PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | MLOC_70470.3 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum
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Family | E2F/DP | ||||||||
Protein Properties | Length: 340aa MW: 38293.9 Da PI: 4.4424 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 78.7 | 5.4e-25 | 44 | 103 | 7 | 71 |
E2F_TDP 7 rlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 +llt+kf++ll+++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liek+ kn+irwkg MLOC_70470.3 44 GLLTKKFINLLKQAEDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 103 79**************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
SMART | SM01372 | 6.4E-28 | 42 | 103 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.82E-16 | 43 | 104 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 2.4E-22 | 44 | 103 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 1.8E-25 | 44 | 105 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF144074 | 4.45E-29 | 119 | 210 | No hit | No description |
CDD | cd14660 | 1.61E-42 | 119 | 210 | No hit | No description |
Pfam | PF16421 | 2.5E-29 | 119 | 208 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 340 aa Download sequence Send to blast |
MAISLTPHSY VPCRLGSFRI WLHLNLCSML LCTATYIYPD PSSGLLTKKF INLLKQAEDG 60 ILDLNNAAET LEVQKRRIYD ITNVLEGIGL IEKTLKNRIR WKGLDDSGVE LDNGLSGLQE 120 QALDERISDM REKLRGLTED ENSQRWLYVT EDDIKGLPCF QNETLIAIKA PHGTTLEVPD 180 PDEAGDYLQR RYRIVLRSTL GPIDVYLVSQ FDDGFENLGG AATPPRHTNV PEHGPCEDLH 240 ATYATQSSKS INVEYNIQHR QNTPQDPTSN DYGGMTRIIP SDVNTDADYW LLTEGDVSIT 300 DMWETAPEVQ WDTAVFLPED VSSPHAHHSP RMEVPSMDQP |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 1e-21 | 40 | 104 | 9 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | MLOC_70470.3 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AK366396 | 0.0 | AK366396.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv2042K03. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_020183251.1 | 0.0 | transcription factor E2FA-like isoform X1 | ||||
Swissprot | Q9FNY0 | 6e-96 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A3B6NQ24 | 0.0 | A0A3B6NQ24_WHEAT; Uncharacterized protein | ||||
TrEMBL | A0A3B6QEE5 | 0.0 | A0A3B6QEE5_WHEAT; Uncharacterized protein | ||||
TrEMBL | A0A446VDY7 | 0.0 | A0A446VDY7_TRITD; Uncharacterized protein | ||||
STRING | MLOC_70470.2 | 0.0 | (Hordeum vulgare) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-98 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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