PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G007058.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family G2-like
Protein Properties Length: 763aa    MW: 82622.5 Da    PI: 7.1901
Description G2-like family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G007058.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like86.92e-27193247156
               G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRla 56 
                           k +++WtpeLH+rFv+aveqL G +kA+P++ilelm++++Lt+++++SHLQkYR++
  HL.SW.v1.0.G007058.1 193 KVKVDWTPELHRRFVQAVEQL-GVDKAVPSRILELMGIDCLTRHNIASHLQKYRSH 247
                           5689*****************.********************************86 PP
2G2-like85.26.6e-27475526456
               G2-like   4 lrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRla 56 
                           ++WtpeLH+rFv+aveqL G +kA+P++ilelm++++Lt+++++SHLQkYR++
  HL.SW.v1.0.G007058.1 475 VDWTPELHRRFVQAVEQL-GVDKAVPSRILELMGIDCLTRHNIASHLQKYRSH 526
                           79****************.********************************86 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129418.152190249IPR017930Myb domain
Gene3DG3DSA:1.10.10.602.6E-26191250IPR009057Homeodomain-like
SuperFamilySSF466898.17E-19191250IPR009057Homeodomain-like
TIGRFAMsTIGR015574.0E-26193247IPR006447Myb domain, plants
PfamPF002499.7E-8196245IPR001005SANT/Myb domain
PROSITE profilePS5129414.687469528IPR017930Myb domain
SuperFamilySSF466891.52E-18471529IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.7E-25472529IPR009057Homeodomain-like
TIGRFAMsTIGR015571.0E-25473526IPR006447Myb domain, plants
PfamPF002491.7E-7476524IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0007165Biological Processsignal transduction
GO:0009658Biological Processchloroplast organization
GO:0009910Biological Processnegative regulation of flower development
GO:0010380Biological Processregulation of chlorophyll biosynthetic process
GO:0010638Biological Processpositive regulation of organelle organization
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:1900056Biological Processnegative regulation of leaf senescence
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 763 aa     Download sequence    Send to blast
MVIGMLAVSS LRDTYRDEKQ GGETVETSNI NFSINAGDGF PDFADCIDFD DLFIGINVDG  60
DVLPDLEMDS EILADFSAED YNSDVNASPS SAEKSADIDD NSVSINSTIT SSTTTHRAEE  120
EDDKKIKFTT TENEDDKVSG SGSGLDSSLS GSVTGRNVAS TNTNKEAADK GGGKKSSSST  180
AQSKNNNSQG KRKVKVDWTP ELHRRFVQAV EQLGVDKAVP SRILELMGID CLTRHNIASH  240
LQKYRSHRKH LLAREAEAAS WSQRRQMFGP AGGGGGGAVS GKRDVGPWPV LPTMGFPPMT  300
PPPVPALVPP PMHHHFRPLH VWGHPTVDQS LMHVWPPKHL PHSPSHHPPP QAWPPVPPPP  360
PPQDPSYWHS HHQRVPSTLT PGTPCFPPPM ATPRFGTPTV PGIPPPHAMY KVEPGIGNLN  420
PGQSGPHPLF DFHPSKESVD AAIGDVLAKP WLPLPLGLKP PSTDSVMGEL QRQGVDWTPE  480
LHRRFVQAVE QLGVDKAVPS RILELMGIDC LTRHNIASHL QKYRSHRKHL LAREAEAASW  540
SQRRQMFGPA GGGGGGAVSG KRDVGPWPVL PTMGFPPMTP PPVPPLVPPP MHHHFRPLHV  600
WGHPTVDQSL MHVWPPKHLP HSPSHHPPPQ AWPPVPPPPP PQDPSYWHSH HQRVPSTLTP  660
GTPCFPQPMA TPRFATPTVP GIPPPHAMYK VEPGIGNLNP GQSGPHPLFD FHPSKESVDA  720
AIGDVLAKPW LPLPLGLKPP STDSVMGELQ RQGVPKIPPS CA*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A6e-16190524257ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that functions with GLK2 to promote chloroplast development. Acts as an activator of nuclear photosynthetic genes involved in chlorophyll biosynthesis, light harvesting, and electron transport. Acts in a cell-autonomous manner to coordinate and maintain the photosynthetic apparatus within individual cells. May function in photosynthetic capacity optimization by integrating responses to variable environmental and endogenous cues (PubMed:11828027, PubMed:12220263, PubMed:17533111, PubMed:18643989, PubMed:19376934, PubMed:19383092, PubMed:19726569). Prevents premature senescence (PubMed:23459204). {ECO:0000269|PubMed:11828027, ECO:0000269|PubMed:12220263, ECO:0000269|PubMed:17533111, ECO:0000269|PubMed:18643989, ECO:0000269|PubMed:19376934, ECO:0000269|PubMed:19383092, ECO:0000269|PubMed:19726569, ECO:0000269|PubMed:23459204}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00022PBMTransfer from AT2G20570Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By light. Repressed by BZR2. {ECO:0000269|PubMed:12220263, ECO:0000269|PubMed:21214652}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010093955.11e-155transcription activator GLK1 isoform X2
SwissprotQ9SIV31e-86GLK1_ARATH; Transcription activator GLK1
TrEMBLA0A2P5B6N00.0A0A2P5B6N0_PARAD; Octamer-binding transcription factor
STRINGXP_010093955.11e-154(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF42423461
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G20570.13e-69GBF's pro-rich region-interacting factor 1
Publications ? help Back to Top
  1. Leister D,Kleine T
    Definition of a core module for the nuclear retrograde response to altered organellar gene expression identifies GLK overexpressors as gun mutants.
    Physiol Plant, 2016. 157(3): p. 297-309
    [PMID:26876646]
  2. Nagatoshi Y, et al.
    GOLDEN 2-LIKE transcription factors for chloroplast development affect ozone tolerance through the regulation of stomatal movement.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(15): p. 4218-23
    [PMID:27035938]
  3. Tokumaru M, et al.
    Ubiquitin-Proteasome Dependent Regulation of the GOLDEN2-LIKE 1 Transcription Factor in Response to Plastid Signals.
    Plant Physiol., 2017. 173(1): p. 524-535
    [PMID:27821720]
  4. Ni F, et al.
    Turnip Yellow Mosaic Virus P69 Interacts with and Suppresses GLK Transcription Factors to Cause Pale-Green Symptoms in Arabidopsis.
    Mol Plant, 2017. 10(5): p. 764-766
    [PMID:27964999]
  5. Wang H,Seo JK,Gao S,Cui X,Jin H
    Silencing of AtRAP, a target gene of a bacteria-induced small RNA, triggers antibacterial defense responses through activation of LSU2 and down-regulation of GLK1.
    New Phytol., 2017. 215(3): p. 1144-1155
    [PMID:28656601]