PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G023068.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family NF-X1
Protein Properties Length: 626aa    MW: 69929.6 Da    PI: 8.1245
Description NF-X1 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G023068.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-NF-X118.64e-06190208120
              zf-NF-X1   1 CGkHkCqklCHeGpCppCpq 20 
                           CG H+C  lCH+GpCp+Cp+
  HL.SW.v1.0.G023068.1 190 CG-HRCLLLCHPGPCPSCPK 208
                           **.***************96 PP
2zf-NF-X120.11.3e-06242260119
              zf-NF-X1   1 CGkHkCqklCHeGpCppCp 19 
                           CG H+C+ +CH GpC pC+
  HL.SW.v1.0.G023068.1 242 CGDHPCSDICHDGPCRPCK 260
                           ******************8 PP
3zf-NF-X117.77.8e-06403422120
              zf-NF-X1   1 CGkHkCqklCHeGpCppCpq 20 
                           CG+H C + C+ G+CppC++
  HL.SW.v1.0.G023068.1 403 CGRHACRRRCCDGDCPPCSE 422
                           ******************85 PP
4zf-NF-X1192.9e-06424448119
              zf-NF-X1   1 CG......kHkCqklCHeGpCppCp 19 
                           CG      +HkCq++CH+GpC pCp
  HL.SW.v1.0.G023068.1 424 CGrklrckNHKCQSPCHRGPCAPCP 448
                           777777779***************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF578503.96E-571150No hitNo description
PROSITE patternPS01359077143IPR019786Zinc finger, PHD-type, conserved site
CDDcd060089.56E-6178226No hitNo description
PfamPF014220.0011190207IPR000967Zinc finger, NF-X1-type
SMARTSM004380.012190208IPR000967Zinc finger, NF-X1-type
CDDcd060082.05E-8232280No hitNo description
PfamPF014221.6E-4242260IPR000967Zinc finger, NF-X1-type
SMARTSM004388.5E-4242261IPR000967Zinc finger, NF-X1-type
CDDcd060081.12E-8286326No hitNo description
PfamPF014220.37296314IPR000967Zinc finger, NF-X1-type
SMARTSM004380.002296315IPR000967Zinc finger, NF-X1-type
CDDcd060081.65E-8340389No hitNo description
PfamPF014220.001350369IPR000967Zinc finger, NF-X1-type
SMARTSM004380.025350370IPR000967Zinc finger, NF-X1-type
CDDcd060081.69E-8393441No hitNo description
PfamPF014225.9E-4403421IPR000967Zinc finger, NF-X1-type
SMARTSM004380.013403422IPR000967Zinc finger, NF-X1-type
CDDcd060081.71E-11420468No hitNo description
PfamPF014222.9E-4424448IPR000967Zinc finger, NF-X1-type
SMARTSM004380.0012430449IPR000967Zinc finger, NF-X1-type
SMARTSM0043839487508IPR000967Zinc finger, NF-X1-type
PfamPF014223.3497507IPR000967Zinc finger, NF-X1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0007623Biological Processcircadian rhythm
GO:0009651Biological Processresponse to salt stress
GO:0009908Biological Processflower development
GO:0010310Biological Processregulation of hydrogen peroxide metabolic process
GO:0042335Biological Processcuticle development
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000037Biological Processregulation of stomatal complex patterning
GO:0005634Cellular Componentnucleus
GO:0000987Molecular Functioncore promoter proximal region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 626 aa     Download sequence    Send to blast
MMPDQLRRSM AEPPLSDSDA DSDNGHPGCE HSRRHADLSD SIFRSYFEFT GRSLTTPADL  60
SKIQSFLTSS SSGALSCLIC LERIRPSDPT WSCNSLCFAV FHLFCIQSWA RQSSDLAALR  120
ASTRLPITAN RAAEVSVWNC PKCRFEYTQS QIPKTYFCFC GKLENPPSDD PWVLPHSCGE  180
VCDRSLMHDC GHRCLLLCHP GPCPSCPKLV RSRCFCGSVE DVRRCGFKNF SCNKVCSKLL  240
DCGDHPCSDI CHDGPCRPCK VRGVYWCQCG KKEEERECCD RVNFRCENPC NEMLSCRRHV  300
CSKGCHSGEC GPCPLQGKRT CPCGKRIHEG MSCDVAVPLC GSTCDKVLTC GYHRCPERCH  360
RGPCIETCRI VVIKLCRCGS LKKEVPCYQD MACERKCQKL RDCGRHACRR RCCDGDCPPC  420
SEICGRKLRC KNHKCQSPCH RGPCAPCPVM VTISCACGET HFEVPCGTEM DQKPPRCPKR  480
CSIMPLCRHA TKVKPHKCHY GACPPCRLLC EEEYPCGHMC KLRCHGPKPP PNPEFTLKPR  540
KKKHVHQSEC TPGSSCPPCP ELVWRSCVGQ HIGADRMVGL CMEYMNMSCN IYLVINKATC  600
IILALITTFE ILFLFVVLFS GGMLK*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcriptional regulator. May mediate E2- or E3-dependent ubiquitination. Required to gate light sensitivity during the night. Regulates the speed of the clock by acting in the feedback loop between CCA1, LHY and APRR1/TOC1. Promotes the expression of CCA1 at night but not by days. This activational effect is enhanced by interaction with ADO1/ZTL. Association with ADO1/ZTL is not leading to the degradation of NFXL2. Confers sensitivity to osmotic stress such as high salinity. Prevents H(2)O(2) production and abscisic acid accumulation. Part of a regulatory network that integrates the biosynthesis and action of abscisic acid, reactive oxygen species and cuticle components. {ECO:0000269|PubMed:16905136, ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:21429190, ECO:0000269|PubMed:22073231, ECO:0000269|PubMed:22516817}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation with a peak of expression at or before dawn. Not regulated by biotic and abiotic stresses, by light and nutrient conditions or upon treatment with elicitors, chemicals, abscisic acid or phytohormones. {ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:22073231}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024024682.10.0NF-X1-type zinc finger protein NFXL2
SwissprotQ9FFK80.0NFXL2_ARATH; NF-X1-type zinc finger protein NFXL2
TrEMBLA0A2P5EM310.0A0A2P5EM31_TREOI; Zinc finger, NF-X1-type
STRINGXP_009369168.10.0(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF102253237
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G05660.10.0sequence-specific DNA binding transcription factors;zinc ion binding;sequence-specific DNA binding transcription factors