PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G032298.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family TALE
Protein Properties Length: 339aa    MW: 37637 Da    PI: 4.8748
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G032298.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox27.65e-092783122155
                           HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
              Homeobox  21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                           + +yp+++++ +LA+ +gL+++q+ +WF N+R ++
  HL.SW.v1.0.G032298.1 278 RWPYPTETDKIHLAELTGLDQKQINNWFINQRKRH 312
                           569*****************************885 PP
2ELK37.26.1e-13232253122
                   ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                           ELK+ LlrKYsgy+++Lk+EFs
  HL.SW.v1.0.G032298.1 232 ELKDKLLRKYSGYISTLKHEFS 253
                           9********************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012551.9E-2283127IPR005540KNOX1
PfamPF037902.6E-2185126IPR005540KNOX1
SMARTSM012569.5E-20134185IPR005541KNOX2
PfamPF037917.7E-22139183IPR005541KNOX2
SMARTSM011888.9E-8232253IPR005539ELK domain
PROSITE profilePS5121310.772232252IPR005539ELK domain
PfamPF037898.5E-11232253IPR005539ELK domain
PROSITE profilePS5007112.357252315IPR001356Homeobox domain
SuperFamilySSF466892.44E-19253322IPR009057Homeodomain-like
SMARTSM003895.7E-11254319IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.604.4E-27257315IPR009057Homeodomain-like
CDDcd000866.50E-12264315No hitNo description
PfamPF059207.9E-16272311IPR008422Homeobox KN domain
PROSITE patternPS000270290313IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 339 aa     Download sequence    Send to blast
MMDNDLYGLG GYSEQSSMAP PHGLVAPAAD DYLLSSTTLE AVAGFDDHDR VHHAFGSDSI  60
FPAPPSSAVS DAASMATSDD VSCEIRAKIA THPLYPKLLE AYIDCRKVGA PPELASSLDE  120
IRRESEVSDN RTAASTFVVS DPELDDFMES YCGILVKYKS DLLRPFDEAT SFLNEMQAQL  180
NSLSCSTTTT TSTSYVSDGE GGGGSSEEEH ELSGGEMEGG DTLRMITQED RELKDKLLRK  240
YSGYISTLKH EFSKKKKKGK LPKQARQILL DWWSLHYRWP YPTETDKIHL AELTGLDQKQ  300
INNWFINQRK RHWKPPENMQ VAIIEAHSLY GSSICHNQ*
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024929478.11e-131homeobox protein knotted-1-like 6
SwissprotQ84JS61e-105KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A2P5DG041e-162A0A2P5DG04_PARAD; Octamer-binding transcription factor
STRINGXP_008393011.11e-112(Malus domestica)
STRINGXP_002511373.11e-113(Ricinus communis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF62034125
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.16e-84KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]