PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kalax.0952s0003.3.p

Organism

Kalanchoe marnieriana

Taxonomic ID

80907

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

CAMTA

Protein Properties

Length: 1069aa MW: 119313 Da PI: 5.5418

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0952s0003.3.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	179	5.7e-56	21	137	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseen 91 l+ ++rwl++ ei++iL+n++++++ e++++p+sgsl+L++rk++ryfrkDG++w+kkkdgktv+E+he+LK g+v+vl+cyYah+e n Kalax.0952s0003.3.p 21 LEAQHRWLRPAEICEILQNYKSFRICPEPADKPPSGSLFLFDRKVLRYFRKDGHNWRKKKDGKTVKEAHERLKAGSVDVLHCYYAHGEAN 110 5679************************************************************************************ PP CG-1 92 ptfqrrcywlLeeelekivlvhylevk 118 ++fqrr+yw+Lee+l++ivlvhy++vk Kalax.0952s0003.3.p 111 ESFQRRSYWMLEESLSHIVLVHYRDVK 137 **********************985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	82.195	16	142	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	7.2E-78	19	137	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	2.4E-49	22	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF01833	1.4E-4	484	562	IPR002909	IPT domain
SuperFamily	SSF81296	7.0E-17	484	570	IPR014756	Immunoglobulin E-set
CDD	cd00204	4.61E-13	668	776	No hit	No description
Gene3D	G3DSA:1.25.40.20	2.0E-16	674	779	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50297	16.547	675	788	IPR020683	Ankyrin repeat-containing domain
SuperFamily	SSF48403	3.58E-17	675	779	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	3.0E-6	689	779	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50088	9.324	717	749	IPR002110	Ankyrin repeat
SMART	SM00248	0.22	717	746	IPR002110	Ankyrin repeat
SMART	SM00248	800	756	785	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	3.72E-7	849	938	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	17	887	909	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.73	890	917	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.0018	890	908	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.012	910	932	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.176	911	935	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	5.6E-4	913	932	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1069 aa Download sequence Send to blast
MDSNSRRHVL GNQLDIEQIL LEAQHRWLRP AEICEILQNY KSFRICPEPA DKPPSGSLFL 60 FDRKVLRYFR KDGHNWRKKK DGKTVKEAHE RLKAGSVDVL HCYYAHGEAN ESFQRRSYWM 120 LEESLSHIVL VHYRDVKGNR TSISRTRENV ERSHAAWEAG DNLSESEISN SASSSMQRSS 180 YQNHSPTIDT SLSSMHASQY EDAESAYNDL NSSGHHSLFE VQTHVNGNLV GSSNTYYTVS 240 NYQDKRSDYG GVDITSLTRA GTSEDGAGLG YERQKHNDFP SWEHVLKNCA GEIPSMGFES 300 SLLSARPDNT GNIFKQESHK LGQLMTDGFT NKQEIASDVQ YQGEWLTSDG FSSDLSKWPL 360 DIEYNSNADG QETGSLNLLG SMESSHSHPN EPDEPPKLEP QGMKHPLLQG PVNEDGLRKL 420 DSFNRWMSKE LGDVDDSIVQ SSSGAYWSAV ESENVIDDSG SGSQGHLDAD MVGPSLSMDQ 480 LFSIIDFSPN WAYEDSEIKV LITGKFLKGQ SEVEKLKWSC MFGEIEVPAE VIADGVLRCL 540 APYHKYGRVP FYVTCSNRFA CSEVREFEFR AHPVQGSVDA DASKDQEIIF HMRLLKLLSL 600 GLDPPDYDSK VPGDNSSLSA KISDLMNEDE DEWDQMLKTP SAENFPSERM KDQLIQKLLK 660 EKLHVWLLHK ASEGGKGANV LDEDGQGVLH LAAALGYGWA IPPTILAGVN INFRDVNGWT 720 ALHWAAFCGR ERTVASLISL GAAAGALTDP TPKYPSGRTA ADLASMNRHK GIAGYLAENA 780 LAAHLISLDL KDPVASDAVD VSGVKAVQAV AERDANPITD SHIPYISLKD SLTAVCNATQ 840 AAARITQVFR AQSFQRKQVQ EYEDNERSSE AALSHIALKQ QNSFHGGPVD AATRIQKNYR 900 SYKGRKEYLI IRQRIVKLQA HVRGHQVRKN YRKFIWSVGI LEKVILRWRR KGSGLRGFKP 960 EGQIEGATSN TSLSKEDDYD FFKEGRKQTE ERLQKALARV KSMVQYPESR AQYQRLLNVV 1020 SEIEETKGAY DRALNAGADE MADFDDDLID LEALLDADEI DSLMMAES*

Sequence ? help Back to Top

Protein Sequence Length: 1069 aa Download sequence Send to blast

MDSNSRRHVL GNQLDIEQIL LEAQHRWLRP AEICEILQNY KSFRICPEPA DKPPSGSLFL  60
FDRKVLRYFR KDGHNWRKKK DGKTVKEAHE RLKAGSVDVL HCYYAHGEAN ESFQRRSYWM  120
LEESLSHIVL VHYRDVKGNR TSISRTRENV ERSHAAWEAG DNLSESEISN SASSSMQRSS  180
YQNHSPTIDT SLSSMHASQY EDAESAYNDL NSSGHHSLFE VQTHVNGNLV GSSNTYYTVS  240
NYQDKRSDYG GVDITSLTRA GTSEDGAGLG YERQKHNDFP SWEHVLKNCA GEIPSMGFES  300
SLLSARPDNT GNIFKQESHK LGQLMTDGFT NKQEIASDVQ YQGEWLTSDG FSSDLSKWPL  360
DIEYNSNADG QETGSLNLLG SMESSHSHPN EPDEPPKLEP QGMKHPLLQG PVNEDGLRKL  420
DSFNRWMSKE LGDVDDSIVQ SSSGAYWSAV ESENVIDDSG SGSQGHLDAD MVGPSLSMDQ  480
LFSIIDFSPN WAYEDSEIKV LITGKFLKGQ SEVEKLKWSC MFGEIEVPAE VIADGVLRCL  540
APYHKYGRVP FYVTCSNRFA CSEVREFEFR AHPVQGSVDA DASKDQEIIF HMRLLKLLSL  600
GLDPPDYDSK VPGDNSSLSA KISDLMNEDE DEWDQMLKTP SAENFPSERM KDQLIQKLLK  660
EKLHVWLLHK ASEGGKGANV LDEDGQGVLH LAAALGYGWA IPPTILAGVN INFRDVNGWT  720
ALHWAAFCGR ERTVASLISL GAAAGALTDP TPKYPSGRTA ADLASMNRHK GIAGYLAENA  780
LAAHLISLDL KDPVASDAVD VSGVKAVQAV AERDANPITD SHIPYISLKD SLTAVCNATQ  840
AAARITQVFR AQSFQRKQVQ EYEDNERSSE AALSHIALKQ QNSFHGGPVD AATRIQKNYR  900
SYKGRKEYLI IRQRIVKLQA HVRGHQVRKN YRKFIWSVGI LEKVILRWRR KGSGLRGFKP  960
EGQIEGATSN TSLSKEDDYD FFKEGRKQTE ERLQKALARV KSMVQYPESR AQYQRLLNVV  1020
SEIEETKGAY DRALNAGADE MADFDDDLID LEALLDADEI DSLMMAES*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2cxk_A	1e-13	484	576	9	95	calmodulin binding transcription activator 1
2cxk_B	1e-13	484	576	9	95	calmodulin binding transcription activator 1
2cxk_C	1e-13	484	576	9	95	calmodulin binding transcription activator 1
2cxk_D	1e-13	484	576	9	95	calmodulin binding transcription activator 1
2cxk_E	1e-13	484	576	9	95	calmodulin binding transcription activator 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010645223.1	0.0	PREDICTED: calmodulin-binding transcription activator 3 isoform X3
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A2R6RDE6	0.0	A0A2R6RDE6_ACTCH; Calmodulin-binding transcription activator 3 like
STRING	VIT_07s0141g00250.t01	0.0	(Vitis vinifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Link Out ? help Back to Top
Phytozome	Kalax.0952s0003.3.p

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]