PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lj2g3v2017430.3
Organism
Lotus japonicus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Loteae; Lotus
Family MYB
Protein Properties Length: 143aa    MW: 16867.4 Da    PI: 8.2049
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lj2g3v2017430.3genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding66.25.8e-215197148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     r  WT+eEd ll++ vk++ g++Wk+Ia +++ gRt+ qc +rwqk+l
  Lj2g3v2017430.3 51 RSCWTEEEDNLLIETVKKHDGRSWKKIATYLP-GRTDVQCMHRWQKVL 97
                     678*****************************.************986 PP
2Myb_DNA-binding49.59.7e-16103142141
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqck 41 
                      +g+WT+eEd+ l+++v+++G ++W+ +a+ ++ gR +kqc+
  Lj2g3v2017430.3 103 KGPWTKEEDDCLIELVRKYGLKRWSVVAKFLP-GRIGKQCR 142
                      79******************************.*******9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129426.24646101IPR017930Myb domain
SuperFamilySSF466892.65E-1746100IPR009057Homeodomain-like
SMARTSM007179.1E-175099IPR001005SANT/Myb domain
PfamPF002495.9E-195197IPR001005SANT/Myb domain
CDDcd001677.31E-155497No hitNo description
Gene3DG3DSA:1.10.10.605.1E-2554103IPR009057Homeodomain-like
SuperFamilySSF466897.43E-2283142IPR009057Homeodomain-like
SMARTSM007173.1E-7102143IPR001005SANT/Myb domain
PROSITE profilePS5129420.498102143IPR017930Myb domain
PfamPF002493.2E-15103142IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.7E-20104143IPR009057Homeodomain-like
CDDcd001671.51E-12105143No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 143 aa     Download sequence    Send to blast
MFEVKSELDD FEFDSPRRDL LQLRLYSPNC VSDTSPLETT PDARIKAQVR RSCWTEEEDN  60
LLIETVKKHD GRSWKKIATY LPGRTDVQCM HRWQKVLNPE LVKGPWTKEE DDCLIELVRK  120
YGLKRWSVVA KFLPGRIGKQ CRE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h88_C3e-39471432142MYB PROTO-ONCOGENE PROTEIN
1h89_C3e-39471432142MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in the root quiescent center (PubMed:15937229). Accumulates in division zone of primary root tips and emerging lateral roots. Also present in floral organs in young flower buds. Weakly and uniformly present in the developing embryo and maternal tissues (PubMed:17287251). Expressed specifically in proliferating stage of leaves (PubMed:26069325). {ECO:0000269|PubMed:15937229, ECO:0000269|PubMed:17287251, ECO:0000269|PubMed:26069325}.
UniprotTISSUE SPECIFICITY: Expressed in roots, cotyledons and leaves, especially in vascular tissues, and in flowers. {ECO:0000269|PubMed:17287251}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669, PubMed:25806785). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269|PubMed:17287251, ECO:0000269|PubMed:21862669, ECO:0000269|PubMed:25806785}.; FUNCTION: Involved in transcription regulation during induced endoreduplication at the powdery mildew (e.g. G.orontii) infection site, thus promoting G.orontii growth and reproduction. {ECO:0000269|PubMed:20018666}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLj2g3v2017430.3
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Slightly induced by salicylic acid (SA) (PubMed:16463103). Expressed in a cell cycle-dependent manner, with highest levels 2 hours before the peak of mitotic index in cells synchronized by aphidicolin. Activated by CYCB1 (PubMed:17287251). Accumulates at powdery mildew (e.g. G.orontii) infected cells. {ECO:0000269|PubMed:16463103, ECO:0000269|PubMed:17287251}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAP0061483e-66AP006148.1 Lotus japonicus genomic DNA, chromosome 2, clone: LjT41D09, TM0304, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020217686.15e-65myb-related protein B isoform X2
RefseqXP_027361603.16e-65uncharacterized protein LOC113869477
RefseqXP_027361604.16e-65uncharacterized protein LOC113869477
RefseqXP_027361605.16e-65uncharacterized protein LOC113869477
SwissprotQ94FL93e-40MB3R4_ARATH; Transcription factor MYB3R-4
TrEMBLA0A371GBX91e-70A0A371GBX9_MUCPR; Transcription factor MYB3R-5 (Fragment)
STRINGXP_004511594.11e-60(Cicer arietinum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G11510.11e-42myb domain protein 3r-4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Saito T, et al.
    Genetic interaction between G2/M phase-specific transcription factor MYB3R4 and MAPKKK ANP3 for execution of cytokinesis in Arabidopsis thaliana.
    Plant Signal Behav, 2015. 10(3): p. e990817
    [PMID:25806785]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  4. Chen P, et al.
    Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage.
    Nat Commun, 2017. 8(1): p. 635
    [PMID:28935922]