PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MLOC_67050.1
Organism
Hordeum vulgare
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum
Family E2F/DP
Protein Properties Length: 387aa    MW: 43413.8 Da    PI: 7.6277
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MLOC_67050.1genomeIBSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.35.3e-231782171
       E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                  rk+ksL+ll+++f++l+ + + ++v l+++a++L    v  +rRRiYDi+NVLe+++++ +++kn+++w+g
  MLOC_67050.1 17 RKQKSLGLLCSNFVALYDRDDVETVGLDDAARRL---GV--ERRRIYDIVNVLESVGILVRRAKNRYTWIG 82
                  79****************9999************...**..****************************98 PP
2E2F_TDP78.94.7e-25162242171
       E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                   rkeksL+lltq+f+kl+ + e ++v+l+e+a+ L+ e     ++++k+RR+YDi+NVL++lnliek     ++k+++rw g
  MLOC_67050.1 162 RKEKSLGLLTQNFVKLFLTMEVETVSLDEAARLLLGErhaesNMRTKVRRLYDIANVLSSLNLIEKtqqvdSRKPAFRWLG 242
                   79****************************************************************9999999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.107.0E-261383IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.04E-161681IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.6E-291782IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.5E-211882IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.103.3E-23160243IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-32162242IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.5E-20163242IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467859.52E-13164242IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 387 aa     Download sequence    Send to blast
SGSGAAARAC RHHSYSRKQK SLGLLCSNFV ALYDRDDVET VGLDDAARRL GVERRRIYDI  60
VNVLESVGIL VRRAKNRYTW IGFEGVPAAL KELKERTLRE MSGLAPPPEE PSATNVSDDE  120
DEDDKLGDAD GDADSEKLSQ SLDNASDKPD APMCPLRSVD HRKEKSLGLL TQNFVKLFLT  180
MEVETVSLDE AARLLLGERH AESNMRTKVR RLYDIANVLS SLNLIEKTQQ VDSRKPAFRW  240
LGQAKRKEGA AVTVALPPNR KIMSSKRAFG TDITNIDNKR GKLVLETENK PKLMQAGSSM  300
LKTFESQLGQ GKSSGFVYGP FHPAGARKQE VDDQTVRENE TKNIQDWESL AVSFRPQYQN  360
HALNDLFGHY VEAWRSWYLD LTRESTS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A6e-39162343228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMLOC_67050.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3753580.0AK375358.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv3092B12.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020187543.10.0E2F transcription factor-like E2FE isoform X1
SwissprotQ8LSZ41e-105E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLF2EGT10.0F2EGT1_HORVV; Predicted protein
STRINGMLOC_67050.10.0(Hordeum vulgare)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-106DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]