PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID WALNUT_00001229-RA
Organism
Juglans regia
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Juglandaceae; Juglans
Family HD-ZIP
Protein Properties Length: 596aa    MW: 66214.8 Da    PI: 7.633
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
WALNUT_00001229-RAgenomeJHUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox421.6e-133411856
                        HHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
            Homeobox 18 lFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                        +F+  ++p++++r++L+++l+L+ +q+k+WFqN+R++ k
  WALNUT_00001229-RA  3 FFKDYPHPDEKQRRQLSRRLELEPKQIKFWFQNKRTQTK 41
                        59999******************************9987 PP
2START22.81.8e-08155259389
                         HHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS............SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....E CS
               START   3 aeeaaqelvkkalaeepgWvkssesengdevlqkfeeskv...........dsgealrasgvvdmvlallveellddkeqWdetla....k 78 
                         a  a++el+++   +ep+W ks   ++g +vl  ++ +k             ++e +++s +v+   + lve +ld+  +W   ++    k
  WALNUT_00001229-RA 155 AAGAMDELIRLLRINEPLWIKSL--DDGRYVLHHESYGKLfptinhfrnpsARVESSKDSDIVTVSGMHLVEMILDSE-KWVDLFPtivtK 242
                         6679*******************..9999999999888878999999*******************************.99999988889* PP

                         EEEEEEECTT......E CS
               START  79 aetlevissg......g 89 
                         a+t++v+++g      g
  WALNUT_00001229-RA 243 AKTIQVLETGtlgnrsG 259
                         *********96555555 PP
3START43.21.1e-14272332147206
                         ESSEEEEEEEECTCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
               START 147 llpSgiliepksnghskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                         ++pSg++i++++ng skvtwvehv+++++   h l+r l+  +la ga +w  tl+r ce+
  WALNUT_00001229-RA 272 RFPSGCMIQEMPNGCSKVTWVEHVEVDDKNQtHRLYRDLICGSLAYGAERWIVTLKRMCER 332
                         79************************988766***************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007113.637143IPR001356Homeobox domain
SMARTSM003890.0095247IPR001356Homeobox domain
PfamPF000466.4E-11341IPR001356Homeobox domain
SuperFamilySSF466891.28E-10352IPR009057Homeodomain-like
CDDcd000869.01E-11344No hitNo description
Gene3DG3DSA:1.10.10.601.2E-11349IPR009057Homeodomain-like
PROSITE patternPS0002701841IPR017970Homeobox, conserved site
PROSITE profilePS5084815.194144253IPR002913START domain
SuperFamilySSF559619.48E-14145334No hitNo description
CDDcd088752.16E-74148331No hitNo description
PfamPF018527.6E-10271332IPR002913START domain
PROSITE profilePS5084816.713272335IPR002913START domain
SuperFamilySSF559612.33E-12353560No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 596 aa     Download sequence    Send to blast
MVFFKDYPHP DEKQRRQLSR RLELEPKQIK FWFQNKRTQT KAQHERADNS VLRSENDRIQ  60
CENVAIREAL KNHEKVSNLL AKYIGKPISQ FESLIPMVPR SSLGFSPGTS MNQRLGNPAL  120
DLDLSYSPAS SNNTAFLYQL KGIPNMEKAL MLETAAGAMD ELIRLLRINE PLWIKSLDDG  180
RYVLHHESYG KLFPTINHFR NPSARVESSK DSDIVTVSGM HLVEMILDSE KWVDLFPTIV  240
TKAKTIQVLE TGTLGNRSGS LQLNIPPSCS WRFPSGCMIQ EMPNGCSKVT WVEHVEVDDK  300
NQTHRLYRDL ICGSLAYGAE RWIVTLKRMC ERFSYSNGEI TPSHELGGEF SSPEGRRSVM  360
KLSHRMVKNF CGILSMSGKL DFPHQLSELY NSGVRVSVHK SREPGQPGGI IVSAATSLWL  420
PLPPQNVFDF IREEKMRVQW DVLSDGKPVH EISRISIGAH LGNSISIIQP FIPAESNMLM  480
LQESWIDSLG SLVVYAPIDM PSISMAMSGE DPSNIPILPS GFVISSDGHP ETGSAGASTS  540
KNAGMSGGSL LTVAFQILVS SPSSKQLNME SVATVNTLIS STVQRIKAAL NCSGLD
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018816719.10.0PREDICTED: homeobox-leucine zipper protein ROC8
SwissprotQ9FX311e-178HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A2I4EBE30.0A0A2I4EBE3_JUGRE; homeobox-leucine zipper protein ROC8
STRINGEMJ161970.0(Prunus persica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF10263398
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.11e-174homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]