PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

HL.SW.v1.0.G016927.1

Organism

Humulus lupulus

Taxonomic ID

3486

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

bHLH

Protein Properties

Length: 230aa MW: 25573.1 Da PI: 7.5775

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G016927.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.7	2.7e-10	74	120	5	54
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 + rE+ RRd++N++f eL ++l + + +K++K iL Av+ +++L HL.SW.v1.0.G016927.1 74 KACREKMRRDKLNDRFLELGSILDPG---RPPKMDKGVILGDAVRMVNQL 120 678********************8...89*************9999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.76	69	120	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.95E-8	73	125	No hit	No description
Pfam	PF00010	9.0E-8	73	120	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	2.09E-13	73	140	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.1E-8	75	126	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	9.9E-15	76	142	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd14686	8.65E-5	125	158	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 230 aa Download sequence Send to blast
MSSAGNPNWV FDYSLIEDLP NLEPPGFTWP SHSFTDPTDL SVDFDDSFGN DEGLKETGSR 60 KRVRPGSCST TGSKACREKM RRDKLNDRFL ELGSILDPGR PPKMDKGVIL GDAVRMVNQL 120 RMESQKLKQS NESLQDKINE LKAEKNELRD EKQRLKAEKD ILDKQVKAMT AQPSFMHPPA 180 MPPPFARPGH VVGGKLVPFV GYPGLSMWQF MPPAAVDTSQ DHVLRPPVA*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024018931.1	1e-127	transcription factor bHLH115
Swissprot	Q9FH37	7e-88	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A0A2P5CVA0	1e-144	A0A2P5CVA0_PARAD; Basic helix-loop-helix transcription factor
STRING	XP_008224874.1	1e-119	(Prunus mume)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1602	34	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	2e-83	bHLH family protein

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]