PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G023154.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family bHLH
Protein Properties Length: 623aa    MW: 69316.8 Da    PI: 6.6021
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G023154.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.45.2e-13453499455
                           HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                   HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                           +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  HL.SW.v1.0.G023154.1 453 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYINELQ 499
                           799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142152.1E-5653241IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.047449498IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.49E-18452516IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.38E-14452503No hitNo description
Gene3DG3DSA:4.10.280.101.4E-18453512IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.8E-10453499IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.0E-16455504IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 623 aa     Download sequence    Send to blast
MKTELGFGGS GVWNDEDKTM VQAVLGTRAF DYLITSSVTN ENLLMAVGSD ENLQNKLSDL  60
VERPNASNFS WNYAIFWQIS RSKSGDWVLG WGDGSCREPR EGEESEATRF FNLRLEDETQ  120
QRMRKRVLQK LHNLFGGSDE DNYALGLDRV TDTEIFFLAS MYFSFPRGEG GPGKCYASGK  180
HLWLLDALKS SSDYCVRSFL AKSAGIQTIV LVPTEVGVVE LGSVRSVGES LELLQSVRSL  240
FSTQSSLVRV SKPMAMLPMM AEKRDENVNL TNSGILERNE SVGVHKIFGQ DLNAGAVARP  300
HYREKLAIRK LEERPWDLYP NGNGSRIAFS SPRNGIPGST WPHSLQGVKQ QGNPTEIYAS  360
QSPGSNNIQE IVNGVREDFR LNNYQPQKQV QMQIDFSGAT SRSTVINHRP TSAESEHSDV  420
EASCKEERPS TADERRPRKR GRKPANGREE PLNHVEAERQ RREKLNQRFY ALRAVVPNIS  480
KMDKASLLGD AIAYINELQA KLKAMEAERE KVGSSSTAAA METNNPDMEI QSRVPDVDVK  540
VVNDEVIVRV SCHLDSHPAS RVIQAFKEAQ ITVVDSKFTT VNDTVFHDFV IKSQGSEQLT  600
KEKLVAAFSI EANSLRTLSS VG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A7e-30447522277Transcription factor MYC2
5gnj_B7e-30447522277Transcription factor MYC2
5gnj_E7e-30447522277Transcription factor MYC2
5gnj_F7e-30447522277Transcription factor MYC2
5gnj_G7e-30447522277Transcription factor MYC2
5gnj_I7e-30447522277Transcription factor MYC2
5gnj_M7e-30447522277Transcription factor MYC2
5gnj_N7e-30447522277Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1434442RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024024130.10.0LOW QUALITY PROTEIN: transcription factor bHLH13
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A2P5FHN30.0A0A2P5FHN3_TREOI; Basic helix-loop-helix transcription factor
STRINGXP_010100724.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF54483254
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]