PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G044380.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family C2H2
Protein Properties Length: 367aa    MW: 42588.6 Da    PI: 8.8452
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G044380.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H220.11.7e-066485223
                          EETTTTEEESSHHHHHHHHHHT CS
               zf-C2H2  2 kCpdCgksFsrksnLkrHirtH 23
                          +C+ Cg +F+   +Lk+H+++H
  HL.SW.v1.0.G044380.1 64 TCEECGLTFKKAAYLKQHMQSH 85
                          6*******************99 PP
2zf-C2H216.22.9e-0591115123
                           EEET..TTTEEESSHHHHHHHHHHT CS
               zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                           ++C+  dC  s++rk++L+rH+  H
  HL.SW.v1.0.G044380.1  91 HVCSvdDCRSSYRRKDHLTRHLLIH 115
                           799*******************998 PP
3zf-C2H212.50.00044120145123
                           EEET..TTTEEESSHHHHHHHHHH.T CS
               zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                           +kCp  +C+  Fs + n krH r  H
  HL.SW.v1.0.G044380.1 120 FKCPieNCKIEFSIQANVKRHVREkH 145
                           89*********************988 PP
4zf-C2H216.91.8e-05160184123
                           EEET..TTTEEESSHHHHHHHHHHT CS
               zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                           ++C+   Cgk F  +s L++H ++H
  HL.SW.v1.0.G044380.1 160 HVCQevGCGKAFAYPSRLRKHEQSH 184
                           789999***************9998 PP
5zf-C2H214.78.7e-05252275323
                           ET..TTTEEESSHHHHHHHHHH.T CS
               zf-C2H2   3 Cp..dCgksFsrksnLkrHirt.H 23 
                           C    C  +Fs+ksnL++H++  H
  HL.SW.v1.0.G044380.1 252 CLykGCLHTFSTKSNLNQHLKAvH 275
                           66679***************9877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM00355271739IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.2976390IPR007087Zinc finger, C2H2
SMARTSM003550.00556385IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.608.5E-66484IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.19E-1064115No hitNo description
PROSITE patternPS0002806585IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.2E-1285117IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.49491120IPR007087Zinc finger, C2H2
SMARTSM003550.03791115IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028093115IPR007087Zinc finger, C2H2
SuperFamilySSF576672.64E-7101155No hitNo description
Gene3DG3DSA:3.30.160.603.0E-4118143IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.448120150IPR007087Zinc finger, C2H2
SMARTSM003550.019120145IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280122145IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.7E-8154184IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576671.15E-5156186No hitNo description
PROSITE profilePS5015711.136160189IPR007087Zinc finger, C2H2
SMARTSM003550.0034160184IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280162184IPR007087Zinc finger, C2H2
SMARTSM003556.9192217IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280194217IPR007087Zinc finger, C2H2
CDDcd029800.0089212257No hitNo description
SMARTSM0035512220241IPR015880Zinc finger, C2H2-like
SuperFamilySSF576677.95E-8231292No hitNo description
SMARTSM003550.0088250275IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.697250280IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.3E-4251277IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280252275IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.609.8E-6278302IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003556.8281307IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280283307IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008097Molecular Function5S rRNA binding
GO:0046872Molecular Functionmetal ion binding
GO:0080084Molecular Function5S rDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 367 aa     Download sequence    Send to blast
MVEAGEERPI FRDIRRYFCD YCGICRSKKT LISSHILTHH KEELDKVKAE GESSTEGVEE  60
SKNTCEECGL TFKKAAYLKQ HMQSHSLERP HVCSVDDCRS SYRRKDHLTR HLLIHKGKLF  120
KCPIENCKIE FSIQANVKRH VREKHNEDRP STSTEREKQH VCQEVGCGKA FAYPSRLRKH  180
EQSHVKLESI EALCVEPGCM KIFTNEQCLR DHIQLCHQHI TCEVCGSKHL KKNMKRHLRS  240
HEEKVSVESI KCLYKGCLHT FSTKSNLNQH LKAVHFNKKP YVCGFSGCGK RFAYKHVRDN  300
HEKRSCHIYA HGDFEEADEQ FRSRPRGGRK RKYPSFVDLL VRKRITPRND LDGSFECLDS  360
FSCGGE*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2i13_A4e-146024419187Aart
2i13_B4e-146024419187Aart
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1229235LKKNMKR
2323331RPRGGRKRK
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00229DAPTransfer from AT1G72050Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015867533.10.0transcription factor IIIA isoform X1
RefseqXP_024924686.10.0transcription factor IIIA isoform X1
SwissprotQ84MZ41e-139TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A2P5CW950.0A0A2P5CW95_PARAD; TFIIH C1-like domain containing protein
STRINGXP_010104482.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF30693370
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.21e-141transcription factor IIIA