PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kalax.0090s0054.1.p

Organism

Kalanchoe marnieriana

Taxonomic ID

80907

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

E2F/DP

Protein Properties

Length: 443aa MW: 48640.7 Da PI: 4.881

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0090s0054.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	86.7	1.8e-27	130	195	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++++giv+ln++a+ L +v ++RRiYDi+NVLe+++liek+ kn+irwkg Kalax.0090s0054.1.p 130 RYDSSLGLLTKKFISLIKQAKDGIVDLNKAADML---EV--QKRRIYDITNVLEGIGLIEKMLKNQIRWKG 195 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.4E-28	127	196	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.4E-34	130	195	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	3.67E-17	130	193	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	2.7E-24	132	195	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	1.10E-34	206	312	No hit	No description
SuperFamily	SSF144074	3.92E-24	210	312	No hit	No description
Pfam	PF16421	7.1E-25	212	310	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 443 aa Download sequence Send to blast
MLESAPSSQR PNRQQILSSA KPPSGDSYYT FSSVSCKSRR LADRGEDGVV VRSLLYREKD 60 TKESEAQISR VAVGGSLKTS RSSASMLKSG KGDKASKTRV VKSGGPGPRT PASDVGLPLV 120 NNLSAANSCR YDSSLGLLTK KFISLIKQAK DGIVDLNKAA DMLEVQKRRI YDITNVLEGI 180 GLIEKMLKNQ IRWKGIDVSK PGVCNESVGS IQGDIETISS EEHKLDEKIS EMQGKLTDLF 240 EDENKKKWLF LRDEEIMTLP CFQNETLIAV KAPHGATVEV PDPDEDGDHS EKRYRILFRS 300 IMGPIDVYLV SQFEEKVEEV YGNGETSSIQ TASKIDTPPR NTITDERIHD DPQIYSDLNT 360 LPDVGGIKKI VPSEVDNDAD YWLLSEADVS ITDMWSTEDC PGLNGSGFDT WRPDLASSEQ 420 PLPPTGTTPK AKRALFASNS DM*

Sequence ? help Back to Top

Protein Sequence Length: 443 aa Download sequence Send to blast

MLESAPSSQR PNRQQILSSA KPPSGDSYYT FSSVSCKSRR LADRGEDGVV VRSLLYREKD  60
TKESEAQISR VAVGGSLKTS RSSASMLKSG KGDKASKTRV VKSGGPGPRT PASDVGLPLV  120
NNLSAANSCR YDSSLGLLTK KFISLIKQAK DGIVDLNKAA DMLEVQKRRI YDITNVLEGI  180
GLIEKMLKNQ IRWKGIDVSK PGVCNESVGS IQGDIETISS EEHKLDEKIS EMQGKLTDLF  240
EDENKKKWLF LRDEEIMTLP CFQNETLIAV KAPHGATVEV PDPDEDGDHS EKRYRILFRS  300
IMGPIDVYLV SQFEEKVEEV YGNGETSSIQ TASKIDTPPR NTITDERIHD DPQIYSDLNT  360
LPDVGGIKKI VPSEVDNDAD YWLLSEADVS ITDMWSTEDC PGLNGSGFDT WRPDLASSEQ  420
PLPPTGTTPK AKRALFASNS DM*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	5e-24	130	196	7	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017609642.1	1e-145	PREDICTED: transcription factor E2FB-like
Swissprot	Q9FV71	1e-116	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A0B0N9E2	1e-143	A0A0B0N9E2_GOSAR; Transcription factor E2FB-like protein
STRING	Gorai.001G123900.1	1e-144	(Gossypium raimondii)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	1e-118	E2F transcription factor 1

Link Out ? help Back to Top
Phytozome	Kalax.0090s0054.1.p

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]