PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kalax.0219s0038.6.p

Organism

Kalanchoe marnieriana

Taxonomic ID

80907

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

CAMTA

Protein Properties

Length: 1059aa MW: 118267 Da PI: 5.6659

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0219s0038.6.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	180	2.9e-56	21	137	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseen 91 l+ ++rwl++ ei++iL+n++++++ e++++p+sgsl+L++rk++ryfrkDG++w+kkkdgktv+E+he+LK g+v+vl+cyYah+e+n Kalax.0219s0038.6.p 21 LEAQHRWLRPAEICEILQNYKSFRICPEPADQPPSGSLFLFDRKVLRYFRKDGHNWRKKKDGKTVKEAHERLKAGSVDVLHCYYAHGEDN 110 5679************************************************************************************ PP CG-1 92 ptfqrrcywlLeeelekivlvhylevk 118 ++fqrr+yw+Lee+l++ivlvhy++vk Kalax.0219s0038.6.p 111 ENFQRRSYWMLEEALSHIVLVHYRDVK 137 **********************985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	82.901	16	142	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	1.5E-79	19	137	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	1.0E-49	22	136	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:2.60.40.10	5.4E-5	467	555	IPR013783	Immunoglobulin-like fold
Pfam	PF01833	1.6E-5	468	553	IPR002909	IPT domain
SuperFamily	SSF81296	3.73E-17	468	554	IPR014756	Immunoglobulin E-set
CDD	cd00204	2.24E-14	652	756	No hit	No description
Gene3D	G3DSA:1.25.40.20	4.3E-19	652	765	IPR020683	Ankyrin repeat-containing domain
SuperFamily	SSF48403	2.49E-18	656	763	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50297	18.324	659	772	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	1.6E-8	673	763	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	0.066	701	730	IPR002110	Ankyrin repeat
PROSITE profile	PS50088	9.591	701	733	IPR002110	Ankyrin repeat
SMART	SM00248	250	740	769	IPR002110	Ankyrin repeat
SMART	SM00015	15	873	895	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.309	876	903	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.0035	876	894	IPR000048	IQ motif, EF-hand binding site
SuperFamily	SSF52540	1.27E-5	876	924	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	0.029	896	918	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	8.498	897	921	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	6.5E-4	899	917	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 1059 aa Download sequence Send to blast
MDSSSRRHDL GNQLDIEQIL LEAQHRWLRP AEICEILQNY KSFRICPEPA DQPPSGSLFL 60 FDRKVLRYFR KDGHNWRKKK DGKTVKEAHE RLKAGSVDVL HCYYAHGEDN ENFQRRSYWM 120 LEEALSHIVL VHYRDVKGNR TSISRTRENV ESSITVQEAG DNLSESEISN SASSNMQRSS 180 YQNPSPTTDT SLSSMHASQY EDAESAYNDQ SMCGLHSFLE MRQPANGNLV GPSNTYYTIS 240 SLVYEPQKQN DFPSWEDVLK NCAAENPYMT LGSSRLSAKP DNMGIIFKHE SNMFGHFVTD 300 GFSNKLDIAS DIQGQTEWRY HQASDGSSSD LSKWPLDTKF NSNFDRQDIG SLNLLGSMES 360 SHSQLNEGDG PPKSEPHVPT LDSGLYSDGK GVMKPLHEDG LRKLDSFNRW MSKELGDVDE 420 SIVQTGSGAY WSAVESENAI DDSGSSSHGH MDADMVLPSL STDQLFSIID FSPNWAYEDS 480 EIKVLITGKF LRGQNEVEKL KWSCMFGEVE VPAEVIADGV LRCKAPHHKY GRVPFYVTCS 540 NRFACSEVRE FEYREHPVQQ MDDTDAGTEQ EIFLRMRLLN LLSLGLDPPD YDFKVPGDSS 600 NLIVKISELM NEDNGEWDQT LKTKPAEKFS SEKMNDQLIQ KLLKEKLHVW LLHKAAEGGK 660 GANLPDEDGQ GVLHLAAALG YGWAIPPTIL AGVNINFRDV NGWTALHWAA SCGRERTVAS 720 LISLGAAAGA LTDPTPKYTS GRTAADLAAQ NGHKGIAGYL AEAALAAHLQ SLDLKDPVAG 780 DVVDELGAKA VQAVALRDAN PISDSHIPET VSLRYSIAAV CNATQAAARI TQVFRAQSFQ 840 RKQIQEYEED EHSSHGAALS QIALKQQNAF YGGPVAAATR IQKNYRSYKG RKEFLIIRQR 900 IVKLQAHVRG HQVRKNYGKI IWSVGIVEKV IMRWRRKGSG LRGYKPKGQI EGATSNTSSS 960 TEDDFDFLKE GRKQTEDRLQ KALARVKSMV QYPEARDQYR RLLNVVSEIQ ETKGVYDQAH 1020 TQPDEMADSD DDLIDLEALL EADDMDTLTM QNFKPPPA*

Sequence ? help Back to Top

Protein Sequence Length: 1059 aa Download sequence Send to blast

MDSSSRRHDL GNQLDIEQIL LEAQHRWLRP AEICEILQNY KSFRICPEPA DQPPSGSLFL  60
FDRKVLRYFR KDGHNWRKKK DGKTVKEAHE RLKAGSVDVL HCYYAHGEDN ENFQRRSYWM  120
LEEALSHIVL VHYRDVKGNR TSISRTRENV ESSITVQEAG DNLSESEISN SASSNMQRSS  180
YQNPSPTTDT SLSSMHASQY EDAESAYNDQ SMCGLHSFLE MRQPANGNLV GPSNTYYTIS  240
SLVYEPQKQN DFPSWEDVLK NCAAENPYMT LGSSRLSAKP DNMGIIFKHE SNMFGHFVTD  300
GFSNKLDIAS DIQGQTEWRY HQASDGSSSD LSKWPLDTKF NSNFDRQDIG SLNLLGSMES  360
SHSQLNEGDG PPKSEPHVPT LDSGLYSDGK GVMKPLHEDG LRKLDSFNRW MSKELGDVDE  420
SIVQTGSGAY WSAVESENAI DDSGSSSHGH MDADMVLPSL STDQLFSIID FSPNWAYEDS  480
EIKVLITGKF LRGQNEVEKL KWSCMFGEVE VPAEVIADGV LRCKAPHHKY GRVPFYVTCS  540
NRFACSEVRE FEYREHPVQQ MDDTDAGTEQ EIFLRMRLLN LLSLGLDPPD YDFKVPGDSS  600
NLIVKISELM NEDNGEWDQT LKTKPAEKFS SEKMNDQLIQ KLLKEKLHVW LLHKAAEGGK  660
GANLPDEDGQ GVLHLAAALG YGWAIPPTIL AGVNINFRDV NGWTALHWAA SCGRERTVAS  720
LISLGAAAGA LTDPTPKYTS GRTAADLAAQ NGHKGIAGYL AEAALAAHLQ SLDLKDPVAG  780
DVVDELGAKA VQAVALRDAN PISDSHIPET VSLRYSIAAV CNATQAAARI TQVFRAQSFQ  840
RKQIQEYEED EHSSHGAALS QIALKQQNAF YGGPVAAATR IQKNYRSYKG RKEFLIIRQR  900
IVKLQAHVRG HQVRKNYGKI IWSVGIVEKV IMRWRRKGSG LRGYKPKGQI EGATSNTSSS  960
TEDDFDFLKE GRKQTEDRLQ KALARVKSMV QYPEARDQYR RLLNVVSEIQ ETKGVYDQAH  1020
TQPDEMADSD DDLIDLEALL EADDMDTLTM QNFKPPPA*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2cxk_A	1e-13	468	557	9	92	calmodulin binding transcription activator 1
2cxk_B	1e-13	468	557	9	92	calmodulin binding transcription activator 1
2cxk_C	1e-13	468	557	9	92	calmodulin binding transcription activator 1
2cxk_D	1e-13	468	557	9	92	calmodulin binding transcription activator 1
2cxk_E	1e-13	468	557	9	92	calmodulin binding transcription activator 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010645223.1	0.0	PREDICTED: calmodulin-binding transcription activator 3 isoform X3
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A2R6RDE6	0.0	A0A2R6RDE6_ACTCH; Calmodulin-binding transcription activator 3 like
STRING	XP_006428204.1	0.0	(Citrus clementina)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Link Out ? help Back to Top
Phytozome	Kalax.0219s0038.6.p

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]