PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kaladp0068s0096.6.p

Organism

Kalanchoe laxiflora

Taxonomic ID

1670617

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

bHLH

Protein Properties

Length: 624aa MW: 71456.5 Da PI: 8.4895

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kaladp0068s0096.6.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	12.1	0.00036	528	565	15	52
HHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHH CS HLH 15 riNsafeeLrellPkaskapskKlsKaeiLekAveYIk 52 +iN+ f++Lr+++ + ++ +K+s +++L+ ++ + Kaladp0068s0096.6.p 528 QINTLFANLRRVIISYCQHEYGKVSASMTLRGCIDILL 565 7************7799**********9888765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF103657	1.74E-41	16	182	No hit	No description
Gene3D	G3DSA:1.20.1270.60	3.5E-31	16	167	IPR027267	Arfaptin homology (AH) domain/BAR domain
Pfam	PF16746	8.1E-28	18	177	No hit	No description
Gene3D	G3DSA:2.30.29.30	1.7E-25	180	367	IPR011993	PH domain-like
SuperFamily	SSF50729	6.82E-26	187	268	IPR011993	PH domain-like
SuperFamily	SSF103657	1.74E-41	232	257	No hit	No description
PROSITE profile	PS50003	18.159	234	360	IPR001849	Pleckstrin homology domain
SMART	SM00233	9.0E-21	235	362	IPR001849	Pleckstrin homology domain
Pfam	PF00169	1.2E-14	236	359	IPR001849	Pleckstrin homology domain
CDD	cd13250	1.32E-39	237	364	No hit	No description
SuperFamily	SSF50729	6.82E-26	298	359	IPR011993	PH domain-like
SuperFamily	SSF57863	8.63E-36	425	516	No hit	No description
PROSITE profile	PS50115	25.717	426	509	IPR001164	Arf GTPase activating protein
SMART	SM00105	8.9E-36	426	555	IPR001164	Arf GTPase activating protein
Pfam	PF01412	4.2E-32	428	516	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	4.0E-15	438	457	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	4.0E-15	457	474	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	4.0E-15	480	501	IPR001164	Arf GTPase activating protein

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005737	Cellular Component	cytoplasm
GO:0005096	Molecular Function	GTPase activator activity
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 624 aa Download sequence Send to blast
MTFVLMLTHN WPVSSGHIMT KFTGALREIS VYKDGLQSQV EQVLNERLFN FVNNDIHDVK 60 EARKRFDKAS SLYDQAREKF LSLRKSTRMD VAAGFEEELY RARSRFEQAR FNLIGAIYNV 120 ETKKKYEFLD AVSGAVAAHL VYFKQGYELL LQMEPLIEQI AAYTKQSQEN FTREKASLNE 180 RMQEYQRQVD QESRPSHENM VDSLRNGDCM QPSSRSSHRL IQAVMQSSSI GKVQIIRQGY 240 LSKRSSNLRG DWKRRYFVLD SRGMLYYYRK QWTRSPNAPP EYGSGILSRW RSSHYHVVHD 300 ERTVARHTVD LLTSTIKIDA DQTDLRFCFR IISPSKTYTL QAESATDQMD WIEKITGVIT 360 SLLSSQDHDT RVVNEEDFCF PTEALTPGSP FYFDSPSSDE NGVVACPGLY QKCRTIQSQS 420 QNTNNEKPIN ILRKIPGNDI CADCGAADPE WASLNLGVLI CIECSGVHRN LGVHISKVRS 480 LTLDVKVWEP SIMTLFGSLG NVYANSIWEE LLNPKSACQY DGMPISMQIN TLFANLRRVI 540 ISYCQHEYGK VSASMTLRGC IDILLLLKRI SMAFTDEYYH VSLQRNYLQT RKKLVIVSNC 600 CLVKGVVGTL YFIWLVNVRT LAW*

Sequence ? help Back to Top

Protein Sequence Length: 624 aa Download sequence Send to blast

MTFVLMLTHN WPVSSGHIMT KFTGALREIS VYKDGLQSQV EQVLNERLFN FVNNDIHDVK  60
EARKRFDKAS SLYDQAREKF LSLRKSTRMD VAAGFEEELY RARSRFEQAR FNLIGAIYNV  120
ETKKKYEFLD AVSGAVAAHL VYFKQGYELL LQMEPLIEQI AAYTKQSQEN FTREKASLNE  180
RMQEYQRQVD QESRPSHENM VDSLRNGDCM QPSSRSSHRL IQAVMQSSSI GKVQIIRQGY  240
LSKRSSNLRG DWKRRYFVLD SRGMLYYYRK QWTRSPNAPP EYGSGILSRW RSSHYHVVHD  300
ERTVARHTVD LLTSTIKIDA DQTDLRFCFR IISPSKTYTL QAESATDQMD WIEKITGVIT  360
SLLSSQDHDT RVVNEEDFCF PTEALTPGSP FYFDSPSSDE NGVVACPGLY QKCRTIQSQS  420
QNTNNEKPIN ILRKIPGNDI CADCGAADPE WASLNLGVLI CIECSGVHRN LGVHISKVRS  480
LTLDVKVWEP SIMTLFGSLG NVYANSIWEE LLNPKSACQY DGMPISMQIN TLFANLRRVI  540
ISYCQHEYGK VSASMTLRGC IDILLLLKRI SMAFTDEYYH VSLQRNYLQT RKKLVIVSNC  600
CLVKGVVGTL YFIWLVNVRT LAW*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3t9k_A	5e-21	432	509	39	114	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1
3t9k_B	5e-21	432	509	39	114	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1
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Functional Description ? help Back to Top
Source	Description
UniProt	GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Involved in the spatial control of provascular differentiation. Required for the formation of the normal pattern of continuous secondary veins. Involved in auxin signaling but not in polar auxin transport or in auxin responses. Required for PIN1 internalization in roots. {ECO:0000269\|PubMed:10887076, ECO:0000269\|PubMed:10887077, ECO:0000269\|PubMed:15743878, ECO:0000269\|PubMed:16698946}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by auxin. {ECO:0000269\|PubMed:15743878}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021814176.1	0.0	ADP-ribosylation factor GTPase-activating protein AGD3-like isoform X1
Refseq	XP_021814184.1	0.0	ADP-ribosylation factor GTPase-activating protein AGD3-like isoform X2
Swissprot	Q5W7F2	0.0	AGD3_ARATH; ADP-ribosylation factor GTPase-activating protein AGD3
TrEMBL	A0A1U7ZLB4	0.0	A0A1U7ZLB4_NELNU; ADP-ribosylation factor GTPase-activating protein AGD3
TrEMBL	A0A453L9S6	0.0	A0A453L9S6_AEGTS; Uncharacterized protein
STRING	XP_010249220.1	0.0	(Nelumbo nucifera)

Link Out ? help Back to Top
Phytozome	Kaladp0068s0096.6.p

Publications ? help Back to Top
Koizumi K,Sugiyama M,Fukuda H A series of novel mutants of Arabidopsis thaliana that are defective in the formation of continuous vascular network: calling the auxin signal flow canalization hypothesis into question. Development, 2000. 127(15): p. 3197-204 [PMID:10887076] Vernoud V,Horton AC,Yang Z,Nielsen E Analysis of the small GTPase gene superfamily of Arabidopsis. Plant Physiol., 2003. 131(3): p. 1191-208 [PMID:12644670] Sawa S,Demura T,Horiguchi G,Kubo M,Fukuda H The ATE genes are responsible for repression of transdifferentiation into xylem cells in Arabidopsis. Plant Physiol., 2005. 137(1): p. 141-8 [PMID:15618413] Sawa S, et al. DRP1A is responsible for vascular continuity synergistically working with VAN3 in Arabidopsis. Plant Physiol., 2005. 138(2): p. 819-26 [PMID:15923323] Sieburth LE, et al. SCARFACE encodes an ARF-GAP that is required for normal auxin efflux and vein patterning in Arabidopsis. Plant Cell, 2006. 18(6): p. 1396-411 [PMID:16698946] Naramoto S, et al. Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity in plants. Development, 2009. 136(9): p. 1529-38 [PMID:19363154] Carland F,Nelson T CVP2- and CVL1-mediated phosphoinositide signaling as a regulator of the ARF GAP SFC/VAN3 in establishment of foliar vein patterns. Plant J., 2009. 59(6): p. 895-907 [PMID:19473324] Naramoto S, et al. ADP-ribosylation factor machinery mediates endocytosis in plant cells. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(50): p. 21890-5 [PMID:21118984] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Prabhakaran Mariyamma N,Hou H,Carland FM,Nelson T,Schultz EA Localization of Arabidopsis FORKED1 to a RABA-positive compartment suggests a role in secretion. J. Exp. Bot., 2017. 68(13): p. 3375-3390 [PMID:28575401]