PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa000924
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family WRKY
Protein Properties Length: 402aa    MW: 44373.4 Da    PI: 8.8636
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-187a-Lactuca_sativa-1653PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY103.21.4e-32174230259
                --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
       WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                +DgynWrKYGqK+vkgs++prsYYrCt+++C vkkkvers+ d+ v+ei+Y+g+Hnh+
  Lsa000924 174 EDGYNWRKYGQKQVKGSDYPRSYYRCTHQRCLVKKKVERST-DGLVTEIIYKGQHNHQ 230
                8****************************************.***************8 PP
2WRKY102.13.1e-32309366158
                ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS CS
       WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnh 58 
                ldDgy+WrKYGqK+vkg+ +prsYY+Cts+gC+v+k+ver+a+dpk+v++tYeg+Hnh
  Lsa000924 309 LDDGYKWRKYGQKVVKGNSHPRSYYKCTSKGCKVRKHVERAANDPKAVITTYEGKHNH 366
                59******************************************************** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.808.7E-29167232IPR003657WRKY domain
PROSITE profilePS5081123.812168232IPR003657WRKY domain
SuperFamilySSF1182908.24E-26171232IPR003657WRKY domain
SMARTSM007743.1E-36173231IPR003657WRKY domain
PfamPF031067.4E-25174230IPR003657WRKY domain
Gene3DG3DSA:2.20.25.802.1E-35295367IPR003657WRKY domain
SuperFamilySSF1182902.22E-28302367IPR003657WRKY domain
PROSITE profilePS5081135.358304369IPR003657WRKY domain
SMARTSM007746.1E-37309368IPR003657WRKY domain
PfamPF031061.6E-25310366IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 402 aa     Download sequence    Send to blast
MDEIRRLISS SASFLPPNIS IPATSTVENL FANGSGGGVG ESPGPMTLIS NFLSENDREA  60
DYHSFSQLLA GTMSSSVEIQ GRIPPRDLDA GVSFPENIGG CGGVGRGVDF SPGYFPPAKG  120
SYGTFHQQAL AQAKTKATTH HRLPPSMADQ YVIRPELSIS GSHSQPLTAD KPAEDGYNWR  180
KYGQKQVKGS DYPRSYYRCT HQRCLVKKKV ERSTDGLVTE IIYKGQHNHQ PPRSIGTSGE  240
FEPFKGREDQ ESSHEQSGLN DSDGASDDVA KPQTKKRNVE AREFDPVASH QKSMETRIVV  300
QATSEIDLLD DGYKWRKYGQ KVVKGNSHPR SYYKCTSKGC KVRKHVERAA NDPKAVITTY  360
EGKHNHYVLA NGKNNCELTK ETTSQLKAQD PVGLLRLKDE RI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A9e-36174366877Probable WRKY transcription factor 4
2lex_A9e-36174366877Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023732420.10.0probable WRKY transcription factor 3
SwissprotQ9XI904e-96WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLA0A2J6MCU40.0A0A2J6MCU4_LACSA; Uncharacterized protein
STRINGXP_009794188.11e-113(Nicotiana sylvestris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G03340.13e-91WRKY DNA-binding protein 3
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]