PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G044552.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family E2F/DP
Protein Properties Length: 277aa    MW: 30765.9 Da    PI: 9.8409
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G044552.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP73.32.7e-2378157471
               E2F_TDP   4 ksLrlltqkflklleksee.givtlnevakeLvse...............dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                            +Lr++++    +++k e+ g++t+ eva+e+++e               d+kn+rRR+YD+lNVL+al++i++ +k+ei+wkg
  HL.SW.v1.0.G044552.1  78 GGLRQFSTI---VCKKLETkGRTTYGEVADEIIAEfggtvkespvsldefDEKNIRRRVYDALNVLMALDIITR-DKKEIQWKG 157
                           69*******...****9999******************************************************.*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM013722.7E-2675157IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.105.4E-3677162IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467859.79E-1878158IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.5E-2079157IPR003316E2F/DP family, winged-helix DNA-binding domain
SMARTSM011381.7E-11164264IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440741.33E-19165259No hitNo description
PfamPF087812.1E-12193234IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 277 aa     Download sequence    Send to blast
VHAKTLNSIS AAAPSGPPVN PLRLFIAIRT QSRSFSNKGS DTIMDQRHQG SANLPSDHTS  60
IKNHNAEKKK RPCKIIGGGL RQFSTIVCKK LETKGRTTYG EVADEIIAEF GGTVKESPVS  120
LDEFDEKNIR RRVYDALNVL MALDIITRDK KEIQWKGLPT QDVKGLEELK ATRMKLVNRI  180
GKKTAYLNDL KDQTSSHATV EIEISEDMQL VHFDFNSTPF SLHDDAYILK LLRRHQLPAE  240
SRDISSSSSA VSSSSSALAC KGTKPFYWNS EAHTQR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B3e-2877160991PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding and the transactivation activities of E2F proteins after heterodimerization. The complex DPA/E2FA promotes cell division and acts as a regulator of the endocycle. Positively regulates the activity of S phase-specific genes. {ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor ERF114. {ECO:0000269|PubMed:23616605}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024031258.11e-102transcription factor-like protein DPA isoform X1
SwissprotQ9FNY32e-63DPA_ARATH; Transcription factor-like protein DPA
TrEMBLA0A2P5DS855e-98A0A2P5DS85_TREOI; DP transcription factor
STRINGVIT_08s0007g00170.t012e-95(Vitis vinifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33213366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G02470.33e-65Transcription factor DP