PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MLOC_11665.6
Organism
Hordeum vulgare
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum
Family C2H2
Protein Properties Length: 223aa    MW: 24962.7 Da    PI: 6.5063
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MLOC_11665.6genomeIBSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H222.62.6e-07832123
                  EEET..TTTEEESSHHHHHHHHHHT CS
       zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                  ++Cp   Cgk Fs   nLk H++tH
  MLOC_11665.6  8 FVCPheGCGKAFSLDFNLKAHMKTH 32
                  89**********************9 PP
2zf-C2H216.72.1e-053863123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
       zf-C2H2  1 ykCp..dCgksFsrksnLkrHirt.H 23
                  + Cp   Cg++F++ s L+ H r  H
  MLOC_11665.6 38 HMCPypECGRRFTQESKLRAHFRAqH 63
                  689999***************99877 PP
3zf-C2H217.61.1e-0596121123
                   EEET..TTTEEESSHHHHHHHHHH.T CS
       zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                   y+Cp   Cgk + + + L+ H+++ H
  MLOC_11665.6  96 YVCPydGCGKAYIHEYKLNLHLKKeH 121
                   9**********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.604.3E-14332IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003554.3E-4832IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.739837IPR007087Zinc finger, C2H2
PROSITE patternPS0002801032IPR007087Zinc finger, C2H2
SuperFamilySSF576675.51E-101864No hitNo description
SMARTSM003550.00773863IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.0323863IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.0E-83860IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS0002804063IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.4E-988118IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576674.55E-691119No hitNo description
PROSITE profilePS501579.68196126IPR007087Zinc finger, C2H2
SMARTSM003550.001696121IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028098121IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 223 aa     Download sequence    Send to blast
MWEGEKNFVC PHEGCGKAFS LDFNLKAHMK THFADNYHMC PYPECGRRFT QESKLRAHFR  60
AQHEKNLGGP VMNPGGPHNT LKSPVTPPVP SADRPYVCPY DGCGKAYIHE YKLNLHLKKE  120
HPNHYSNAGA QAGSSRGTVS KNSRRSKPNL MTSMPLAKIP KRNGYTVPSS SVVTVPEEHQ  180
WPRKVLYEAD SEETEEEGDN MEEGGLGYRA GSGDDDDETE EEE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C7e-1345959114PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMLOC_11665.6
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3569600.0AK356960.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv1042P17.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020149434.11e-123uncharacterized zinc finger protein At4g06634 isoform X2
SwissprotQ2V3L35e-48YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLF2CZA41e-160F2CZA4_HORVV; Predicted protein
STRINGMLOC_11665.61e-167(Hordeum vulgare)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP20943899
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.25e-49C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]