PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

HL.SW.v1.0.G012605.1

Organism

Humulus lupulus

Taxonomic ID

3486

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

HSF

Protein Properties

Length: 518aa MW: 56347.8 Da PI: 4.4751

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G012605.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	113.6	1.3e-35	42	133	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgk 90 Fl+k+y++++d++++ ++sws ++nsfvv+++ efa+++LpkyFkhsnf+SFvRQLn+YgF+kv+ ++ weF+++ F +g+ HL.SW.v1.0.G012605.1 42 FLSKTYDMVDDSATDPIVSWSPTNNSFVVWNPPEFARDLLPKYFKHSNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQ 121 9******************999*************************************999.........******** PP XXXXXXXXXXXX CS HSF_DNA-bind 91 kellekikrkks 102 k+ll++i+r+k HL.SW.v1.0.G012605.1 122 KHLLKSINRRKP 133 *******986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	3.0E-39	36	126	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	8.16E-36	37	131	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	2.2E-63	38	131	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	9.8E-20	42	65	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	5.4E-32	42	131	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	9.8E-20	80	92	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	81	105	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	9.8E-20	93	105	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009408	Biological Process	response to heat
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 518 aa Download sequence Send to blast
MDGATGGGEA PSGGGGAQPA VPAPAPAPVP APIPNANAPP PFLSKTYDMV DDSATDPIVS 60 WSPTNNSFVV WNPPEFARDL LPKYFKHSNF SSFVRQLNTY GFRKVDPDRW EFANEGFLRG 120 QKHLLKSINR RKPAHGHSQQ QPQSSHGQST MGACVEVGKF GLEEEVERLK RDKNVLMQEL 180 VRLRQQQQST DNQLQTMVQR LQGMEQRQQQ MMSFLAKAVQ SPGFLAQFVQ QQNESNRRIS 240 EANKKRRLRQ EGIAESNLSA ASDGQIVKYQ PLMNESAKAM LRQMMKVDTP SGMDTFNKSK 300 DGFLIGDGSS SSSTAADSRS SSSRVSGVTL QEVLPTSGQT PSVPLSSGVA APAVSESSPQ 360 LLTSEKVTTA QFPDISVLVG SQEAPSLPIS QGDVVMPELS EIPEMDSEDN FLSNETGGFL 420 DPESLGLIGS MSIDLDDIAP DPDIDALLDN STFWDDLLLQ SPMAEELSPD GTSKDIEVQV 480 QPKENGWNKT QNMDNLTEKM GLLTSDGKGL IYEESYY*

Sequence ? help Back to Top

Protein Sequence Length: 518 aa Download sequence Send to blast

MDGATGGGEA PSGGGGAQPA VPAPAPAPVP APIPNANAPP PFLSKTYDMV DDSATDPIVS  60
WSPTNNSFVV WNPPEFARDL LPKYFKHSNF SSFVRQLNTY GFRKVDPDRW EFANEGFLRG  120
QKHLLKSINR RKPAHGHSQQ QPQSSHGQST MGACVEVGKF GLEEEVERLK RDKNVLMQEL  180
VRLRQQQQST DNQLQTMVQR LQGMEQRQQQ MMSFLAKAVQ SPGFLAQFVQ QQNESNRRIS  240
EANKKRRLRQ EGIAESNLSA ASDGQIVKYQ PLMNESAKAM LRQMMKVDTP SGMDTFNKSK  300
DGFLIGDGSS SSSTAADSRS SSSRVSGVTL QEVLPTSGQT PSVPLSSGVA APAVSESSPQ  360
LLTSEKVTTA QFPDISVLVG SQEAPSLPIS QGDVVMPELS EIPEMDSEDN FLSNETGGFL  420
DPESLGLIGS MSIDLDDIAP DPDIDALLDN STFWDDLLLQ SPMAEELSPD GTSKDIEVQV  480
QPKENGWNKT QNMDNLTEKM GLLTSDGKGL IYEESYY*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	4e-26	34	131	18	129	Heat shock factor protein 1
5d5v_B	4e-26	34	131	18	129	Heat shock factor protein 1
5d5v_D	4e-26	34	131	18	129	Heat shock factor protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010096952.1	0.0	heat shock factor protein HSF8
Swissprot	Q40152	1e-177	HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBL	A0A2P5ASY7	0.0	A0A2P5ASY7_TREOI; Heat shock transcription factor
STRING	XP_010096952.1	0.0	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1843	31	69

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G32330.1	1e-122	heat shock transcription factor A1D

Publications ? help Back to Top
Zhu B, et al. Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max). J. Plant Res., 2006. 119(3): p. 247-56 [PMID:16570125] Cai SY, et al. HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants. J. Pineal Res., 2017. [PMID:28095626] Zhou J, et al. Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1. Plant Physiol., 2018. 176(3): p. 2456-2471 [PMID:29339397]