PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G025681.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family ARF
Protein Properties Length: 408aa    MW: 46076 Da    PI: 8.99
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G025681.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B376.14e-24120220198
                           EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEE CS
                    B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvF 82 
                           f kvlt+sd+++ g +++pkk ae++       + ++ +  tl+ +d +gr W++++ yr+++ r++lt+GW++Fv+a++L +gD++vF
  HL.SW.v1.0.G025681.1 120 FSKVLTQSDAHNGGGFSVPKKLAETIfpaldynDDPPVQ--TLRARDVQGRIWRFRHVYRGRPLRHLLTTGWSKFVNAKKLVAGDSIVF 206
                           88*****************************96555555..9*********************************************** PP

                           EE-SSSEE..EEEEE- CS
                    B3  83 kldgrsefelvvkvfr 98 
                           +  + +++e  v+++r
  HL.SW.v1.0.G025681.1 207 S--KAENGEVSVGIRR 220
                           *..5599999****98 PP
2Auxin_resp752e-25238323183
            Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk..vkvsvGmRfkmafetedsserrl.sGtvvgvsdldpvrWpnSkWrsLk 83 
                           a++ a + ++F+v Y+P  +t+eF+v++  v +a+   +++ +G Rfkmafe+edss+ ++ +G + +  d +p+rW +S Wr+L+
  HL.SW.v1.0.G025681.1 238 AVNLAVQVKPFQVSYYPNNGTTEFCVEATAVYAAVMrrSQLGPGARFKMAFESEDSSRVSWfMGSINSNVDDQPSRWFGSLWRLLQ 323
                           678888999*******************999998764678999*****************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.109.8E-36116225IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019362.75E-28118223IPR015300DNA-binding pseudobarrel domain
CDDcd100171.42E-20119220No hitNo description
PfamPF023625.6E-21120220IPR003340B3 DNA binding domain
PROSITE profilePS5086313.634120222IPR003340B3 DNA binding domain
SMARTSM010198.2E-19120222IPR003340B3 DNA binding domain
PfamPF065075.8E-21238323IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 408 aa     Download sequence    Send to blast
MNEPGEAGER RNVVDPLLWH ACAGRLVHVP PVNANVFYFP QGHAEHAGAN ADYLAACRVP  60
PNIHCRVTAV EFNVELDSDE VFTRISLVPL PIEAYIEAIN RDWVDDVLGG IVNLERPQFF  120
SKVLTQSDAH NGGGFSVPKK LAETIFPALD YNDDPPVQTL RARDVQGRIW RFRHVYRGRP  180
LRHLLTTGWS KFVNAKKLVA GDSIVFSKAE NGEVSVGIRR VKRDNRVGRM RAESAIEAVN  240
LAVQVKPFQV SYYPNNGTTE FCVEATAVYA AVMRRSQLGP GARFKMAFES EDSSRVSWFM  300
GSINSNVDDQ PSRWFGSLWR LLQVTWDGGD IKFVRCINPW LVRVVSTHTI QNNDRHRDRH  360
RDRHRDRDRD GTHAAKQLEK STNTENNNNQ ILHLFGVRID TGQKSCL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A5e-74634943394Auxin response factor 5
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1358368RHRDRHRDRDR
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008243944.11e-120PREDICTED: auxin response factor 18-like isoform X1
RefseqXP_008243945.11e-120PREDICTED: auxin response factor 18-like isoform X2
RefseqXP_021981621.11e-121auxin response factor 18-like
RefseqXP_021981622.11e-121auxin response factor 18-like
RefseqXP_021981623.11e-121auxin response factor 18-like
RefseqXP_021981624.11e-121auxin response factor 18-like
SwissprotQ93YR91e-116ARFP_ARATH; Auxin response factor 16
TrEMBLA0A251TSZ71e-119A0A251TSZ7_HELAN; Auxin response factor
TrEMBLA0A314ZP651e-119A0A314ZP65_PRUYE; Auxin response factor
STRINGcassava4.1_004716m1e-120(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF15884610
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G30080.11e-119auxin response factor 16
Publications ? help Back to Top
  1. Yang ZB, et al.
    TAA1-regulated local auxin biosynthesis in the root-apex transition zone mediates the aluminum-induced inhibition of root growth in Arabidopsis.
    Plant Cell, 2014. 26(7): p. 2889-904
    [PMID:25052716]
  2. Bennett T,van den Toorn A,Willemsen V,Scheres B
    Precise control of plant stem cell activity through parallel regulatory inputs.
    Development, 2014. 141(21): p. 4055-64
    [PMID:25256342]
  3. Zhang GZ, et al.
    Ectopic expression of UGT75D1, a glycosyltransferase preferring indole-3-butyric acid, modulates cotyledon development and stress tolerance in seed germination of Arabidopsis thaliana.
    Plant Mol. Biol., 2016. 90(1-2): p. 77-93
    [PMID:26496910]
  4. Ye Y, et al.
    Germostatin resistance locus 1 encodes a PHD finger protein involved in auxin-mediated seed dormancy and germination.
    Plant J., 2016. 85(1): p. 3-15
    [PMID:26611158]
  5. Liu Z, et al.
    Repression of callus initiation by the miRNA-directed interaction of auxin-cytokinin in Arabidopsis thaliana.
    Plant J., 2016. 87(4): p. 391-402
    [PMID:27189514]
  6. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  7. Wójcik AM,Nodine MD,Gaj MD
    miR160 and miR166/165 Contribute to the LEC2-Mediated Auxin Response Involved in the Somatic Embryogenesis Induction in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 2024
    [PMID:29321785]
  8. Lin JS, et al.
    MicroRNA160 Modulates Plant Development and Heat Shock Protein Gene Expression to Mediate Heat Tolerance in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 68
    [PMID:29449855]