PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kalax.0047s0065.2.p
Organism
Kalanchoe marnieriana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family E2F/DP
Protein Properties Length: 354aa    MW: 39709.7 Da    PI: 9.7946
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kalax.0047s0065.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP70.91.4e-222085171
              E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                         rk+ksL+ll+++fl l++++  + v l+++a++L    v  +rRRiYDi+N+Le+++++++k+kn+++wkg
  Kalax.0047s0065.2.p 20 RKQKSLGLLCSNFLGLYNREGVQSVGLDDAANRL---GV--ERRRIYDIVNILESVGVLARKAKNQYTWKG 85
                         79*****************999************...**..****************************98 PP
2E2F_TDP77.51.2e-24153233171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                          r+eksL+lltq+f+kl+ +s+ + ++l+++ak L+ +      +++k+RR+YDi+NVL ++nliek     ++k+++rw+g
  Kalax.0047s0065.2.p 153 RREKSLGLLTQNFIKLFLCSNMKLISLDDAAKLLLGDghgstIMRTKVRRLYDIANVLISMNLIEKthhteNRKPAFRWIG 233
                          689***************************************9************************999999******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.4E-251686IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.72E-151983IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.7E-272085IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.3E-192185IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.5E-23149234IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.8E-34153233IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.34E-14155234IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023192.8E-19155233IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 354 aa     Download sequence    Send to blast
MAASSSILPD LGSTQNAYSR KQKSLGLLCS NFLGLYNREG VQSVGLDDAA NRLGVERRRI  60
YDIVNILESV GVLARKAKNQ YTWKGFGAIP RALDELKVEG LKDYHSFSDG NDHGKFSDDE  120
DERYSSQNSG SRPDKTNQVV TQNSSSSSKP DNRREKSLGL LTQNFIKLFL CSNMKLISLD  180
DAAKLLLGDG HGSTIMRTKV RRLYDIANVL ISMNLIEKTH HTENRKPAFR WIGLRERLEN  240
DSSTSLSKSN KRSFGTEITN IDFKRSRLDS ASVGKSMFGV KVQEPVQVKC ESLGYEDEKI  300
MGHDSKVKTY EFGPFAPINV SRVQTAENKP KQVNDWENLA TVYRPQYQNP VLR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A5e-40192253228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015879579.11e-146E2F transcription factor-like E2FE isoform X2
RefseqXP_024924831.11e-146E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ41e-109E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A2I4FIR81e-140A0A2I4FIR8_JUGRE; E2F transcription factor-like E2FE
STRINGXP_010111971.11e-139(Morus notabilis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.27e-95DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]