PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kalax.0006s0161.1.p

Organism

Kalanchoe marnieriana

Taxonomic ID

80907

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

LSD

Protein Properties

Length: 186aa MW: 19444.5 Da PI: 7.8648

Description

LSD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0006s0161.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-LSD1	36.4	8.4e-12	7	31	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 C++Cr lL YPrGA++V+Ca+C ++ Kalax.0006s0161.1.p 7 CSSCRSLLLYPRGATNVCCAICRAI 31 **********************986 PP
2	zf-LSD1	34.5	3.3e-11	46	70	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 CggC tlL+Y GA+s+RC++C+tV Kalax.0006s0161.1.p 46 CGGCLTLLMYACGATSIRCSCCHTV 70 ************************9 PP
3	zf-LSD1	48	2e-15	84	108	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 Cg+Crt+L+YP+GApsV+Ca+C+ V Kalax.0006s0161.1.p 84 CGNCRTTLMYPYGAPSVKCAVCQYV 108 **********************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
TIGRFAMs	TIGR01053	9.4E-12	4	34	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	1.4E-10	7	31	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	9.9E-13	43	72	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	1.5E-9	46	70	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	4.3E-13	81	111	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	3.7E-14	84	108	IPR005735	Zinc finger, LSD1-type

Sequence ? help Back to Top
Protein Sequence Length: 186 aa Download sequence Send to blast
MQSQLMCSSC RSLLLYPRGA TNVCCAICRA ITSVPPPGME MAQLICGGCL TLLMYACGAT 60 SIRCSCCHTV NLAPASNQVA HVNCGNCRTT LMYPYGAPSV KCAVCQYVTN VATSDGRVPI 120 PVSRPNGVSV SSSSTSTSTQ VMAHIQNQTV VVENPMTVDE SGKLVNYHPP YSVHLSCALS 180 LDSSA*

Functional Description ? help Back to Top
Source	Description
UniProt	Negative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269\|PubMed:10550898, ECO:0000269\|PubMed:11595797, ECO:0000269\|PubMed:11844114, ECO:0000269\|PubMed:12732715, ECO:0000269\|PubMed:15347794, ECO:0000269\|PubMed:16957775, ECO:0000269\|PubMed:18055613, ECO:0000269\|PubMed:18790826, ECO:0000269\|PubMed:20456049, ECO:0000269\|PubMed:21097903}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By methyl viologen. {ECO:0000269\|PubMed:20456049}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008225697.1	6e-87	PREDICTED: protein LSD1
Refseq	XP_022714636.1	7e-87	vacuolar protein sorting-associated protein 2 homolog 2-like
Swissprot	P94077	8e-61	LSD1_ARATH; Protein LSD1
TrEMBL	A0A2P5CRE2	5e-86	A0A2P5CRE2_PARAD; Multihem cytochrome
TrEMBL	A0A314Y6K1	1e-85	A0A314Y6K1_PRUYE; Protein LSD1
STRING	XP_008225697.1	2e-86	(Prunus mume)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G20380.7	1e-61	LSD family protein

Link Out ? help Back to Top
Phytozome	Kalax.0006s0161.1.p

Publications ? help Back to Top
Spedaletti V, et al. Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana. Biochemistry, 2008. 47(17): p. 4936-47 [PMID:18393445] Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties. Plant Cell Rep., 2016. 35(3): p. 527-39 [PMID:26754794] Czarnocka W, et al. The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator. Plant Cell Environ., 2017. 40(11): p. 2644-2662 [PMID:28555890] Bernacki MJ, et al. LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana. Physiol Plant, 2019. 165(2): p. 369-382 [PMID:30461017]