PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G010109.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family TALE
Protein Properties Length: 340aa    MW: 38810.1 Da    PI: 5.5742
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G010109.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox28.72.3e-092823162155
                           HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
              Homeobox  21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                           k +yp+++++  LA+ +gL+++q+ +WF N+R ++
  HL.SW.v1.0.G010109.1 282 KWPYPTEADKNALAETTGLDQKQINNWFINQRKRH 316
                           669*****************************885 PP
2ELK292.5e-10236257122
                   ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                           +LK+ Llr Y++++g+Lk EFs
  HL.SW.v1.0.G010109.1 236 DLKDKLLRRYGSHIGTLKLEFS 257
                           69*******************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012558.5E-2293137IPR005540KNOX1
PfamPF037901.0E-2095136IPR005540KNOX1
SMARTSM012562.8E-26144195IPR005541KNOX2
PfamPF037911.8E-24148194IPR005541KNOX2
PROSITE profilePS512139.812236256IPR005539ELK domain
SMARTSM011882.6E-5236257IPR005539ELK domain
PfamPF037893.4E-8236257IPR005539ELK domain
PROSITE profilePS5007112.762256319IPR001356Homeobox domain
SuperFamilySSF466894.71E-19257330IPR009057Homeodomain-like
SMARTSM003891.6E-12258323IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.603.3E-27261320IPR009057Homeodomain-like
CDDcd000867.39E-12265320No hitNo description
PfamPF059203.9E-17276315IPR008422Homeobox KN domain
PROSITE patternPS000270294317IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010073Biological Processmeristem maintenance
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 340 aa     Download sequence    Send to blast
MDEMYGLEAT TSVEYSDKGL MSPENDDLLL PSDYPTFSFR DHRVLPSFFG SDDNHHHHHS  60
NSSHNHHHQQ LLSAASAAIS EAVSFQREED VSNLIKTKIA SHPTYPRLLQ AYIDCQKVGA  120
PPEIASFLEE IRRKNEPYKR DSIISTCLGA DPELDEFMET YCDMLVKYKS DLARPFDEAT  180
TFLSKIEIQL SNLCSSTGAT NTRGLSDEGG ASSEEELSGG EVEGQQESQL RGEDRDLKDK  240
LLRRYGSHIG TLKLEFSKKK KKGKLPREAR QTLLDWWNLH YKWPYPTEAD KNALAETTGL  300
DQKQINNWFI NQRKRHWKPS ENMQFAVMDN LSGQFYRDD*
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024023903.11e-174homeobox protein knotted-1-like 6
SwissprotQ84JS61e-138KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A2P5FMJ60.0A0A2P5FMJ6_TREOI; Knotted-like homeobox transcription factor
STRINGXP_010100424.11e-169(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF62034125
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.11e-117KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]