PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | MLOC_67050.2 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum
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Family | E2F/DP | ||||||||
Protein Properties | Length: 386aa MW: 43314.7 Da PI: 7.6277 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 72.3 | 5.3e-23 | 17 | 82 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++f++l+ + + ++v l+++a++L v +rRRiYDi+NVLe+++++ +++kn+++w+g MLOC_67050.2 17 RKQKSLGLLCSNFVALYDRDDVETVGLDDAARRL---GV--ERRRIYDIVNVLESVGILVRRAKNRYTWIG 82 79****************9999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 78.9 | 4.7e-25 | 161 | 241 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 rkeksL+lltq+f+kl+ + e ++v+l+e+a+ L+ e ++++k+RR+YDi+NVL++lnliek ++k+++rw g MLOC_67050.2 161 RKEKSLGLLTQNFVKLFLTMEVETVSLDEAARLLLGErhaesNMRTKVRRLYDIANVLSSLNLIEKtqqvdSRKPAFRWLG 241 79****************************************************************9999999******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 7.0E-26 | 13 | 83 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 9.74E-17 | 16 | 81 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 8.6E-29 | 17 | 82 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 6.5E-21 | 18 | 82 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 1.8E-23 | 158 | 242 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.4E-32 | 161 | 241 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.5E-20 | 162 | 241 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 9.52E-13 | 163 | 241 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 386 aa Download sequence Send to blast |
SGSGAAARAC RHHSYSRKQK SLGLLCSNFV ALYDRDDVET VGLDDAARRL GVERRRIYDI 60 VNVLESVGIL VRRAKNRYTW IGFEGVPAAL KELKERTLRE MSGLAPPPEE PSATNVSDDE 120 DEDDKLGDAD GDADSEKLSQ SLDNASDKPD APMCPLRSDH RKEKSLGLLT QNFVKLFLTM 180 EVETVSLDEA ARLLLGERHA ESNMRTKVRR LYDIANVLSS LNLIEKTQQV DSRKPAFRWL 240 GQAKRKEGAA VTVALPPNRK IMSSKRAFGT DITNIDNKRG KLVLETENKP KLMQAGSSML 300 KTFESQLGQG KSSGFVYGPF HPAGARKQEV DDQTVRENET KNIQDWESLA VSFRPQYQNH 360 ALNDLFGHYV EAWRSWYLDL TRESTS |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 1e-37 | 16 | 233 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | MLOC_67050.2 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AK375358 | 0.0 | AK375358.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv3092B12. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_020187544.1 | 0.0 | E2F transcription factor-like E2FE isoform X2 | ||||
Swissprot | Q8LSZ4 | 1e-105 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | A0A287W6S3 | 0.0 | A0A287W6S3_HORVV; Uncharacterized protein | ||||
STRING | MLOC_67050.1 | 0.0 | (Hordeum vulgare) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 1e-107 | DP-E2F-like 1 |
Publications ? help Back to Top | |||
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