PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G040909.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family TALE
Protein Properties Length: 123aa    MW: 14648.9 Da    PI: 10.2245
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G040909.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox29.99.4e-1062962155
                          HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
              Homeobox 21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55
                          + +yp+++++ +LA+ +gL+++q+ +WF N+R ++
  HL.SW.v1.0.G040909.1 62 RWPYPTETDKIHLAELTGLDQKQINNWFINQRKRH 96
                          569*****************************985 PP
2ELK39.21.5e-131637122
                   ELK  1 ELKhqLlrKYsgyLgsLkqEFs 22
                          ELK+ LlrKYsgy+++Lk+EFs
  HL.SW.v1.0.G040909.1 16 ELKDKLLRKYSGYISTLKHEFS 37
                          9********************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5121310.7721636IPR005539ELK domain
SMARTSM011888.9E-81637IPR005539ELK domain
PfamPF037892.1E-111637IPR005539ELK domain
PROSITE profilePS5007112.3573699IPR001356Homeobox domain
SuperFamilySSF466891.75E-2037109IPR009057Homeodomain-like
SMARTSM003895.7E-1138103IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.604.3E-2841100IPR009057Homeodomain-like
PfamPF059201.4E-165695IPR008422Homeobox KN domain
CDDcd000863.34E-106299No hitNo description
PROSITE patternPS0002707497IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 123 aa     Download sequence    Send to blast
MEGGDTLRMI TQEDRELKDK LLRKYSGYIS TLKHEFSKKK KKGKLPKQAR QILLDWWSLH  60
YRWPYPTETD KIHLAELTGL DQKQINNWFI NQRKRHWKPP ENMQVAIMEA HSLYGSSICH  120
NQ*
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010109305.12e-60homeobox protein knotted-1-like 4
SwissprotQ84JS62e-46KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A2P5DG042e-69A0A2P5DG04_PARAD; Octamer-binding transcription factor
STRINGXP_010109305.19e-60(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF62034125
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.22e-42KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]