PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G026672.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family TALE
Protein Properties Length: 679aa    MW: 73797 Da    PI: 7.2415
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G026672.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox28.82.2e-094594961954
                           HHH..SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHH CS
              Homeobox  19 Fek..nrypsaeereeLAkklgLterqVkvWFqNrRak 54 
                           Fe   ++yp+ +++  LAk++gL+ +qV++WF N R +
  HL.SW.v1.0.G026672.1 459 FEHflHPYPTDTDKLMLAKQTGLSRSQVSNWFINARVR 496
                           554459******************************88 PP
2BELL107.58.6e-35328395572
                  BELL   5 lqkkkakLlslleeVdkrYkqyveqlqtvissFeavaglgsakpYtslAlkaiSrhFrcLkdaiaeqi 72 
                            +kkk++L+s+l+eV++rYkqy++q+qtv+ sFe vaglg+a+pY++lA ka+++hF+cLk+ai++q+
  HL.SW.v1.0.G026672.1 328 SRKKKSRLISMLDEVYRRYKQYYQQMQTVVTSFEYVAGLGNAAPYANLAVKAMTKHFKCLKNAIMDQL 395
                           689**************************************************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM005747.5E-50254393IPR006563POX domain
PfamPF075263.5E-39259392IPR006563POX domain
PROSITE profilePS5007112.098437500IPR001356Homeobox domain
SMARTSM003893.4E-10440504IPR001356Homeobox domain
CDDcd000864.75E-13440501No hitNo description
SuperFamilySSF466895.99E-17442507IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.2E-27443504IPR009057Homeodomain-like
PfamPF059201.2E-18457496IPR008422Homeobox KN domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010076Biological Processmaintenance of floral meristem identity
GO:0010077Biological Processmaintenance of inflorescence meristem identity
GO:0010089Biological Processxylem development
GO:0010154Biological Processfruit development
GO:0010223Biological Processsecondary shoot formation
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0048457Biological Processfloral whorl morphogenesis
GO:0048645Biological Processorgan formation
GO:0080006Biological Processinternode patterning
GO:0005634Cellular Componentnucleus
GO:0005829Cellular Componentcytosol
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 679 aa     Download sequence    Send to blast
MAEGFEPYHV PQQSRRDKLR VVVTQSSSHP ASGSACIDAA ANFHGSGGLL PLATSYDPTA  60
AISSDLLSCT PHPHHNHHQH QHHHHHQLSH AAVGKGVSSP GCVDVSKEEG VVNLMGLVNG  120
SSSTSSTSNF RNPFMDPMTS IQDINSNPFL FSSQTLQSLR DFEQQGFNNG VFKPEPLSLS  180
LSSHHDPTRI QNTSNSTNSN QLPLELNLQR FGSAFYGGGS ATNANTTAAA IVGGGSGAGD  240
GVGSRSSAPL GPFTGYSSIL KGSRFLRPAQ QLLEEFCNVG DRVVYAENLS ADPSLLESPV  300
EGLSSGTGGV NVDDVELSSG VSDGGESSRK KKSRLISMLD EVYRRYKQYY QQMQTVVTSF  360
EYVAGLGNAA PYANLAVKAM TKHFKCLKNA IMDQLQFSNK DNSHTNHGKE EVPTFRNSNR  420
GLYSQRPIHG SGFLEHQPVW RPQRGLPERA VTVLRAWLFE HFLHPYPTDT DKLMLAKQTG  480
LSRSQVSNWF INARVRLWKP MVEEIHMLET RQAQKASHRE DPNATRPNTH EHVASASNLT  540
SENPSTSMHR VHDTTLKRSR NEVPAVMDAA GASEEMNMSY DNLPSHLHHH QVGVAAPAMN  600
MAGVGSNGVS LTLGLHQNNG TIGLSEPFPI NAAQRFGLGL EGNNEGYVMG AFEAQNRHFG  660
RDHHHHVMGG QLLHDFVG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4xrm_A3e-16446504563Homeobox protein Meis2
4xrm_B3e-16446504563Homeobox protein Meis2
4xrs_A3e-16446503158Homeobox protein Meis1
4xrs_B3e-16446503158Homeobox protein Meis1
5bng_A3e-16446504159Homeobox protein Meis2
5bng_B3e-16446504159Homeobox protein Meis2
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that is involved in the preservation of the spiral phyllotactic arrangement leading to a regular pattern of organ initiation. Required for maintenance of stem cell fate in the shoot apical meristem, and is essential for specifying floral primordia and establishing early internode patterning events during inflorescence development. Acts as transcription repressor of AG expression in floral and inflorescence meristems. Is also responsive of the nuclear import of SHOOT MERISTEMLESS (STM). In the fruit, plays a central role in patterning by negatively regulating SHP expression in order to prevent replum cells from adopting a valve margin cell fate. {ECO:0000269|PubMed:12874117, ECO:0000269|PubMed:12897247, ECO:0000269|PubMed:13678595, ECO:0000269|PubMed:15019989, ECO:0000269|PubMed:15120075, ECO:0000269|PubMed:15155890, ECO:0000269|PubMed:16741748}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010654234.10.0PREDICTED: BEL1-like homeodomain protein 9
SwissprotQ9LZM81e-114BLH9_ARATH; BEL1-like homeodomain protein 9
TrEMBLA0A2P5CFU70.0A0A2P5CFU7_PARAD; Knotted like homeodomain transcription factor
STRINGVIT_08s0007g01290.t010.0(Vitis vinifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF28103373
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G02030.18e-99TALE family protein
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Pabón-Mora N,Wong GK,Ambrose BA
    Evolution of fruit development genes in flowering plants.
    Front Plant Sci, 2014. 5: p. 300
    [PMID:25018763]
  3. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]
  4. Andrés F, et al.
    Floral Induction in Arabidopsis by FLOWERING LOCUS T Requires Direct Repression of BLADE-ON-PETIOLE Genes by the Homeodomain Protein PENNYWISE.
    Plant Physiol., 2015. 169(3): p. 2187-99
    [PMID:26417007]
  5. Bencivenga S,Serrano-Mislata A,Bush M,Fox S,Sablowski R
    Control of Oriented Tissue Growth through Repression of Organ Boundary Genes Promotes Stem Morphogenesis.
    Dev. Cell, 2016. 39(2): p. 198-208
    [PMID:27666746]
  6. Sehra B,Franks RG
    Redundant CArG Box Cis-motif Activity Mediates SHATTERPROOF2 Transcriptional Regulation during Arabidopsis thaliana Gynoecium Development.
    Front Plant Sci, 2017. 8: p. 1712
    [PMID:29085379]
  7. Simonini S,Stephenson P,Østergaard L
    A molecular framework controlling style morphology in Brassicaceae.
    Development, 2018.
    [PMID:29440299]