PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID kfl00203_0120
Organism
Klebsormidium flaccidum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Klebsormidiophyceae; Klebsormidiales; Klebsormidiaceae; Klebsormidium
Family C2H2
Protein Properties Length: 634aa    MW: 69967.1 Da    PI: 9.1057
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
kfl00203_0120genomeKFGPView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.60.00084357379123
                    EEETTTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                    y C++C k  +   +L+ H++++
  kfl00203_0120 357 YICEYCLKYMRKAKTLQAHLQKC 379
                    89******************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.30.30.2702.1E-32178255No hitNo description
SuperFamilySSF541603.85E-21182324IPR016197Chromo domain-like
PfamPF117174.5E-14193241IPR025995RNA binding activity-knot of a chromodomain
CDDcd000242.75E-5201237No hitNo description
Gene3DG3DSA:2.30.30.2702.1E-32318367No hitNo description
PROSITE profilePS5172672.02323624IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557292.24E-105326390IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.40.630.302.7E-68383553IPR016181Acyl-CoA N-acyltransferase
SuperFamilySSF557292.24E-105423612IPR016181Acyl-CoA N-acyltransferase
PfamPF018531.7E-80423590IPR002717Histone acetyltransferase domain, MYST-type
CDDcd043011.20E-4471522No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0016747Molecular Functiontransferase activity, transferring acyl groups other than amino-acyl groups
Sequence ? help Back to Top
Protein Sequence    Length: 634 aa     Download sequence    Send to blast
MLPAEATMPR LDETQSPLPS VHLPKQSSAR GNHAFPENGG TGRLPPSMAH ASPSLREQDA  60
APLHAKLPVL GAASVSGTGK RLANAQAPRQ HATGGFSASQ VREGGSPSAA AVQSDSRARV  120
GGVAEGRAGL QAGSASLRES QTPGKAAEQS GYRLSDSNGV RVDGNGAGPS SNGGNPGPSN  180
GMAKDYSVGD KVAALASFDQ SYHMAEVIER RKHRKGGQYD YYIHYLDQNK RLDEWLPPSK  240
VEPWTAAEFS GRGTGFGLSP LATPGTPGYS AGDKADPFTP GGSDRKLTRN LKRKYDAEHH  300
VQKSVEDLPP IDQSLEKAHE EKTKMKNIQQ IVVGKHAIDT WYYSPYPDDY ASELKLYICE  360
YCLKYMRKAK TLQAHLQKCT THRPPGEEIY HADYPIWSRL PKAEGENGRR ERSPAPIVKN  420
MVTLSMYEVD GVKNKVYCQN LCLLAKLFLD HKTLYYDVDP FLFYVLTECD EDGHHIVGYF  480
SKEKHSAEEY NLACIMTLPP YQRNGYGRFL IAFSYELSRK EGKVGTPERP LSDLGQVSFR  540
SYWMRVILEI IKEHRANISV KDISALTAIK TEDIVATLQP LNLIKYWKGQ HIISATVKLI  600
DEHLKAIDHQ PLPKIESAKL TWTPPASPAL KKPR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A1e-1173196311285Histone acetyltransferase KAT8
4dnc_B1e-1173196311285Histone acetyltransferase KAT8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024399982.10.0histone acetyltransferase of the MYST family 1-like
SwissprotQ9FLF71e-141MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLA0A1Y1I1E70.0A0A1Y1I1E7_KLENI; Histone acetyltransferase
STRINGPP1S1_162V6.20.0(Physcomitrella patens)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP389045
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  5. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  6. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]