PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Jcr4S03490.40
Common NameJCGZ_10856, LOC105636397
Organism
Jatropha curcas
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae; Jatropha
Family E2F/DP
Protein Properties Length: 421aa    MW: 46888.3 Da    PI: 4.3693
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Jcr4S03490.40genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.81.6e-2798163171
        E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                    r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Jcr4S03490.40  98 RYDSSLGLLTKKFINLIKHAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 163
                    6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.5E-2995165IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.2E-3598163IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.63E-1798161IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.4E-24100163IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.49E-49174281No hitNo description
SuperFamilySSF1440745.23E-34176281No hitNo description
PfamPF164213.2E-34179279IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 421 aa     Download sequence    Send to blast
MHMQTRTFEV DAHPLKRKSD ATEHEAESSE WNTGPGFTEV VTSPLQTPVS GKGGKVPKTS  60
RLSKSSKSGP QNAASSLVWS IILVGSPANN LTPTGPCRYD SSLGLLTKKF INLIKHAEDG  120
ILDLNKAADT LEVQKRRIYD ITNVLEGIGL IEKKLKNRIQ WKGLDVSRPG EADDNVASLQ  180
AEVENLNLQE RRLDEQIREM QERLRDLSED ENNQKWLFVT EEDIKSLPSL QNETLIAIKA  240
PHGTTLEVPD PDEQAVDYPQ RRYRIVLRST MGPIDVYLVS QFEEKFEEIQ GVEPPPNYPS  300
SSGFNENMDT TMIPGESRGK EIEMQGQDSN RMCSDLTTSQ DFVSGLMKIV PSEVDSDADY  360
WLLSDADVSI TDMWRTEPGV EWNEFGTLQD DYGMANVSTP QPQTPPLNPA EVPPNANTTA  420
G
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-2693164274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00661PBMTransfer from Pp3c1_6880Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY1795061e-171AY179506.1 Populus alba E2F mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012075044.10.0transcription factor E2FB isoform X1
SwissprotQ9FV711e-151E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A067KKC20.0A0A067KKC2_JATCU; Uncharacterized protein
STRINGcassava4.1_007247m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.21e-154E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Zhang L, et al.
    Global analysis of gene expression profiles in physic nut (Jatropha curcas L.) seedlings exposed to salt stress.
    PLoS ONE, 2014. 9(5): p. e97878
    [PMID:24837971]
  4. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]