PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kalax.0801s0006.2.p
Organism
Kalanchoe marnieriana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family ARF
Protein Properties Length: 851aa    MW: 94792.8 Da    PI: 6.3262
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kalax.0801s0006.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B372.17.2e-23155256199
                          EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE CS
                   B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkl 84 
                          f+k+lt sd++++g +++ +++a+e+      + k++ +++l+ +d++  +W++++i+r++++r++l++GW+ Fv++++L +gD ++F  
  Kalax.0801s0006.2.p 155 FCKTLTASDTSTHGGFSVLRRHADEClppldmS-KQPPTQELVAKDLHKTEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFL- 242
                          99*****************************63.4445569************************************************. PP

                          -SSSEE..EEEEE-S CS
                   B3  85 dgrsefelvvkvfrk 99 
                           + +++el+v+v+r+
  Kalax.0801s0006.2.p 243 -RGENGELRVGVRRA 256
                          .449999*****996 PP
2Auxin_resp118.74.6e-39281363183
           Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                          a+ha+st+++F+v+Y+Pr+s++eF+v++e++++++k+++s+GmRfkm+fe+e+++e+r++G++vg++d+dp rW++SkWr+Lk
  Kalax.0801s0006.2.p 281 AWHAISTGTMFTVFYKPRTSPTEFIVPFEQYMESVKNNYSIGMRFKMRFEGEEAPEQRFTGIIVGTEDADPKRWRDSKWRCLK 363
                          89*******************************************************************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.106.1E-41151270IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019362.49E-40151284IPR015300DNA-binding pseudobarrel domain
CDDcd100174.11E-20153255No hitNo description
SMARTSM010199.6E-22155257IPR003340B3 DNA binding domain
PfamPF023621.1E-20155256IPR003340B3 DNA binding domain
PROSITE profilePS5086311.209155257IPR003340B3 DNA binding domain
PfamPF065073.6E-36281363IPR010525Auxin response factor
PROSITE profilePS5174523.582731824IPR000270PB1 domain
SuperFamilySSF542771.05E-10733808No hitNo description
PfamPF023097.3E-8775822IPR033389AUX/IAA domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0009737Biological Processresponse to abscisic acid
GO:0009911Biological Processpositive regulation of flower development
GO:0010047Biological Processfruit dehiscence
GO:0010150Biological Processleaf senescence
GO:0010227Biological Processfloral organ abscission
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0048481Biological Processplant ovule development
GO:0005634Cellular Componentnucleus
GO:0005515Molecular Functionprotein binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 851 aa     Download sequence    Send to blast
MATSEVRNGN LNARGESHTS GYSEPNGAVA SRNLAEGVGD GRVDAEDALY TELWHACAGP  60
LVTVPRQGDR VFYFPQGHIE QVEASTNKVA DQEMPVYNLP SKILCRVLDV RLMAEPVTDE  120
VFAQVILVPE NYQDENTVEK DPPPPPKPRF HVHSFCKTLT ASDTSTHGGF SVLRRHADEC  180
LPPLDMSKQP PTQELVAKDL HKTEWRFRHI FRGQPRRHLL QSGWSVFVSS KRLVAGDAFI  240
FLRGENGELR VGVRRAMRQQ GNVPSSVISS HSMHLGVLAS AWHAISTGTM FTVFYKPRTS  300
PTEFIVPFEQ YMESVKNNYS IGMRFKMRFE GEEAPEQRFT GIIVGTEDAD PKRWRDSKWR  360
CLKVRWDETS TIPRPDRVSP WKIEPALTPP ALNPIPTPRP KRPRTSVLPL SPDSSVLTRE  420
GSSKVALDPP STNEFLRLVQ GQDISTFRAN LAESNESEIV EKPGMLGIPV DEGRANVVST  480
PRRYHVENLL PLPRHETTYT DLLSGLGSGV DSSNGYCLPF HDSTAATSYM KKYSFEDDVF  540
HKPKNHWSVR PPGGLSLQPP ESSSKYPEQC AYSLYQGGGS TVCGALEGRP MVYGLSTEHR  600
SASLFMPPPK TSYLTNFEWY RNPDPTTSSV QQLETAKPTD GSYKLFGIPL FGHQVSSEPS  660
MSGMNCADKA LEGINHLSPE LCLVDSGPKC GHPEDSDARD FLAVAEQDKT SQYCQPISRE  720
IHGKIQSGST RSCTKVHKQG IALGRSVDLS KFNNYEELKV ELDKLFEFGG ELLATRSNWL  780
VVYTDDEGDM MLVGDDPWQE FCGMVRKIFI YTKDEVQKMN PRTLGCSKIE ENPSSADHLD  840
AVEVDISHSL *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-173293851354Auxin response factor 1
4ldw_A1e-173293851354Auxin response factor 1
4ldw_B1e-173293851354Auxin response factor 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1399405PKRPRTS
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs) (By similarity). Could act as transcriptional activator or repressor (PubMed:26959229, PubMed:26716451, PubMed:27645097, PubMed:28167023). Involved in the control of fruit ripening process (PubMed:26959229, PubMed:26716451, PubMed:28167023). Regulates expression of a number of ripening regulators, transcription factors, and ethylene biosynthesis and signaling components (PubMed:26959229, PubMed:26716451). May act as a transcriptional repressor of auxin-responsive genes (PubMed:26716451). Regulates vegetative growth, lateral root formation and flower organ senescence, possibly partially by regulating gene expression of auxin and ethylene response factor (ERF) genes (PubMed:28167023). Plays a negative role in axillary shoot meristem formation (PubMed:27645097). {ECO:0000255|RuleBase:RU004561, ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229, ECO:0000269|PubMed:27645097, ECO:0000269|PubMed:28167023}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00574DAPTransfer from AT5G62000Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tomato fruit ripening. Expression in tomato fruits is up-regulated by exogenous application of ethylene and down-regulated by inhibition of ethylene receptors with 1-methylcyclopropene (1-MCP) (PubMed:26959229, PubMed:26716451). Up-regulated by plant hormone abscisic acid (ABA) in tomato fruits (PubMed:26959229). Expression is not up-regulated by plant hormone auxin in tomato fruits (PubMed:26716451). Up-regulated by auxin and gibberellic acid (GA), and down-regulated by ethylene in seedlings (PubMed:28167023). Down-regulated during decapitation-induced axillary shoot development and by excision of immature leaves. Down-regulation is inhibited by the application of auxin on the cut surface (PubMed:27645097). {ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229, ECO:0000269|PubMed:27645097, ECO:0000269|PubMed:28167023}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002284543.10.0PREDICTED: auxin response factor 2
SwissprotQ2LAJ30.0ARF2A_SOLLC; Auxin response factor 2A
TrEMBLD7SH690.0D7SH69_VITVI; Auxin response factor
STRINGVIT_17s0000g00320.t010.0(Vitis vinifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Breitel DA, et al.
    AUXIN RESPONSE FACTOR 2 Intersects Hormonal Signals in the Regulation of Tomato Fruit Ripening.
    PLoS Genet., 2016. 12(3): p. e1005903
    [PMID:26959229]
  3. Xu T, et al.
    SlARF2a plays a negative role in mediating axillary shoot formation.
    Sci Rep, 2016. 6: p. 33728
    [PMID:27645097]
  4. Ren Z,Liu R,Gu W,Dong X
    The Solanum lycopersicum auxin response factor SlARF2 participates in regulating lateral root formation and flower organ senescence.
    Plant Sci., 2017. 256: p. 103-111
    [PMID:28167023]