PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Itr_sc001669.1_g00011.1

Organism

Ipomoea trifida

Taxonomic ID

35884

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea

Family

E2F/DP

Protein Properties

Length: 343aa MW: 38421.1 Da PI: 5.7367

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Itr_sc001669.1_g00011.1	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	61.1	1.6e-19	84	136	1	58
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnl 58 r+++sL+llt+kf++l++++e+g+++ln a+ L +v ++RRiYDi+NVLe++++ Itr_sc001669.1_g00011.1 84 RYDNSLGLLTKKFIQLIQEAEDGTLDLNRSADIL---EV--QKRRIYDITNVLEGVGI 136 689*****************************...99..************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	4.0E-20	82	136	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	1.17E-11	84	136	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	4.5E-19	84	187	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	4.1E-17	86	136	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	1.92E-30	152	259	No hit	No description
Pfam	PF16421	2.5E-22	160	257	IPR032198	E2F transcription factor, CC-MB domain
SuperFamily	SSF144074	8.63E-24	160	259	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 343 aa Download sequence Send to blast
MTRLLTSGRP AGYRTGPCTG NDDRLVGSRY QVQKTAETAN NSLLQQATFA AECRKARATK 60 RAKYGTQGIN SDPLDSLNVA GSCRYDNSLG LLTKKFIQLI QEAEDGTLDL NRSADILEVQ 120 KRRIYDITNV LEGVGIDLHR GFETTESREL QDQVYRLKVA EVEHLYTEDQ QLDYCIRKKL 180 EQLRALESDL NCQKNLFLTE DDIMSLPRFK DQTIIAVKAP YASSVKVPDP SEDGVFPEKH 240 YRLIVRSTTG PIDLYLLSKK DGQHEDVNVK HAISSDSLTG NGSRDNKMDI TMSSVSSDTS 300 TLNAKKLSQI QKIMPSHASI DDDYWLCSDK VVSATELWGR DDS

Sequence ? help Back to Top

Protein Sequence Length: 343 aa Download sequence Send to blast

MTRLLTSGRP AGYRTGPCTG NDDRLVGSRY QVQKTAETAN NSLLQQATFA AECRKARATK  60
RAKYGTQGIN SDPLDSLNVA GSCRYDNSLG LLTKKFIQLI QEAEDGTLDL NRSADILEVQ  120
KRRIYDITNV LEGVGIDLHR GFETTESREL QDQVYRLKVA EVEHLYTEDQ QLDYCIRKKL  180
EQLRALESDL NCQKNLFLTE DDIMSLPRFK DQTIIAVKAP YASSVKVPDP SEDGVFPEKH  240
YRLIVRSTTG PIDLYLLSKK DGQHEDVNVK HAISSDSLTG NGSRDNKMDI TMSSVSSDTS  300
TLNAKKLSQI QKIMPSHASI DDDYWLCSDK VVSATELWGR DDS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	9e-17	83	136	6	60	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
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Functional Description ? help Back to Top
Source	Description
UniProt	Involved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12468727, ECO:0000269\|PubMed:16920782, ECO:0000269\|PubMed:19662336}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by light. {ECO:0000269\|PubMed:12468727, ECO:0000269\|PubMed:18424613}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019156548.1	0.0	PREDICTED: transcription factor E2FC-like
Swissprot	Q9FV70	4e-69	E2FC_ARATH; Transcription factor E2FC
TrEMBL	A0A328E6R0	1e-156	A0A328E6R0_9ASTE; Uncharacterized protein
STRING	XP_009783024.1	1e-118	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA12625	20	22

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G47870.1	2e-71	E2F/DP family protein

Publications ? help Back to Top
Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Huntley R, et al. The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins. Plant Mol. Biol., 1998. 37(1): p. 155-69 [PMID:9620273]