PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G029402.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family C2H2
Protein Properties Length: 345aa    MW: 37274.5 Da    PI: 7.1766
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G029402.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.70.000813659123
                          EEETTTTEEESSHHHHHHHHHH.T CS
               zf-C2H2  1 ykCpdCgksFsrksnLkrHirt.H 23
                          +kC+ C+k  s+ s +  H    H
  HL.SW.v1.0.G029402.1 36 FKCHVCHKKLSTASGMAIHVLQvH 59
                          89***************9987655 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5080812.221766IPR003656Zinc finger, BED-type
SMARTSM00355201235IPR015880Zinc finger, C2H2-like
SuperFamilySSF576678.1E-51261No hitNo description
PROSITE patternPS0002801435IPR007087Zinc finger, C2H2
SMARTSM003550.13659IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002803859IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009910Biological Processnegative regulation of flower development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0042803Molecular Functionprotein homodimerization activity
GO:0046872Molecular Functionmetal ion binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 345 aa     Download sequence    Send to blast
MGKKKKRVAS KVWCYYCDRE FDDEKILVQH QKAKHFKCHV CHKKLSTASG MAIHVLQVHK  60
ESVTKVPNAK SGRESTEIEI YGMQGIPDDI LAAHYGEEDE DAPSKVAKGD ILSTPLGPMV  120
PGSMSIAYPP QPALGAMPPM YNSSVPVPPN AWPIPRLQHW YPHSTAVSIP QSAPLGGYAQ  180
QPLFPVQNVR PPMPSSVPPA LQPVQMNPGL PTSAPPIPVS QPLFPVGGNN NVPTQNVAFS  240
TSVLSTSIPP SSTVDDRASL DAHSGVQLIN SHSYASGPNT GGPSIGPPPV ITNKTPATQP  300
ATNEVYLVWD DEAMSMEERR MSLSKYQVHD ETSQIQLFTH CFLL*
Functional Description ? help Back to Top
Source Description
UniProtSequence-specific DNA binding factor that recognizes the 5'-CCAAATTTTAAGTTT-3' sequence. Recruits the FRI-C complex to the FLC promoter. Required for FRI-mediated FLC activation, but has no effect on the expression of MAF1, MAF2, MAF3, MAF5, UFC and CO. Dispensable for the reactivation of FLC in early embryogenesis, but required to maintain high levels of FLC expression in later embryonic and vegetative development. {ECO:0000269|PubMed:17079264, ECO:0000269|PubMed:17138694, ECO:0000269|PubMed:19121105, ECO:0000269|PubMed:21282526}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not regulated by photoperiod or vernalization. {ECO:0000269|PubMed:17079264, ECO:0000269|PubMed:17138694}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024020148.10.0protein SUPPRESSOR OF FRI 4 isoform X2
RefseqXP_024020150.10.0protein SUPPRESSOR OF FRI 4 isoform X4
SwissprotQ9C5G01e-136SUF4_ARATH; Protein SUPPRESSOR OF FRI 4
TrEMBLA0A2P5EUN60.0A0A2P5EUN6_TREOI; TFIIH C1-like domain containing protein
STRINGXP_010094610.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF966255
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G30970.11e-139C2H2 family protein
Publications ? help Back to Top
  1. Ding L,Kim SY,Michaels SD
    FLOWERING LOCUS C EXPRESSOR family proteins regulate FLOWERING LOCUS C expression in both winter-annual and rapid-cycling Arabidopsis.
    Plant Physiol., 2013. 163(1): p. 243-52
    [PMID:23899645]
  2. Resentini F, et al.
    SUPPRESSOR OF FRIGIDA (SUF4) Supports Gamete Fusion via Regulating Arabidopsis EC1 Gene Expression.
    Plant Physiol., 2017. 173(1): p. 155-166
    [PMID:27920160]