PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Itr_sc000228.1_g00010.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea
Family MYB_related
Protein Properties Length: 194aa    MW: 22163.9 Da    PI: 8.9537
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Itr_sc000228.1_g00010.1genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding54.72.3e-171269147
                             TSSS-HHHHHHHHHHHHHTTTT............-HHHHHHHHTTTS-HHHHHHHHHHH CS
          Myb_DNA-binding  1 rgrWTteEdellvdavkqlGgg............tWktIartmgkgRtlkqcksrwqky 47
                             +g+W++eEd ll ++++++G g            +W++Ia +++ gRt++++k++w+++
  Itr_sc000228.1_g00010.1 12 KGAWSEEEDNLLRKCIQKYGEGkwhlipfraglnRWSLIAGRIP-GRTANDVKNYWNTH 69
                             79******************************************.************97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129419.361774IPR017930Myb domain
Gene3DG3DSA:1.10.10.602.5E-19874IPR009057Homeodomain-like
SuperFamilySSF466892.72E-13966IPR009057Homeodomain-like
SMARTSM007171.9E-151172IPR001005SANT/Myb domain
PfamPF002498.9E-161269IPR001005SANT/Myb domain
CDDcd001679.20E-131470No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 194 aa     Download sequence    Send to blast
MANSCAWSGV RKGAWSEEED NLLRKCIQKY GEGKWHLIPF RAGLNRWSLI AGRIPGRTAN  60
DVKNYWNTHI QKKVFAMAAA SSDNWKGKAR ENRENTVVRP RPRRLSRTPL TGKATAVTYD  120
AQIQGHKIAT SELVMENLQQ NNTITSELET TTSNDRLQWW EDFLFDNEGN TCMNQGQVCW  180
ANFPTDMDLS QLIS
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator, when associated with BHLH12/MYC1, EGL3, or GL3. Promotes the synthesis of. phenylpropanoid-derived compounds such as anthocyanins and proanthocyanidin, probably together with GL3 and BHLH2. Regulates the expression of CHS, DFRA, LDOX, and BAN. {ECO:0000269|PubMed:11148285, ECO:0000269|PubMed:12917293, ECO:0000269|PubMed:15361138, ECO:0000269|PubMed:15807784, ECO:0000269|PubMed:16299184, ECO:0000269|PubMed:17147621}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By jasmonic acid (JA), NaCl, sucrose, UV light, nitrogen deficiency and drought. {ECO:0000269|PubMed:16463103, ECO:0000269|PubMed:17053893, ECO:0000269|PubMed:9839469}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB2342128e-58AB234212.1 Ipomoea nil InMYB3 gene for R2R3-MYB transcriptional regulator, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019182605.19e-91PREDICTED: transcription factor MYB75-like
SwissprotQ9FE252e-27MYB75_ARATH; Transcription factor MYB75
TrEMBLQ1HAY11e-106Q1HAY1_IPONI; R2R3-MYB transcriptional regulator
STRINGXP_009605381.11e-38(Nicotiana tomentosiformis)
STRINGXP_009627993.11e-38(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA12242154
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G66380.13e-29myb domain protein 114
Publications ? help Back to Top
  1. Zhang Y, et al.
    Pathway engineering for phenolic acid accumulations in Salvia miltiorrhiza by combinational genetic manipulation.
    Metab. Eng., 2014. 21: p. 71-80
    [PMID:24269612]
  2. Schnaubelt D, et al.
    Low glutathione regulates gene expression and the redox potentials of the nucleus and cytosol in Arabidopsis thaliana.
    Plant Cell Environ., 2015. 38(2): p. 266-79
    [PMID:24329757]
  3. Liu W, et al.
    Synthetic TAL effectors for targeted enhancement of transgene expression in plants.
    Plant Biotechnol. J., 2014. 12(4): p. 436-46
    [PMID:24373379]
  4. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  5. Ilk N,Ding J,Ihnatowicz A,Koornneef M,Reymond M
    Natural variation for anthocyanin accumulation under high-light and low-temperature stress is attributable to the ENHANCER OF AG-4 2 (HUA2) locus in combination with PRODUCTION OF ANTHOCYANIN PIGMENT1 (PAP1) and PAP2.
    New Phytol., 2015. 206(1): p. 422-35
    [PMID:25425527]
  6. Li T, et al.
    Jasmonic acid enhancement of anthocyanin accumulation is dependent on phytochrome A signaling pathway under far-red light in Arabidopsis.
    Biochem. Biophys. Res. Commun., 2014. 454(1): p. 78-83
    [PMID:25450360]
  7. Shin DH, et al.
    Identification of genes that may regulate the expression of the transcription factor production of anthocyanin pigment 1 (PAP1)/MYB75 involved in Arabidopsis anthocyanin biosynthesis.
    Plant Cell Rep., 2015. 34(5): p. 805-15
    [PMID:25604992]
  8. Tian J, et al.
    McMYB10 regulates coloration via activating McF3'H and later structural genes in ever-red leaf crabapple.
    Plant Biotechnol. J., 2015. 13(7): p. 948-61
    [PMID:25641214]
  9. Wang L,ZengJ HQ,Song J,Feng SJ,Yang ZM
    miRNA778 and SUVH6 are involved in phosphate homeostasis in Arabidopsis.
    Plant Sci., 2015. 238: p. 273-85
    [PMID:26259194]
  10. Lotkowska ME, et al.
    The Arabidopsis Transcription Factor MYB112 Promotes Anthocyanin Formation during Salinity and under High Light Stress.
    Plant Physiol., 2015. 169(3): p. 1862-80
    [PMID:26378103]
  11. Boter M, et al.
    FILAMENTOUS FLOWER Is a Direct Target of JAZ3 and Modulates Responses to Jasmonate.
    Plant Cell, 2015. 27(11): p. 3160-74
    [PMID:26530088]
  12. He X,Li Y,Lawson D,Xie DY
    Metabolic engineering of anthocyanins in dark tobacco varieties.
    Physiol Plant, 2017. 159(1): p. 2-12
    [PMID:27229540]
  13. Broeckling BE,Watson RA,Steinwand B,Bush DR
    Intronic Sequence Regulates Sugar-Dependent Expression of Arabidopsis thaliana Production of Anthocyanin Pigment-1/MYB75.
    PLoS ONE, 2016. 11(6): p. e0156673
    [PMID:27248141]
  14. Li Y, et al.
    Two IIIf Clade-bHLHs from Freesia hybrida Play Divergent Roles in Flavonoid Biosynthesis and Trichome Formation when Ectopically Expressed in Arabidopsis.
    Sci Rep, 2016. 6: p. 30514
    [PMID:27465838]
  15. Lee WJ, et al.
    Drastic anthocyanin increase in response to PAP1 overexpression in fls1 knockout mutant confers enhanced osmotic stress tolerance in Arabidopsis thaliana.
    Plant Cell Rep., 2016. 35(11): p. 2369-2379
    [PMID:27562381]
  16. Khare D, et al.
    Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana.
    New Phytol., 2017. 213(3): p. 1257-1273
    [PMID:27768815]
  17. Li S, et al.
    MYB75 Phosphorylation by MPK4 Is Required for Light-Induced Anthocyanin Accumulation in Arabidopsis.
    Plant Cell, 2016. 28(11): p. 2866-2883
    [PMID:27811015]
  18. Sawano H, et al.
    Double-stranded RNA-binding protein DRB3 negatively regulates anthocyanin biosynthesis by modulating PAP1 expression in Arabidopsis thaliana.
    J. Plant Res., 2017. 130(1): p. 45-55
    [PMID:27995376]
  19. Zou B, et al.
    Calmodulin-binding protein CBP60g functions as a negative regulator in Arabidopsis anthocyanin accumulation.
    PLoS ONE, 2017. 12(3): p. e0173129
    [PMID:28253311]
  20. Zhang Y, et al.
    GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation.
    Plant Cell Rep., 2017. 36(4): p. 557-569
    [PMID:28275852]
  21. Mondal SK,Roy S
    Genome-wide sequential, evolutionary, organizational and expression analyses of phenylpropanoid biosynthesis associated MYB domain transcription factors in Arabidopsis.
    J. Biomol. Struct. Dyn., 2018. 36(6): p. 1577-1601
    [PMID:28490275]
  22. Xu Z,Mahmood K,Rothstein SJ
    ROS Induces Anthocyanin Production Via Late Biosynthetic Genes and Anthocyanin Deficiency Confers the Hypersensitivity to ROS-Generating Stresses in Arabidopsis.
    Plant Cell Physiol., 2017. 58(8): p. 1364-1377
    [PMID:28586465]
  23. Park JJ,Dempewolf E,Zhang W,Wang ZY
    RNA-guided transcriptional activation via CRISPR/dCas9 mimics overexpression phenotypes in Arabidopsis.
    PLoS ONE, 2017. 12(6): p. e0179410
    [PMID:28622347]
  24. Lowder LG,Paul JW,Qi Y
    Multiplexed Transcriptional Activation or Repression in Plants Using CRISPR-dCas9-Based Systems.
    Methods Mol. Biol., 2017. 1629: p. 167-184
    [PMID:28623586]
  25. Kataya ARA, et al.
    PLATINUM SENSITIVE 2 LIKE impacts growth, root morphology, seed set, and stress responses.
    PLoS ONE, 2017. 12(7): p. e0180478
    [PMID:28678890]
  26. Duan S, et al.
    Functional characterization of a heterologously expressed Brassica napus WRKY41-1 transcription factor in regulating anthocyanin biosynthesis in Arabidopsis thaliana.
    Plant Sci., 2018. 268: p. 47-53
    [PMID:29362083]