PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | HL.SW.v1.0.G026215.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
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Family | E2F/DP | ||||||||
Protein Properties | Length: 516aa MW: 58700.8 Da PI: 9.9794 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 43.3 | 5.9e-14 | 182 | 212 | 39 | 71 |
E2F_TDP 39 vknkrRRiYDilNVLealnliekkekneirwkg 71 v +rRRiYDi+NVLe+++++++k+kn+++wkg HL.SW.v1.0.G026215.1 182 V--ERRRIYDIVNVLESVGVLARKAKNQYTWKG 212 4..8***************************98 PP | |||||||
2 | E2F_TDP | 75.2 | 6.7e-24 | 282 | 362 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL lltq+f+kl+ +++ + ++l+e+ak L+ + +++k+RR+YDi+NVL+++nliek ++k+++rw g HL.SW.v1.0.G026215.1 282 RREKSLALLTQNFVKLFVCTSVDLISLDEAAKLLLGDahnssIMRTKVRRLYDIANVLSSMNLIEKthtsdTRKPAFRWLG 362 689**************************************999**************************99*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
SMART | SM01372 | 8.8E-7 | 135 | 212 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 3.26E-9 | 177 | 213 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 2.3E-11 | 180 | 212 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 5.9E-13 | 182 | 214 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 4.2E-22 | 278 | 363 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 7.2E-31 | 282 | 362 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 6.0E-19 | 284 | 362 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 5.89E-13 | 284 | 363 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 516 aa Download sequence Send to blast |
MFTLLRKAPL KKIPSQALKP IISIPCRSLS AMPPAEAAQV FAMTEIILKA APEALPETLL 60 NPTLDWTPDL IDKILKRLWN HGPKALQFFR VLDHHPNYAH SSSSFDHAID LAARLRDYKT 120 VWTLVARMRS RRLGPGPKTF AIIAERRDLK IVQWRRHRPL SPEPTPLNTT LIAGSRSLSA 180 WVERRRIYDI VNVLESVGVL ARKAKNQYTW KGFEAIPKAL KELKDEGLKE NFSSFDGNDD 240 AKVSDDEEDD ERISDPRTES QPDKLNPNLN LKSSASSKPE NRREKSLALL TQNFVKLFVC 300 TSVDLISLDE AAKLLLGDAH NSSIMRTKVR RLYDIANVLS SMNLIEKTHT SDTRKPAFRW 360 LGFEGRGRAN HNSSAHDSVV TESRKRSFGA DITNISFKRN KMDSLVGESL NMNFSKQKQV 420 KQESYVEEID RITFEEDSNE STKSYQFGPF APVTIARVGA SENNNPRKVH DWEKLASIYR 480 PQYQNQALND LFSHYMEAWK TWYSEVAEKN PIKIS* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 7e-30 | 182 | 354 | 43 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_015879579.1 | 1e-179 | E2F transcription factor-like E2FE isoform X2 | ||||
Refseq | XP_024924831.1 | 1e-179 | E2F transcription factor-like E2FE isoform X2 | ||||
Swissprot | Q8LSZ4 | 1e-115 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | W9SXR3 | 1e-175 | W9SXR3_9ROSA; E2F transcription factor-like E2FE | ||||
STRING | XP_010111971.1 | 1e-176 | (Morus notabilis) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF3668 | 33 | 66 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 1e-118 | DP-E2F-like 1 |
Publications ? help Back to Top | |||
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