PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Itr_sc001585.1_g00006.1

Organism

Ipomoea trifida

Taxonomic ID

35884

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea

Family

E2F/DP

Protein Properties

Length: 444aa MW: 49528.4 Da PI: 4.8055

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Itr_sc001585.1_g00006.1	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	86.1	2.6e-27	122	187	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Itr_sc001585.1_g00006.1 122 RYDSSLGLLTKKFINLIRHAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 187 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	5.4E-29	120	189	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	6.26E-17	122	185	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.0E-34	122	187	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	2.2E-24	124	187	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	9.07E-45	197	313	No hit	No description
SuperFamily	SSF144074	3.66E-29	199	313	No hit	No description
Pfam	PF16421	1.2E-31	202	311	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 444 aa Download sequence Send to blast
MQQDLKRQQL PFTVVKPPSG DFRRFSADHP RHSPPQQPDD IIVNTPPLKW KSDMVSHSQV 60 PSDQDPSFGY AVNSPMQTPV SGKARKAQRV PRTSKSRRYV SQNAVDDGSP SGNNVTPVGS 120 CRYDSSLGLL TKKFINLIRH AEDGILDLNK AADTLEVQKR RIYDITNVLE GIGLIEKKLK 180 NRIQWKGLDV SRTSDFDGVS NLQAEVEKLM LKERRIDEQI REMQDRLRDL SEDENNKGYC 240 VLGCSSSLWL FVTEEDIKGL PCFQNETLLA IKAPHGTTLE VPDPDEAVDY PQRRYRIILR 300 STMGPIDVYL VSQFEKKLEE INAVDVAPSI HSTSGANENA TAMVETEESR GNEVLQEKET 360 ERVSSNVGTS QDFTSGIMKI VPDVDNEADY WLLSDADVSI TDMWTTELHE DYTTANISTP 420 RAQTPPVAAE TPSAANTAVS LPAV

Sequence ? help Back to Top

Protein Sequence Length: 444 aa Download sequence Send to blast

MQQDLKRQQL PFTVVKPPSG DFRRFSADHP RHSPPQQPDD IIVNTPPLKW KSDMVSHSQV  60
PSDQDPSFGY AVNSPMQTPV SGKARKAQRV PRTSKSRRYV SQNAVDDGSP SGNNVTPVGS  120
CRYDSSLGLL TKKFINLIRH AEDGILDLNK AADTLEVQKR RIYDITNVLE GIGLIEKKLK  180
NRIQWKGLDV SRTSDFDGVS NLQAEVEKLM LKERRIDEQI REMQDRLRDL SEDENNKGYC  240
VLGCSSSLWL FVTEEDIKGL PCFQNETLLA IKAPHGTTLE VPDPDEAVDY PQRRYRIILR  300
STMGPIDVYL VSQFEKKLEE INAVDVAPSI HSTSGANENA TAMVETEESR GNEVLQEKET  360
ERVSSNVGTS QDFTSGIMKI VPDVDNEADY WLLSDADVSI TDMWTTELHE DYTTANISTP  420
RAQTPPVAAE TPSAANTAVS LPAV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	3e-25	122	188	7	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019163334.1	0.0	PREDICTED: transcription factor E2FB-like isoform X1
Swissprot	Q9FV71	1e-131	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A2G3BAT2	0.0	A0A2G3BAT2_CAPCH; Transcription factor E2FB
STRING	Solyc11g068800.1.1	0.0	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	1e-133	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]