PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kalax.0757s0004.12.p
Organism
Kalanchoe marnieriana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family MYB
Protein Properties Length: 470aa    MW: 53150.5 Da    PI: 6.0861
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kalax.0757s0004.12.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding39.99.5e-132267348
                          SS-HHHHHHHHHHHHHTTTT.-HHHHHHHHTTTS-HHHHHHHHHHHT CS
       Myb_DNA-binding  3 rWTteEdellvdavkqlGgg.tWktIartmgkgRtlkqcksrwqkyl 48
                           WT+eEd++l + ++ +G++ +W+ +a+++   +t  qc+ rw++yl
  Kalax.0757s0004.12.p 22 VWTQEEDDILREQIRIYGTDnSWAIVASKFS-DKTTRQCRRRWYTYL 67
                          6******************************.*************97 PP
2Myb_DNA-binding47.93e-1573116146
                           TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
       Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                           +g WT+eEd ll +a +++G++ W+ Ia+++  gRt++ +k+r+ +
  Kalax.0757s0004.12.p  73 KGGWTPEEDMLLCEAQRKFGNK-WTEIAKMVS-GRTDNAVKNRFST 116
                           688*******************.*********.**********976 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129412.3551567IPR017930Myb domain
SMARTSM007171.3E-121969IPR001005SANT/Myb domain
CDDcd001673.81E-112367No hitNo description
PfamPF139212.2E-142384No hitNo description
Gene3DG3DSA:1.10.10.601.4E-192375IPR009057Homeodomain-like
SuperFamilySSF466894.87E-2647127IPR009057Homeodomain-like
PROSITE profilePS5129421.11268122IPR017930Myb domain
SMARTSM007173.5E-1572120IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.603.6E-2076121IPR009057Homeodomain-like
CDDcd001679.91E-1176117No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 470 aa     Download sequence    Send to blast
MKKRSDINTV EGVKLKERHI VVWTQEEDDI LREQIRIYGT DNSWAIVASK FSDKTTRQCR  60
RRWYTYLNSD FKKGGWTPEE DMLLCEAQRK FGNKWTEIAK MVSGRTDNAV KNRFSTLCKK  120
RAKREALAKE DNISLSNVGK KRILLKSEVG VQENEAPYKK MRRTHIPVPA ESCNREKVVP  180
GEYEKSVQNQ LRPPLAALVK NSVSVGNLLN RRHIPIPKES IHDGHDYYDE DSSLAKDDTE  240
GAALMRQAES FTSLAVRANA QNTEHSLEHA WKVLRELLSQ TKDGDLLRCN ISDVNFQLEE  300
FKNLLQDFKN REEGMRQPDL YEESSGSSDY STGSTLLSHA TEGTPINHPM DTSELNQDMG  360
SEIQVTPGQK ENEESMTMFG SLSYQDGFQS SQEPNGEEVV SAESAVEFGS PLHVTPLFPD  420
ESTEIPSPKF SESERNFLIK ALGMEAPYHP GTNLSQPHPI CKRALLHSL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A1e-242312210108B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds to DNA in promoters cis-regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre-replication complex (PubMed:20675570, PubMed:24687979). Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7) (PubMed:26578169). Together with FAMA and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, specifically required for the last guard mother cells (GMC) symmetric divisions in the stomatal pathway (PubMed:20675570, PubMed:24687979). Represses CYCA2-3 in newly formed guard cells (PubMed:21772250). Together with MYB88, regulates stomata spacing by restricting divisions late in the stomatal cell lineage thus limiting the number of GMC divisions (PubMed:16155180). In collaboration with CDKB1-1 and CDKB1-2, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248). Involved in sensing and/or transducing abiotic stress (e.g. drought and salt), probably via the positive regulation of NAC019 (PubMed:21105921). Regulates female reproduction being required for entry into megasporogenesis, probably via the regulation of cell cycle genes (PubMed:22915737). Plays a minor role in lateral roots (LRs) initiation (PubMed:26578065). Involved complementarily in establishing the gravitropic set-point angles of lateral roots by regulating the transcription of PIN3 and PIN7 in gravity-sensing cells of primary and lateral roots (PubMed:26578169). {ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:20675570, ECO:0000269|PubMed:21105921, ECO:0000269|PubMed:21772250, ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:24123248, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24687979, ECO:0000269|PubMed:26578065, ECO:0000269|PubMed:26578169}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010652303.11e-162PREDICTED: uncharacterized protein LOC100246639 isoform X2
SwissprotF4IRB41e-132MYB88_ARATH; Transcription factor MYB88
TrEMBLA0A2I4EE771e-160A0A2I4EE77_JUGRE; myb-like protein Q isoform X3
TrEMBLA0A2I4EE801e-160A0A2I4EE80_JUGRE; transcription factor MYB36-like isoform X1
STRINGVIT_01s0026g01910.t011e-159(Vitis vinifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G02820.21e-120myb domain protein 88
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Yang K, et al.
    Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.
    J. Exp. Bot., 2014. 65(9): p. 2449-61
    [PMID:24687979]
  4. Yang M
    The FOUR LIPS (FLP) and MYB88 genes conditionally suppress the production of nonstomatal epidermal cells in Arabidopsis cotyledons.
    Am. J. Bot., 2016. 103(9): p. 1559-66
    [PMID:27620181]
  5. Xu Z, et al.
    DGE-seq analysis of MUR3-related Arabidopsis mutants provides insight into how dysfunctional xyloglucan affects cell elongation.
    Plant Sci., 2017. 258: p. 156-169
    [PMID:28330559]
  6. Qu Y, et al.
    Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis.
    J. Exp. Bot., 2017. 68(17): p. 4851-4867
    [PMID:28992128]
  7. Xie Y, et al.
    An atypical R2R3 MYB transcription factor increases cold hardiness by CBF-dependent and CBF-independent pathways in apple.
    New Phytol., 2018. 218(1): p. 201-218
    [PMID:29266327]