PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

HL.SW.v1.0.G005448.1

Organism

Humulus lupulus

Taxonomic ID

3486

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

C2H2

Protein Properties

Length: 484aa MW: 53544.5 Da PI: 8.9375

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G005448.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.8	0.00036	81	103	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k + +s+ k H +t+ HL.SW.v1.0.G005448.1 81 WKCEKCSKKYAVQSDWKAHSKTC 103 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	3.4E-4	69	102	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding

Sequence ? help Back to Top
Protein Sequence Length: 484 aa Download sequence Send to blast
MINIKIQVRS KGFQRDQNLQ LHRRGHNLPW KLRQRSPNEV VRKRVYICPE TSCVHHNPTR 60 ALGDLTGIKK HFCRKHGEKK WKCEKCSKKY AVQSDWKAHS KTCGTREYKC ECGTIFSRRD 120 SFITHRAFCD AIAEENNKTT TLQRQNISSS TQPELVSSII STINDENDNK YANLQAETTS 180 SDQFKHMMMN MKNPLILDHH HHQSLNNSAM APGGSFFSRS SLNNMIINNG STTTTNISSS 240 APLSFDHHHS QNNDHHFGGG GEFYLSATAL LQKAAQMGAT TVSSASSAMA PSTYASLDHQ 300 LFAKKDHPLL QEYQMNSTST TATTTTATPP PQFFNVNGNH HNNDIDNNNN NKNVGLFSGL 360 LFDHQNHAAG GGGGDSTFMK EMELSMNNDN ASNVVLHGGN SSSSLTTTGG GDVMTVDFLG 420 IGSRPVSRQG NFHHDQQKKQ VVDVVNNLRF GGGINGSHHP SMQTTLTQFQ QHAALMEKHA 480 WEV*

Sequence ? help Back to Top

Protein Sequence Length: 484 aa Download sequence Send to blast

MINIKIQVRS KGFQRDQNLQ LHRRGHNLPW KLRQRSPNEV VRKRVYICPE TSCVHHNPTR  60
ALGDLTGIKK HFCRKHGEKK WKCEKCSKKY AVQSDWKAHS KTCGTREYKC ECGTIFSRRD  120
SFITHRAFCD AIAEENNKTT TLQRQNISSS TQPELVSSII STINDENDNK YANLQAETTS  180
SDQFKHMMMN MKNPLILDHH HHQSLNNSAM APGGSFFSRS SLNNMIINNG STTTTNISSS  240
APLSFDHHHS QNNDHHFGGG GEFYLSATAL LQKAAQMGAT TVSSASSAMA PSTYASLDHQ  300
LFAKKDHPLL QEYQMNSTST TATTTTATPP PQFFNVNGNH HNNDIDNNNN NKNVGLFSGL  360
LFDHQNHAAG GGGGDSTFMK EMELSMNNDN ASNVVLHGGN SSSSLTTTGG GDVMTVDFLG  420
IGSRPVSRQG NFHHDQQKKQ VVDVVNNLRF GGGINGSHHP SMQTTLTQFQ QHAALMEKHA  480
WEV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	8e-35	77	146	3	72	Zinc finger protein JACKDAW
5b3h_F	8e-35	77	146	3	72	Zinc finger protein JACKDAW
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015875094.1	1e-122	protein indeterminate-domain 7
Swissprot	Q9SCQ6	1e-85	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A2P5CFT0	0.0	A0A2P5CFT0_PARAD; TFIIH C1-like domain containing protein
STRING	XP_010088951.1	1e-120	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF181	34	275

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	3e-73	indeterminate(ID)-domain 2

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]