PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kaladp0067s0313.1.p
Organism
Kalanchoe laxiflora
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family HD-ZIP
Protein Properties Length: 720aa    MW: 78564.3 Da    PI: 6.2714
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kaladp0067s0313.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.64.9e-192071556
                         SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
             Homeobox  5 ttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                         ++++++q+++Le++F++++++++++r +L+++lgL  rq+k+WFqNrR+++k
  Kaladp0067s0313.1.p 20 HRHSAHQIQRLEAVFKECPHLDEKQRLQLSRELGLAPRQIKFWFQNRRTQMK 71
                         6799*********************************************998 PP
2START169.91.7e-532284491206
                          HHHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS....SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EE CS
                START   1 elaeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv...dsgealrasgvvdmvlallveellddkeqWdetla....ka 79 
                          e+a  a+++lvk+ +a+ep+W+ks+    + +n++ +l   +++      ++ea+r+sgvv m++ llv  ++d + +W et+     +a
  Kaladp0067s0313.1.p 228 EIAANAMNDLVKLLQATEPLWTKSAtdgrDTLNYENYLMLSPRAMKkpnARTEASRDSGVVAMNSLLLVDMFMDAG-KWLETFSpivsAA 316
                          57889************************999999999887776557889**************************.************* PP

                          EEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEE CS
                START  80 etlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghs 162
                          +t++v++ g      g+l lm+ elq+lsplvp R+fvf+Ry++q ++g+wvivdvS d  + +     +  +++lpSg+lie++sng s
  Kaladp0067s0313.1.p 317 KTIQVLTAGvsgslsGTLRLMYEELQVLSPLVPtREFVFLRYCQQTEKGSWVIVDVSCDFANGNRH--VLPQSRRLPSGCLIEDMSNGIS 404
                          ***************************************************************975..6666777*************** PP

                          EEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
                START 163 kvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                          kv wvehv+ ++ +  + l+  l+ksg+a+ga +w+atlqr ce+
  Kaladp0067s0313.1.p 405 KVSWVEHVEIQDDSQaDHLYGDLIKSGYAFGAERWLATLQRMCER 449
                          **********998888***************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466892.69E-19876IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.1E-20980IPR009057Homeodomain-like
PROSITE profilePS5007116.8921373IPR001356Homeobox domain
SMARTSM003891.7E-181477IPR001356Homeobox domain
CDDcd000862.07E-181573No hitNo description
PfamPF000461.4E-162071IPR001356Homeobox domain
PROSITE patternPS0002704871IPR017970Homeobox, conserved site
PROSITE profilePS5084845.725219452IPR002913START domain
SuperFamilySSF559611.01E-34220451No hitNo description
CDDcd088751.06E-105223448No hitNo description
SMARTSM002342.9E-46228449IPR002913START domain
PfamPF018528.6E-46228449IPR002913START domain
Gene3DG3DSA:3.30.530.206.2E-7280412IPR023393START-like domain
SuperFamilySSF559611.06E-17472697No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 720 aa     Download sequence    Send to blast
MEQGSAGDDS DPQKRKKRFH RHSAHQIQRL EAVFKECPHL DEKQRLQLSR ELGLAPRQIK  60
FWFQNRRTQM KGQLERADNS ILKAENDKIR CSNIALREAL KNIMCPNCGS MRIGDDPYLD  120
EQQLHLENAH LKEELDRVSS IAAKYIGRPV SQFSTTQSSH ISLIELSLGS FGGQIIPSPS  180
LGGFGSHGIT GSSLELDILS GTSSSVPPTM EIQPGSTIND MDKTLMAEIA ANAMNDLVKL  240
LQATEPLWTK SATDGRDTLN YENYLMLSPR AMKKPNARTE ASRDSGVVAM NSLLLVDMFM  300
DAGKWLETFS PIVSAAKTIQ VLTAGVSGSL SGTLRLMYEE LQVLSPLVPT REFVFLRYCQ  360
QTEKGSWVIV DVSCDFANGN RHVLPQSRRL PSGCLIEDMS NGISKVSWVE HVEIQDDSQA  420
DHLYGDLIKS GYAFGAERWL ATLQRMCERY ASLTVSGTNI HDLDGVIPTF DGKANMMKLS  480
QRMVSNFCAT VSTSTNSQQC TTLAGSNESQ VRLTVRKTAT DPGQPNGLVL CAATSIWLPV  540
SPQNAFNFLR DVSMRPQWDV LSKGGAVQEV AHISCGSHPG NYISILRASD PSQNNMVILQ  600
ECCIDSWGSL IVYSPVEIPE INMAVSGGDP SCIPLLPSGF MISPDGRSEI AHLSEASSTS  660
SSRHSSMTKS SGSLITIGFQ ILAGSSPVAK LDMESVTTVN NLIGMTIHQI KAALDCPDS*
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017973835.10.0PREDICTED: homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A2N9ELU80.0A0A2N9ELU8_FAGSY; Uncharacterized protein
STRINGXP_010099679.10.0(Morus notabilis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]