PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Lsa000010 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
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Family | AP2 | ||||||||
Protein Properties | Length: 498aa MW: 54856.1 Da PI: 6.5605 | ||||||||
Description | AP2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | AP2 | 54.3 | 3.4e-17 | 174 | 223 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++g Lsa000010 174 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 223 78*******************......55************************998 PP | |||||||
2 | AP2 | 42.9 | 1.2e-13 | 266 | 316 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV+ +k grW+A+ + +k+++lg f+t+ eAa+a+++a+ k +g Lsa000010 266 SKYRGVTLHK-CGRWEARMGQF--L-GKKYVYLGLFDTEVEAARAYDKAAIKCNG 316 89********.7******5553..2.26**********99**********99776 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Pfam | PF00847 | 2.4E-9 | 174 | 223 | IPR001471 | AP2/ERF domain |
SuperFamily | SSF54171 | 8.5E-16 | 174 | 232 | IPR016177 | DNA-binding domain |
CDD | cd00018 | 6.22E-11 | 175 | 230 | No hit | No description |
PROSITE profile | PS51032 | 17.649 | 175 | 231 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 3.2E-31 | 175 | 237 | IPR001471 | AP2/ERF domain |
Gene3D | G3DSA:3.30.730.10 | 3.1E-17 | 175 | 231 | IPR001471 | AP2/ERF domain |
CDD | cd00018 | 8.73E-25 | 266 | 326 | No hit | No description |
Pfam | PF00847 | 3.2E-9 | 266 | 316 | IPR001471 | AP2/ERF domain |
SuperFamily | SSF54171 | 4.97E-17 | 266 | 326 | IPR016177 | DNA-binding domain |
PROSITE profile | PS51032 | 15.369 | 267 | 324 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 9.6E-31 | 267 | 330 | IPR001471 | AP2/ERF domain |
Gene3D | G3DSA:3.30.730.10 | 1.4E-16 | 267 | 325 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 5.2E-6 | 268 | 279 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 5.2E-6 | 306 | 326 | IPR001471 | AP2/ERF domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 498 aa Download sequence Send to blast |
MWDLNGFPDR RGCSSPVEGD EEDSNNTNKG KGVGSISNSS SSAVVMEEDG GSEEEESERG 60 SPRKRSTTGD GRLFGFSMTE NSSWDSDPPV TRQFFPVDDS EVGPTTSGGV GEGLISPATT 120 FPTAHWFGVK FCHQSSDPLD GVAATADGFL GKTTPAVVPQ PLKKSRRGPR SRSSQYRGVT 180 FYRRTGRWES HIWDCGKQVY LGGFDTAHAA ARAYDRAAIK FRGMEADINF NLEDYEDDVK 240 QMSTLTKEEF VHVLRRQSTG FPRGSSKYRG VTLHKCGRWE ARMGQFLGKK YVYLGLFDTE 300 VEAARAYDKA AIKCNGKAAV TNFDSSIYDN ELNLTECSNN SNKDSNVSSD HNLDLSLGGG 360 SASNTMNEGG ENGHFTRDHH HSDTIQLGFR PSGRNETRTS HFMDHRNLES FNIPNEIRGY 420 KHFMRPVDSS MHNMFDPPIF NSLSHQMQFS SSTMQGGNNL SAASIGENNM NANAPPLHQI 480 YAKSAAASSG FPQQRFNV |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269|PubMed:1675158, ECO:0000269|PubMed:23034631, ECO:0000269|PubMed:7919989}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269|PubMed:12805630, ECO:0000269|PubMed:12893888, ECO:0000269|PubMed:14555699}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_023737726.1 | 0.0 | AP2-like ethylene-responsive transcription factor TOE3 | ||||
Swissprot | P47927 | 1e-120 | AP2_ARATH; Floral homeotic protein APETALA 2 | ||||
TrEMBL | A0A2J6K6S2 | 0.0 | A0A2J6K6S2_LACSA; Uncharacterized protein | ||||
STRING | VIT_07s0031g00220.t01 | 1e-150 | (Vitis vinifera) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT4G36920.2 | 1e-112 | AP2 family protein |