PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

HL.SW.v1.0.G010018.1

Organism

Humulus lupulus

Taxonomic ID

3486

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

G2-like

Protein Properties

Length: 356aa MW: 38864.2 Da PI: 5.0989

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G010018.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	95	5.8e-30	156	209	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 +prl+Wtp+LH+rFv++v++L G+++A+Pkti++lm+v+gLt+e+v+SHLQkYRl HL.SW.v1.0.G010018.1 156 RPRLVWTPQLHKRFVDVVAHL-GIKNAVPKTIMQLMNVEGLTRENVASHLQKYRL 209 59*****************.******************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	10.061	153	212	IPR017930	Myb domain
SuperFamily	SSF46689	1.79E-19	153	213	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	4.0E-30	155	214	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	1.8E-23	157	209	IPR006447	Myb domain, plants
Pfam	PF00249	6.5E-8	159	208	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0042753	Biological Process	positive regulation of circadian rhythm
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 356 aa Download sequence Send to blast
MGEEVRMGDY EGGTDDGGAD EERVLEWETG LPSVDDLTPL SQPLIPPELA SAFSISPVQY 60 RSLVDVNRAS RDTLSSLRGM QSQAFSSNNF KSFGDSPDSM VVENDENENE NDDDDNRDGS 120 GSDSRKSRKI DCVEEADFAL PTDNPTDDPS ARTLKRPRLV WTPQLHKRFV DVVAHLGIKN 180 AVPKTIMQLM NVEGLTRENV ASHLQKYRLY LKRMQGLSND DPSSSDQLFS STPVPQSFNE 240 SGGSGHSHGN GHLPVPMPIP YQSMMSMPVL GMAHGGHGHM GIPVGAPNGA VGYHGFESHH 300 PYSMMQQRDW SGNKYGSVKL SKLVEVNSWS STSKVARLLI LNLTSMGREG FLGTT*

Sequence ? help Back to Top

Protein Sequence Length: 356 aa Download sequence Send to blast

MGEEVRMGDY EGGTDDGGAD EERVLEWETG LPSVDDLTPL SQPLIPPELA SAFSISPVQY  60
RSLVDVNRAS RDTLSSLRGM QSQAFSSNNF KSFGDSPDSM VVENDENENE NDDDDNRDGS  120
GSDSRKSRKI DCVEEADFAL PTDNPTDDPS ARTLKRPRLV WTPQLHKRFV DVVAHLGIKN  180
AVPKTIMQLM NVEGLTRENV ASHLQKYRLY LKRMQGLSND DPSSSDQLFS STPVPQSFNE  240
SGGSGHSHGN GHLPVPMPIP YQSMMSMPVL GMAHGGHGHM GIPVGAPNGA VGYHGFESHH  300
PYSMMQQRDW SGNKYGSVKL SKLVEVNSWS STSKVARLLI LNLTSMGREG FLGTT*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5lxu_A	2e-35	156	212	1	57	Transcription factor LUX
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:21236673, ECO:0000269\|PubMed:21753751, ECO:0000269\|PubMed:22311777}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00014	PBM	Transfer from AT3G46640	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian oscillation with peaks at subjective dusk. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:17132630, ECO:0000269\|PubMed:21753751}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010106529.1	1e-149	transcription factor BOA
Refseq	XP_024028072.1	1e-149	transcription factor BOA
Swissprot	Q9SNB4	4e-87	PCL1_ARATH; Transcription factor LUX
TrEMBL	A0A2P5DQN6	1e-180	A0A2P5DQN6_PARAD; Octamer-binding transcription factor
STRING	XP_010106529.1	1e-148	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF6957	33	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G46640.2	2e-80	G2-like family protein

Publications ? help Back to Top
Higham CF,Husmeier D A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics, 2013. 14 Suppl 10: p. S3 [PMID:24267177]