PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kalax.0180s0026.1.p
Organism
Kalanchoe marnieriana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family HD-ZIP
Protein Properties Length: 723aa    MW: 78927.6 Da    PI: 6.2364
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kalax.0180s0026.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.64.9e-192071556
                         SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
             Homeobox  5 ttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                         ++++++q+++Le++F++++++++++r +L+++lgL  rq+k+WFqNrR+++k
  Kalax.0180s0026.1.p 20 HRHSAHQIQRLEAVFKECPHLDEKQRLQLSRELGLAPRQIKFWFQNRRTQMK 71
                         6799*********************************************998 PP
2START165.34.3e-522284521206
                          HHHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S... CS
                START   1 elaeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla... 77 
                          e+a  a+++lvk+  a+ep+W+ks+    + +n++ +l   +++ +       ++ea+r+s+vv m++ llv  ++d + +W et+    
  Kalax.0180s0026.1.p 228 EIAANAMNDLVKLFHATEPLWTKSAtdgrDTLNYENYLMLSPRASNhlkkpnARTEASRDSAVVAMNSLLLVDMFMDAG-KWLETFSpiv 316
                          578899***********************99****9999998887799*9*9***************************.********** PP

                          .EEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECT CS
                START  78 .kaetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksn 159
                           +a+t++v++ g      g+l lm+ elq+lsplvp R+fvf+Ry++q ++g+wvivdvS d  + +     +  +++lpSg+lie++sn
  Kalax.0180s0026.1.p 317 sAAKTIQVLTAGvsgslsGTLRLMYEELQVLSPLVPtREFVFLRYCQQTEKGSWVIVDVSCDFANGNCH--VLPQSRRLPSGCLIEDMSN 404
                          ******************************************************************975..6666677************ PP

                          CEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
                START 160 ghskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                          g skv wvehv+ ++ +  + l+  l+ksg+a+ga +w+atlqr ce+
  Kalax.0180s0026.1.p 405 GISKVSWVEHVEIQDDSQaDHLYGDLIKSGYAFGAERWLATLQRMCER 452
                          *************998888***************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466892.69E-19876IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.2E-20980IPR009057Homeodomain-like
PROSITE profilePS5007116.8921373IPR001356Homeobox domain
SMARTSM003891.7E-181477IPR001356Homeobox domain
CDDcd000862.09E-181573No hitNo description
PfamPF000461.4E-162071IPR001356Homeobox domain
PROSITE patternPS0002704871IPR017970Homeobox, conserved site
PROSITE profilePS5084844.843219455IPR002913START domain
SuperFamilySSF559617.25E-34220454No hitNo description
CDDcd088751.66E-105223451No hitNo description
PfamPF018522.7E-44228452IPR002913START domain
SMARTSM002348.2E-44228452IPR002913START domain
Gene3DG3DSA:3.30.530.201.1E-6290415IPR023393START-like domain
SuperFamilySSF559611.01E-17475700No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 723 aa     Download sequence    Send to blast
MEQGSAGDDS DPQKRKKRFH RHSAHQIQRL EAVFKECPHL DEKQRLQLSR ELGLAPRQIK  60
FWFQNRRTQM KGQLERADNS ILKAENDKIR CSNIALREAL KNIMCPNCGS MRIGDDPYLD  120
EQQLQLENAH LKEELDRVSS IAAKYIGRPV SQFSTTQSSH LSLIELSLGS FGGQIIPSPS  180
LGGFGSHGIT GSSLELDILS GTSSSVPPTM EIQPGSTIND MDKTLMAEIA ANAMNDLVKL  240
FHATEPLWTK SATDGRDTLN YENYLMLSPR ASNHLKKPNA RTEASRDSAV VAMNSLLLVD  300
MFMDAGKWLE TFSPIVSAAK TIQVLTAGVS GSLSGTLRLM YEELQVLSPL VPTREFVFLR  360
YCQQTEKGSW VIVDVSCDFA NGNCHVLPQS RRLPSGCLIE DMSNGISKVS WVEHVEIQDD  420
SQADHLYGDL IKSGYAFGAE RWLATLQRMC ERYASLTVSG TNIHDLDGVI PTFDGKANMM  480
KLSQRMVSNF CATVSTSTNS QQCTTLAGSN ESQVRLTVRK TATDPGQPNG LVLCAATSIW  540
LPVSPQNAFN FFRDVSMRPQ WDVLSKGGAV QEVAHISCGS HPGNYISILR ASDPSQNNMV  600
ILQECCIDSW GSLIVYSPVE IPEINMAVSG GDPSCIPLLP SGFMISPDGR SEIAHLSEAS  660
STSSSRHSTM TKSSGSLITI GFQILAGSSP VAKLDMESVT TVNNLIGMTI HQIKAALDCP  720
DS*
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017973835.10.0PREDICTED: homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A2N9ELU80.0A0A2N9ELU8_FAGSY; Uncharacterized protein
TrEMBLA0A438HFQ00.0A0A438HFQ0_VITVI; Homeobox-leucine zipper protein HDG11
STRINGXP_010099679.10.0(Morus notabilis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]