PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G031889.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family HSF
Protein Properties Length: 301aa    MW: 33380.1 Da    PI: 4.8234
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G031889.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind118.24.7e-37101012102
                           HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXX CS
          HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgk 90 
                           Fl+k+y++++d+ ++++isw+eng++fvv+++ +fa+++LpkyFkh+nf+SFvRQLn+YgF+kv  e+         weF++++F++g+
  HL.SW.v1.0.G031889.1  10 FLTKTYQLVDDPITDDVISWNENGTAFVVWKTADFARDLLPKYFKHNNFSSFVRQLNTYGFRKVVPEK---------WEFANENFRRGQ 89 
                           9****************************************************************999.........************ PP

                           XXXXXXXXXXXX CS
          HSF_DNA-bind  91 kellekikrkks 102
                           kell++i+r+k+
  HL.SW.v1.0.G031889.1  90 KELLSEIRRRKT 101
                           *********986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.5E-38393IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004151.6E-61699IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF467858.3E-34799IPR011991Winged helix-turn-helix DNA-binding domain
PRINTSPR000562.4E-211033IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004471.7E-321099IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.4E-214860IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043404973IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.4E-216173IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009408Biological Processresponse to heat
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 301 aa     Download sequence    Send to blast
MAQRSVPAPF LTKTYQLVDD PITDDVISWN ENGTAFVVWK TADFARDLLP KYFKHNNFSS  60
FVRQLNTYGF RKVVPEKWEF ANENFRRGQK ELLSEIRRRK TVATSSTPAQ ISPEGKSAGE  120
GSSSPSNSGE DLGSTSMSSP DSKSPGSVET AAIAMTQFAD LSGENEKLKK DNEVLSSELA  180
QTKKQCDELI AFLTEYMKVG PDQINRIMRQ GNCTSINGGK DCDDDENEVV ESSEEEEEEE  240
EKGENEEGLK LFGVWVKGKE NKKRNRNDGA GFTGPPHPKE MKGVDFHAPP MIMKSSKVCN  300
*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B2e-27510125131Heat shock factor protein 1
5d5v_B2e-27510125131Heat shock factor protein 1
5d5v_D2e-27510125131Heat shock factor protein 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024019588.11e-154heat shock factor protein HSF24
SwissprotP223351e-109HSF24_SOLPE; Heat shock factor protein HSF24
TrEMBLA0A2P5ATC81e-155A0A2P5ATC8_PARAD; Heat shock transcription factor
STRINGEOX914071e-145(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF71143247
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G36990.14e-86heat shock factor 4
Publications ? help Back to Top
  1. Scharf KD, et al.
    Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF.
    EMBO J., 1990. 9(13): p. 4495-501
    [PMID:2148291]