PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

WALNUT_00003762-RA

Organism

Juglans regia

Taxonomic ID

51240

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Juglandaceae; Juglans

Family

ARR-B

Protein Properties

Length: 681aa MW: 73955 Da PI: 6.241

Description

ARR-B family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
WALNUT_00003762-RA	genome	JHU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	91.3	8.2e-29	213	266	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 kpr++W+ eLH++Fv av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl WALNUT_00003762-RA 213 KPRVVWSVELHQQFVAAVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 266 79*****************.******************************8 PP
2	Response_reg	73.8	6.4e-25	35	143	1	109
EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHH CS Response_reg 1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalea 89 vl+vdD+p+ + +l+++l+ y v+ + +e al ll+e++ +D+++ D+ mp+mdG++ll++i e +lp+i+++a +e++ + + WALNUT_00003762-RA 35 VLVVDDDPTCLVILEKMLRACLY-AVTKCNRAEIALSLLRENKngFDIVISDVHMPDMDGFKLLEHIGLEM-DLPVIMMSADDEKNVVMKG 123 89***************9999.***********999999******************6654.8************** PP HHTTESEEEESS--HHHHHH CS Response_reg 90 lkaGakdflsKpfdpeelvk 109 + Ga d+l Kp+ +e+l + WALNUT_00003762-RA 124 VTHGACDYLIKPVRIEALKN 143 **************9986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF036392	7.4E-183	11	671	IPR017053	Response regulator B-type, plant
Gene3D	G3DSA:3.40.50.2300	9.6E-41	32	172	No hit	No description
SuperFamily	SSF52172	4.27E-34	32	156	IPR011006	CheY-like superfamily
SMART	SM00448	1.8E-28	33	145	IPR001789	Signal transduction response regulator, receiver domain
PROSITE profile	PS50110	41.264	34	149	IPR001789	Signal transduction response regulator, receiver domain
Pfam	PF00072	2.6E-22	35	143	IPR001789	Signal transduction response regulator, receiver domain
CDD	cd00156	3.54E-26	36	148	No hit	No description
PROSITE profile	PS51294	11.048	210	269	IPR017930	Myb domain
SuperFamily	SSF46689	3.58E-20	210	270	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	2.5E-30	212	271	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	9.8E-25	213	266	IPR006447	Myb domain, plants
Pfam	PF00249	9.8E-8	215	265	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0000160	Biological Process	phosphorelay signal transduction system
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 681 aa Download sequence Send to blast
MNPSNGKGSI ATASSSGAWK VGDVVPDQFP AGLRVLVVDD DPTCLVILEK MLRACLYAVT 60 KCNRAEIALS LLRENKNGFD IVISDVHMPD MDGFKLLEHI GLEMDLPVIM MSADDEKNVV 120 MKGVTHGACD YLIKPVRIEA LKNIWQHVVR KRKNEWKELD QSGSLEDGDR QQKPSDEVEY 180 SSSANEGNWK SSKKRKDEEE DIEDRDDTST LKKPRVVWSV ELHQQFVAAV NQLGIDKAVP 240 KKILELMNVP GLTRENVASH LQKYRLYLRR LSGVSQHHSS LNNSFISAQE ATFGSMSSLN 300 GLDLQTLAVT GQLPAQSLAT LQAAGLGRPT AKSGIPMPLV DQRNLFSFEN PKPRFGEGQQ 360 QHLSSSKPVN LLHGIPTTME PKQLANLHQS AQPLGNMNVQ VNAHGGHSSS LLMQMGQTQS 420 RGQILNESAG SHVPRLPSSV GHPAISNGIA GGVIGINGIG DNSRGIGYNQ VRPTSSMLSF 480 PMNHTSELAS NSFPLGSTPG ISNITPKGAF QDEINSEIKG STGFGASYDI FNDLHQQKSQ 540 NWELHNVGLQ FSASQNANRL QGNLDISPSV LVRQGYSSSQ TSGQNRNVSD IGRAVFSGVE 600 STQQGNTQII GQQLNNFLVD NSVRVKAESI PDAGSQSILF PENNFGQEDL MSALLKQQQG 660 GIAPAESEFD LDGYSIDNIP V

Sequence ? help Back to Top

Protein Sequence Length: 681 aa Download sequence Send to blast

MNPSNGKGSI ATASSSGAWK VGDVVPDQFP AGLRVLVVDD DPTCLVILEK MLRACLYAVT  60
KCNRAEIALS LLRENKNGFD IVISDVHMPD MDGFKLLEHI GLEMDLPVIM MSADDEKNVV  120
MKGVTHGACD YLIKPVRIEA LKNIWQHVVR KRKNEWKELD QSGSLEDGDR QQKPSDEVEY  180
SSSANEGNWK SSKKRKDEEE DIEDRDDTST LKKPRVVWSV ELHQQFVAAV NQLGIDKAVP  240
KKILELMNVP GLTRENVASH LQKYRLYLRR LSGVSQHHSS LNNSFISAQE ATFGSMSSLN  300
GLDLQTLAVT GQLPAQSLAT LQAAGLGRPT AKSGIPMPLV DQRNLFSFEN PKPRFGEGQQ  360
QHLSSSKPVN LLHGIPTTME PKQLANLHQS AQPLGNMNVQ VNAHGGHSSS LLMQMGQTQS  420
RGQILNESAG SHVPRLPSSV GHPAISNGIA GGVIGINGIG DNSRGIGYNQ VRPTSSMLSF  480
PMNHTSELAS NSFPLGSTPG ISNITPKGAF QDEINSEIKG STGFGASYDI FNDLHQQKSQ  540
NWELHNVGLQ FSASQNANRL QGNLDISPSV LVRQGYSSSQ TSGQNRNVSD IGRAVFSGVE  600
STQQGNTQII GQQLNNFLVD NSVRVKAESI PDAGSQSILF PENNFGQEDL MSALLKQQQG  660
GIAPAESEFD LDGYSIDNIP V

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1irz_A	2e-22	212	272	4	64	ARR10-B
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Regulates SHY2 by binding to its promoter (PubMed:19039136). Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). {ECO:0000269\|PubMed:11574878, ECO:0000269\|PubMed:11691951, ECO:0000269\|PubMed:17363254, ECO:0000269\|PubMed:19039136}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by gibberellin. {ECO:0000269\|PubMed:20605455}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018825709.1	0.0	PREDICTED: two-component response regulator ARR1 isoform X1
Swissprot	Q940D0	0.0	ARR1_ARATH; Two-component response regulator ARR1
TrEMBL	A0A2I4F236	0.0	A0A2I4F236_JUGRE; Two-component response regulator
STRING	EOY06639	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3958	34	58

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G16110.1	0.0	response regulator 2

Publications ? help Back to Top
Bürkle L,Meyer S,Dortay H,Lehrach H,Heyl A In vitro recombination cloning of entire cDNA libraries in Arabidopsis thaliana and its application to the yeast two-hybrid system. Funct. Integr. Genomics, 2005. 5(3): p. 175-83 [PMID:15714319] Moubayidin L, et al. Spatial coordination between stem cell activity and cell differentiation in the root meristem. Dev. Cell, 2013. 26(4): p. 405-15 [PMID:23987513] Takahashi N, et al. Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots. Curr. Biol., 2013. 23(18): p. 1812-7 [PMID:24035544] Kurepa J,Li Y,Perry SE,Smalle JA Ectopic expression of the phosphomimic mutant version of Arabidopsis response regulator 1 promotes a constitutive cytokinin response phenotype. BMC Plant Biol., 2014. 14: p. 28 [PMID:24423196] Cortleven A, et al. A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors. Plant Physiol., 2014. 164(3): p. 1470-83 [PMID:24424319] Marín-de la Rosa N, et al. Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins. PLoS Genet., 2015. 11(7): p. e1005337 [PMID:26134422] D'Alessandro S,Golin S,Hardtke CS,Lo Schiavo F,Zottini M The co-chaperone p23 controls root development through the modulation of auxin distribution in the Arabidopsis root meristem. J. Exp. Bot., 2015. 66(16): p. 5113-22 [PMID:26163704] Jiang L, et al. Strigolactones spatially influence lateral root development through the cytokinin signaling network. J. Exp. Bot., 2016. 67(1): p. 379-89 [PMID:26519957] Moubayidin L, et al. A SCARECROW-based regulatory circuit controls Arabidopsis thaliana meristem size from the root endodermis. Planta, 2016. 243(5): p. 1159-68 [PMID:26848984] Muraro D, et al. A multi-scale model of the interplay between cell signalling and hormone transport in specifying the root meristem of Arabidopsis thaliana. J. Theor. Biol., 2016. 404: p. 182-205 [PMID:27157127] Cortleven A, et al. Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes. Plant Physiol., 2016. 172(1): p. 464-78 [PMID:27388681] Kobayashi K, et al. Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling. Plant Physiol., 2017. 173(4): p. 2340-2355 [PMID:28193764] Zhang TQ, et al. A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration. Plant Cell, 2017. 29(5): p. 1073-1087 [PMID:28389585] Kushwah S,Laxmi A The interaction between glucose and cytokinin signaling in controlling Arabidopsis thaliana seedling root growth and development. Plant Signal Behav, 2017. 12(5): p. e1312241 [PMID:28467152] Meng WJ, et al. Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL. Plant Cell, 2017. 29(6): p. 1357-1372 [PMID:28576846] Kobayashi K,Iwase A Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal. Plant Signal Behav, 2017. 12(6): p. e1338999 [PMID:28594268] Liu B,De Storme N,Geelen D Cold interferes with male meiotic cytokinesis in Arabidopsis thaliana independently of the AHK2/3-AHP2/3/5 cytokinin signaling module. Cell Biol. Int., 2017. 41(8): p. 879-889 [PMID:28618065] Zhang F,May A,Irish VF Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL. Trends Plant Sci., 2017. 22(10): p. 815-817 [PMID:28886911] Yan Z, et al. Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1. Plant Physiol., 2017. 175(3): p. 1438-1454 [PMID:28931628] Rong XF, et al. Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis. Plant Cell Physiol., 2018. 59(4): p. 756-764 [PMID:29186581] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938] Waldie T,Leyser O Cytokinin Targets Auxin Transport to Promote Shoot Branching. Plant Physiol., 2018. 177(2): p. 803-818 [PMID:29717021]