PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G016601.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family E2F/DP
Protein Properties Length: 349aa    MW: 38425.8 Da    PI: 5.6506
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G016601.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP87.31.1e-2791173271
               E2F_TDP   2 keksLrlltqkflklleksee.givtlnevakeLvse................dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                           ++++Lr++++k   ++ek+e+ g++t+neva+eLv+e                d+kn+rRR+YD+lNVL+a+++i+k +k+ei+wkg
  HL.SW.v1.0.G016601.1  91 SGRGLRQFSMK---VCEKVESkGRTTYNEVADELVAEfadpgssvttpdqqqyDEKNIRRRVYDALNVLMAMDIISK-DKKEIQWKG 173
                           689********...*****999*******************************************************.*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0094046.0E-1353348IPR015648Transcription factor DP
Gene3DG3DSA:1.10.10.102.8E-4686179IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.8E-3490173IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.0E-2592173IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.9E-2193174IPR011991Winged helix-turn-helix DNA-binding domain
CDDcd144585.88E-45178281IPR014889Transcription factor DP, C-terminal
SMARTSM011381.3E-70180346IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440743.14E-43180287No hitNo description
PfamPF087813.6E-42181290IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 349 aa     Download sequence    Send to blast
MGNRTQPTTR ADDDDDLPGL ATTVSGQSVS MSGSVGSPSS RSEQTMATPA SDNTFLRLNH  60
LDIHGDDAGS QGAVGSKKKK RGQRAVGGDK SGRGLRQFSM KVCEKVESKG RTTYNEVADE  120
LVAEFADPGS SVTTPDQQQY DEKNIRRRVY DALNVLMAMD IISKDKKEIQ WKGLPRTSVN  180
DIEELKTERL GLRNRIEKKT AYLQELEEQY VGLQNLIQRN EQLYSSGNAP SGGVALPFIL  240
VQTRPHATVE VEISEDMQLV HFDFNSTPFE LHDDNYVLKA MKFCETSSHG DDDEMAHNFT  300
ADGGEGSSRL SMYQTQIPPL PSMSNTPVRN PTSPPLPGIL KARVKHEH*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B2e-3484178193PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015878523.10.0transcription factor-like protein DPB isoform X2
SwissprotQ9FNY21e-169DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A2P5CN000.0A0A2P5CN00_TREOI; DP transcription factor
STRINGXP_004137174.10.0(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33213366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.11e-159Transcription factor DP