..E CS
         B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelv 93 
                f+k+lt sd++++g +++ +++a+++       +++    ++l+  d++g++W +++i+r++++r++lt+GW+ Fv+a++L +gD ++F   + +++el+
  Lsa002056 127 FCKTLTASDTSTHGGFSVLRRHADDClppldmsQQP--PWQELVASDLHGNEWHFRHIFRGQPRRHLLTTGWSVFVSAKKLVAGDAFIFL--RGENGELR 222
                99****************************964333..4459************************************************..449999** PP

                EEEE- CS
         B3  94 vkvfr 98 
                v+v+r
  Lsa002056 223 VGVRR 227
                ***97 PP
2Auxin_resp112.15.5e-37253335183
  Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                 a+ha++t++ F+v+Y+Pr+s+seF+v+++k+++a ++k+svGmRfkm+fe+e+++err+sGt+vgv d+ +++W +S+WrsLk
   Lsa002056 253 ASHAIATGTLFSVFYKPRTSRSEFIVSLNKYLEAQNHKLSVGMRFKMRFEGEEVPERRFSGTIVGVGDTASSKWLDSEWRSLK 335
                 789******************************************************************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.1E-43116256IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.104.0E-39123242IPR015300DNA-binding pseudobarrel domain
CDDcd100171.22E-20125227No hitNo description
SMARTSM010196.8E-21127229IPR003340B3 DNA binding domain
PfamPF023621.1E-20127227IPR003340B3 DNA binding domain
PROSITE profilePS5086311.265127229IPR003340B3 DNA binding domain
PfamPF065073.9E-35253335IPR010525Auxin response factor
PfamPF023091.6E-6531569IPR033389AUX/IAA domain
PROSITE profilePS5174525.683533626IPR000270PB1 domain
SuperFamilySSF542772.55E-10536610No hitNo description
PfamPF023096.5E-6580624IPR033389AUX/IAA domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 655 aa     Download sequence    Send to blast
MAHVAATHFP GGPQSGSSGD AIYKELWHAC AGPLVNVPRE GERVYYFPQG HMEQLEASMH  60
QGLDQQLPSF NLPAKILCKV MNVHLRAEPE TDEVYAQITL LPDTNQNEVT SPDPPLPEPP  120
NCTVHSFCKT LTASDTSTHG GFSVLRRHAD DCLPPLDMSQ QPPWQELVAS DLHGNEWHFR  180
HIFRGQPRRH LLTTGWSVFV SAKKLVAGDA FIFLRGENGE LRVGVRRLMR LLNNMPSSVI  240
SSHSMHLGVL ATASHAIATG TLFSVFYKPR TSRSEFIVSL NKYLEAQNHK LSVGMRFKMR  300
FEGEEVPERR FSGTIVGVGD TASSKWLDSE WRSLKVQWDE PSSILRPDRV SPWELEPLVA  360
SNTSSNPQPP HRNKRARPPV LPSSMPDLST LGMWKPPADR HSAFQYCEPQ RGRDIYPSNN  420
VNSISLSYSE NGSMPPVSTT SIQWSNLREP LTESFEHVAN KENGEKRQSN GYRLFGIELL  480
EHSTVDETSP VGMGMSRGMT EELRICPLDT ESDIPSASCE PEKSSVLHTR QIRSCTKVHM  540
QGIAVGRAVD LTQFNCYEDL LSKLENMFEI EGELREVPKK WQVVYTDVED DIMMVGDDPW  600
HEFCNMVRKI FIYTTEEAKR LSPKIKLPEN DEIIQGKPAQ DSTEEHSSSN EGSGC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A0.043581355Auxin response factor 1
4ldw_A0.043581355Auxin response factor 1
4ldw_B0.043581355Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Acts as repressor of IAA2, IAA3 and IAA7. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16176952}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023730671.10.0auxin response factor 1
SwissprotQ8L7G00.0ARFA_ARATH; Auxin response factor 1
TrEMBLA0A2J6KMK40.0A0A2J6KMK4_LACSA; Auxin response factor
STRINGcassava4.1_002969m0.0(Manihot esculenta)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G59750.40.0auxin response factor 1
Publications ? help Back to Top
  1. Montesinos JC,Pastor-Cantizano N,Robinson DG,Marcote MJ,Aniento F
    Arabidopsis p24δ5 and p24δ9 facilitate Coat Protein I-dependent transport of the K/HDEL receptor ERD2 from the Golgi to the endoplasmic reticulum.
    Plant J., 2014. 80(6): p. 1014-30
    [PMID:25312353]
  2. Marais C, et al.
    The Qb-SNARE Memb11 interacts specifically with Arf1 in the Golgi apparatus of Arabidopsis thaliana.
    J. Exp. Bot., 2015. 66(21): p. 6665-78
    [PMID:26208648]
  3. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  4. Zhang M,Hu X,Zhu M,Xu M,Wang L
    Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis.
    Sci Rep, 2017. 7(1): p. 1395
    [PMID:28469131]