PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | MLOC_70470.4 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum
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Family | E2F/DP | ||||||||
Protein Properties | Length: 175aa MW: 19962.6 Da PI: 4.4966 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 79.4 | 3.2e-25 | 1 | 60 | 7 | 71 |
E2F_TDP 7 rlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 +llt+kf++ll+++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liek+ kn+irwkg MLOC_70470.4 1 GLLTKKFINLLKQAEDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 60 589*************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.1E-25 | 1 | 62 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 1.3E-22 | 1 | 60 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SMART | SM01372 | 4.0E-27 | 1 | 60 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 9.75E-17 | 2 | 61 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
CDD | cd14660 | 1.42E-45 | 70 | 174 | No hit | No description |
SuperFamily | SSF144074 | 2.88E-33 | 73 | 174 | No hit | No description |
Pfam | PF16421 | 3.6E-33 | 75 | 174 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 175 aa Download sequence Send to blast |
GLLTKKFINL LKQAEDGILD LNNAAETLEV QKRRIYDITN VLEGIGLIEK TLKNRIRWKG 60 LDDSGVELDN GLSGLQTEVE NLNLQEQALD ERISDMREKL RGLTEDENSQ RWLYVTEDDI 120 KGLPCFQNET LIAIKAPHGT TLEVPDPDEA GDYLQRRYRI VLRSTLGPID VYLVR |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 1e-22 | 1 | 61 | 13 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | MLOC_70470.4 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AK363462 | 0.0 | AK363462.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv2015K22. | |||
GenBank | AK366396 | 0.0 | AK366396.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv2042K03. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_020183251.1 | 1e-120 | transcription factor E2FA-like isoform X1 | ||||
Refseq | XP_020183252.1 | 1e-120 | transcription factor E2FA-like isoform X2 | ||||
Swissprot | Q9FV71 | 4e-85 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | A0A453NYC0 | 1e-121 | A0A453NYC0_AEGTS; Uncharacterized protein | ||||
STRING | MLOC_70470.2 | 1e-120 | (Hordeum vulgare) | ||||
STRING | Traes_6AS_9596E4B58.1 | 1e-120 | (Triticum aestivum) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G22220.2 | 2e-87 | E2F transcription factor 1 |
Publications ? help Back to Top | |||
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