PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Itr_sc001095.1_g00009.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea
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Family | E2F/DP | ||||||||
Protein Properties | Length: 382aa MW: 43173.8 Da PI: 9.3682 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 76 | 3.8e-24 | 17 | 82 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++fl+l++++ +++ l+++ak+L v +rRRiYDi+NVLe+++++++k+kn+++wkg Itr_sc001095.1_g00009.1 17 RKQKSLGLLCSNFLSLYSREGVETIGLDDAAKQL---GV--ERRRIYDIVNVLESVGVLSRKAKNRYTWKG 82 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 72.8 | 3.8e-23 | 145 | 225 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL+lltq+f+kl+ +++ ++++l+e+ak L+ + ++k+RR+YDi+NVL++++ iek ++k+++rw g Itr_sc001095.1_g00009.1 145 RREKSLGLLTQNFIKLFLCTNVDMLCLDEAAKILLGDgrppsINRTKVRRLYDIANVLSSMKFIEKthhpeTRKPAFRWLG 225 689**************************************97779*********************99999*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 9.0E-27 | 15 | 84 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 6.12E-16 | 17 | 80 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 4.7E-29 | 17 | 82 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.7E-21 | 18 | 82 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 1.3E-22 | 141 | 227 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 7.0E-32 | 145 | 225 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 7.48E-11 | 147 | 226 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 1.3E-17 | 147 | 225 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 382 aa Download sequence Send to blast |
MALVSSASKD SGSVYCRKQK SLGLLCSNFL SLYSREGVET IGLDDAAKQL GVERRRIYDI 60 VNVLESVGVL SRKAKNRYTW KGFEAIPRAF QELKEEGLKE SFSAYSGDVS VQVSDDEEDD 120 RHSNPNVSSQ NEKSDSISAP KPDNRREKSL GLLTQNFIKL FLCTNVDMLC LDEAAKILLG 180 DGRPPSINRT KVRRLYDIAN VLSSMKFIEK THHPETRKPA FRWLGLKGKS ENQAANASED 240 NLGCNQSRKR VFGTELTNTT TKRCKLDKSK DAFGESMKSK LAAQVKCENL ENEFDRPKQD 300 LGSRTNRKSY QFGPFAPVTV PKFEASESGE RTKVIRELES LASTYHPQYH NQALRDLFSH 360 YMEAWKSWYL EIAGKKPIQM LS |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 3e-36 | 17 | 217 | 4 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_019197186.1 | 0.0 | PREDICTED: E2F transcription factor-like E2FE isoform X2 | ||||
Swissprot | Q8LSZ4 | 1e-117 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | A0A0V0I592 | 0.0 | A0A0V0I592_SOLCH; Putative E2F transcription factor-like E2FE-like | ||||
STRING | XP_009607525.1 | 0.0 | (Nicotiana tomentosiformis) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA2522 | 24 | 57 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 1e-119 | DP-E2F-like 1 |
Publications ? help Back to Top | |||
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