PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MLOC_57580.4
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum
Family C2H2
Protein Properties Length: 184aa    MW: 20947.6 Da    PI: 9.3957
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MLOC_57580.4genomeIBSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.20.00123558123
                  EEETTTTEEESSHHHHHHHHHH.T CS
       zf-C2H2  1 ykCpdCgksFsrksnLkrHirt.H 23
                  +kC+ C+k  s+   +  H    H
  MLOC_57580.4 35 FKCHVCHKKLSTAGGMAIHVLQvH 58
                  89**********999999986655 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5080810.297665IPR003656Zinc finger, BED-type
SMARTSM003552.81134IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002801334IPR007087Zinc finger, C2H2
SMARTSM003550.0653558IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002803758IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009910Biological Processnegative regulation of flower development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0042803Molecular Functionprotein homodimerization activity
GO:0046872Molecular Functionmetal ion binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 184 aa     Download sequence    Send to blast
MGKKKKRVEK VFCYYCDREF DDEKILVQHQ KAKHFKCHVC HKKLSTAGGM AIHVLQVHKE  60
SVTKVPNAKP ERDSTEIEIF GMQGIPSDVL AAHYGEEEEP SPKVPKVEVP TIRPPIMPNY  120
PIGMPFPPRP YGAARPMYNP AMMVRPPIWP LQQPQPWFAQ QPAVSVPPMI AGHHMLWSPQ  180
GFLH
Functional Description ? help Back to Top
Source Description
UniProtSequence-specific DNA binding factor that recognizes the 5'-CCAAATTTTAAGTTT-3' sequence. Recruits the FRI-C complex to the FLC promoter. Required for FRI-mediated FLC activation, but has no effect on the expression of MAF1, MAF2, MAF3, MAF5, UFC and CO. Dispensable for the reactivation of FLC in early embryogenesis, but required to maintain high levels of FLC expression in later embryonic and vegetative development. {ECO:0000269|PubMed:17079264, ECO:0000269|PubMed:17138694, ECO:0000269|PubMed:19121105, ECO:0000269|PubMed:21282526}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMLOC_57580.4
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not regulated by photoperiod or vernalization. {ECO:0000269|PubMed:17079264, ECO:0000269|PubMed:17138694}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2481800.0AK248180.1 Hordeum vulgare subsp. vulgare cDNA clone: FLbaf137a02, mRNA sequence.
GenBankAK3580140.0AK358014.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv1067A04.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020177521.11e-121protein SUPPRESSOR OF FRI 4 isoform X2
SwissprotQ9C5G09e-68SUF4_ARATH; Protein SUPPRESSOR OF FRI 4
TrEMBLF2D2A71e-124F2D2A7_HORVV; Predicted protein
STRINGMLOC_57580.31e-125(Hordeum vulgare)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G30970.16e-56C2H2 family protein
Publications ? help Back to Top
  1. Ding L,Kim SY,Michaels SD
    FLOWERING LOCUS C EXPRESSOR family proteins regulate FLOWERING LOCUS C expression in both winter-annual and rapid-cycling Arabidopsis.
    Plant Physiol., 2013. 163(1): p. 243-52
    [PMID:23899645]
  2. Resentini F, et al.
    SUPPRESSOR OF FRIGIDA (SUF4) Supports Gamete Fusion via Regulating Arabidopsis EC1 Gene Expression.
    Plant Physiol., 2017. 173(1): p. 155-166
    [PMID:27920160]